Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Sha-Sha Yuan"'
Autor:
Miao-Zhen Qiu, Qingjian Chen, Dan-Yang Zheng, Qi Zhao, Qi-Nian Wu, Zhi-Wei Zhou, Li-Qiong Yang, Qiu-Yun Luo, Yu-Ting Sun, Ming-Yu Lai, Sha-Sha Yuan, Feng-Hua Wang, Hui-Yan Luo, Feng Wang, Yu-Hong Li, Hui-Zhong Zhang, Rui-Hua Xu
Publikováno v:
Cell Reports, Vol 42, Iss 6, Pp 112576- (2023)
Summary: Gastric mixed adenoneuroendocrine carcinoma (MANEC) is a clinically aggressive and heterogeneous tumor composed of adenocarcinoma (ACA) and neuroendocrine carcinoma (NEC). The genomic properties and evolutionary clonal origins of MANEC remai
Externí odkaz:
https://doaj.org/article/bf5aeca0e50d4f5bb3972a430c761164
Autor:
Jing Lu, Ting-Ting Shi, Sha-Sha Yuan, Rong-Rong Xie, Ru-Xuan Zhao, Juan-Juan Zhu, Jin-Kui Yang
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Mutations in KCNH6 has been proved to cause hypoinsulinemia and diabetes in human and mice. Cisapride is a stomach–intestinal motility drug used to treat gastrointestinal dysfunction. Cisapride has been reported to be a potential inhibitor of the K
Externí odkaz:
https://doaj.org/article/300f94c389f24b9d932ea44c1bb03a06
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S7, Pp 1-8 (2019)
Abstract Background Gene co-expression network is a favorable method to reveal the nature of disease. With the development of cancer, the way to build gene co-expression networks based on cancer data has been become a hot spot. However, there are sti
Externí odkaz:
https://doaj.org/article/22d1850f51b045efad4adb2c184da42b
Publikováno v:
Endocrine and Metabolic Science, Vol 5, Iss , Pp 100106- (2021)
A stable narrow range of extracellular calcium concentration in the blood is essential for life. The calcium-sensing receptor (CaSR), a member of the G protein-coupled receptors family, is required to adjust the set point of blood extracellular calci
Externí odkaz:
https://doaj.org/article/2a8c6c43a3e04a188ff7b5eaa76f2dcc
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S8, Pp 1-13 (2019)
Abstract Background Predicting drug-target interactions is time-consuming and expensive. It is important to present the accuracy of the calculation method. There are many algorithms to predict global interactions, some of which use drug-target networ
Externí odkaz:
https://doaj.org/article/1f4c3c4fb72c48639e9357be2240aaf0
Autor:
Xiang-Zhen Kong, Yu Song, Jin-Xing Liu, Chun-Hou Zheng, Sha-Sha Yuan, Juan Wang, Ling-Yun Dai
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The dimensionality reduction method accompanied by different norm constraints plays an important role in mining useful information from large-scale gene expression data. In this article, a novel method named Lp-norm and L2,1-norm constrained graph La
Externí odkaz:
https://doaj.org/article/6f852855d6d44c64999db785db217b35
Autor:
Xiao-Li Wei, Qian-Wen Liu, Fu-Rong Liu, Sha-Sha Yuan, Xiao-Fen Li, Jia-Ning Li, An-Li Yang, Yi-Hong Ling
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
The effect of anti-programmed cell death 1 (PD-1) antibody in Epstein-Barr virus-associated gastric cancer (EBVaGC) was debatable, and no predictive biomarkers for efficacy have been reported. Public reports on anti-PD-1 antibody monotherapy-treated
Externí odkaz:
https://doaj.org/article/639481e994cd44d69c414eb655fac879
Autor:
Jin-Kui Yang, Jing Lu, Sha-Sha Yuan, Asan, Xi Cao, Hai-Yan Qiu, Ting-Ting Shi, Fang-Yuan Yang, Qian Li, Cui-Ping Liu, Qian Wu, Yu-Hui Wang, Hai-Xia Huang, Abudurexiti Kayoumu, Jian-Ping Feng, Rong-Rong Xie, Xiao-Rong Zhu, Chang Liu, Guang-Ran Yang, Ming-Rong Zhang, Chun-Lan Xie, Chen Chen, Bo Zhang, George Liu, Xiu-Qing Zhang, Aimin Xu
Publikováno v:
Cell Reports, Vol 25, Iss 13, Pp 3800-3810.e6 (2018)
Summary: Glucose-stimulated insulin secretion from islet β cells is mediated by KATP channels. However, the role of non-KATP K+ channels in insulin secretion is largely unknown. Here, we show that a non-KATP K+ channel, KCNH6, plays a key role in in
Externí odkaz:
https://doaj.org/article/12fc42142b4642a4b553cc0f1eb5e395
Autor:
Long‐Yan Yang, Cai‐Guo Yu, Xu‐Hong Wang, Sha‐Sha Yuan, Li‐Jie Zhang, Jia‐Nan Lang, Dong Zhao, Ying‐Mei Feng
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 6 (2017)
BackgroundANGPTL4 (angiopoietin‐like protein 4) is a LPL (lipoprotein lipase) inhibitor and is present in high‐density lipoprotein (HDL). However, it is not defined whether ANGPTL4 in HDLs could affect HDL metabolism and function in type 2 diabet
Externí odkaz:
https://doaj.org/article/2a6e99c4b65442f2a4210da18f9916d5
Publikováno v:
Stem Cells International, Vol 2016 (2016)
Despite being featured as metabolic disorder, diabetic patients are largely affected by hyperglycemia-induced vascular abnormality. Accumulated evidence has confirmed the beneficial effect of endothelial progenitor cells (EPCs) in coronary heart dise
Externí odkaz:
https://doaj.org/article/437d64960c1445dba6c336ac68084521