Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells

Autor: Sf, Schmidt, Jg, Madsen, Kø, Frafjord, Lc, Poulsen, Salö S, Boergesen M, Loft A, Bd, Larsen, Ms, Madsen, Jj, Holst, Maechler P, Lt, Dalgaard, Susanne Mandrup

Publikováno v: Europe PubMed Central

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::04d98566fed05d8b04b3df3d1de661a0
http://europepmc.org/abstract/med/27545881

Adipose Kiss1 controls aerobic exercise-related adaptive responses in adipose tissue energy homeostasis.

Autor: Liang C; Department of Sport Biochemistry, School of Sport Science, Beijing Sport University (BSU), Beijing, China.; Laboratory of Sports Stress and Adaptation, General Administration of Sport of China, Beijing, China.; Department of Biochemistry and Molecular Biology, Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark (SDU), Odense, Denmark.; School of Physical Education, Guangxi University (GXU), Nanning, China., Li X; Department of Sport Biochemistry, School of Sport Science, Beijing Sport University (BSU), Beijing, China.; Laboratory of Sports Stress and Adaptation, General Administration of Sport of China, Beijing, China., Song G; Department of Sport Biochemistry, School of Sport Science, Beijing Sport University (BSU), Beijing, China.; Laboratory of Sports Stress and Adaptation, General Administration of Sport of China, Beijing, China., Schmidt SF; Department of Biochemistry and Molecular Biology, Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark (SDU), Odense, Denmark., Sun L; Department of Sport Biochemistry, School of Sport Science, Beijing Sport University (BSU), Beijing, China.; Laboratory of Sports Stress and Adaptation, General Administration of Sport of China, Beijing, China., Chen J; Department of Sport Biochemistry, School of Sport Science, Beijing Sport University (BSU), Beijing, China.; Laboratory of Sports Stress and Adaptation, General Administration of Sport of China, Beijing, China., Pan X; Department of Sport Biochemistry, School of Sport Science, Beijing Sport University (BSU), Beijing, China.; Laboratory of Sports Stress and Adaptation, General Administration of Sport of China, Beijing, China., Zhao H; Department of Sport Biochemistry, School of Sport Science, Beijing Sport University (BSU), Beijing, China.; Laboratory of Sports Stress and Adaptation, General Administration of Sport of China, Beijing, China., Yan Y; Department of Sport Biochemistry, School of Sport Science, Beijing Sport University (BSU), Beijing, China.; Laboratory of Sports Stress and Adaptation, General Administration of Sport of China, Beijing, China.

Publikováno v: FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2024 Jul 15; Vol. 38 (13), pp. e23743.

A macrophage-hepatocyte glucocorticoid receptor axis coordinates fasting ketogenesis.

Autor: Loft A; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany; Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU), Odense 5230, Denmark; Center for Functional Genomics and Tissue Plasticity (ATLAS), SDU, Odense 5230, Denmark., Schmidt SF; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany; Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU), Odense 5230, Denmark; Center for Functional Genomics and Tissue Plasticity (ATLAS), SDU, Odense 5230, Denmark. Electronic address: sfs@bmb.sdu.dk., Caratti G; Institute for Comparative Molecular Endocrinology, Universität Ulm, Ulm 89081, Germany., Stifel U; Institute for Comparative Molecular Endocrinology, Universität Ulm, Ulm 89081, Germany., Havelund J; Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU), Odense 5230, Denmark., Sekar R; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany., Kwon Y; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany., Sulaj A; German Center for Diabetes Research, Neuherberg 85764, Germany; Department of Endocrinology and Clinical Chemistry, Heidelberg University Hospital, Heidelberg 69120, Germany., Chow KK; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany., Alfaro AJ; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany., Schwarzmayr T; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg 85764, Germany., Rittig N; Department of Internal Medicine and Endocrinology (Multilateral Environmental Agreement) and Medical Research Laboratory, Aarhus University Hospital, Aarhus C 8000, Denmark; Steno Diabetes Center Aarhus, Aarhus University, Hedeager 3, 2nd Floor, 8200 Aarhus N, Denmark., Svart M; Department of Internal Medicine and Endocrinology (Multilateral Environmental Agreement) and Medical Research Laboratory, Aarhus University Hospital, Aarhus C 8000, Denmark; Steno Diabetes Center Aarhus, Aarhus University, Hedeager 3, 2nd Floor, 8200 Aarhus N, Denmark., Tsokanos FF; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany., Maida A; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany., Blutke A; Research Unit Analytical Pathology, Helmholtz Center Munich, Neuherberg 85764, Germany., Feuchtinger A; Research Unit Analytical Pathology, Helmholtz Center Munich, Neuherberg 85764, Germany., Møller N; Department of Internal Medicine and Endocrinology (Multilateral Environmental Agreement) and Medical Research Laboratory, Aarhus University Hospital, Aarhus C 8000, Denmark., Blüher M; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG), Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig 04103, Germany., Nawroth P; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Department of Endocrinology and Clinical Chemistry, Heidelberg University Hospital, Heidelberg 69120, Germany., Szendrödi J; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Department of Endocrinology and Clinical Chemistry, Heidelberg University Hospital, Heidelberg 69120, Germany., Færgeman NJ; Department of Biochemistry and Molecular Biology, University of Southern Denmark (SDU), Odense 5230, Denmark., Zeigerer A; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany., Tuckermann J; Institute for Comparative Molecular Endocrinology, Universität Ulm, Ulm 89081, Germany. Electronic address: jan.tuckermann@uni-ulm.de., Herzig S; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Internal Medicine, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Technical University Munich, Munich 80333, Germany; German Center for Diabetes Research, Neuherberg 85764, Germany. Electronic address: stephan.herzig@helmholtz-muenchen.de.

Publikováno v: Cell metabolism [Cell Metab] 2022 Mar 01; Vol. 34 (3), pp. 473-486.e9. Date of Electronic Publication: 2022 Feb 03.

Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication.

Autor: Loft A; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark. Electronic address: anne.loft@helmholtz-muenchen.de., Alfaro AJ; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Schmidt SF; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark., Pedersen FB; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense 5230, Denmark., Terkelsen MK; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense 5230, Denmark., Puglia M; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark., Chow KK; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Feuchtinger A; Research Unit Analytical Pathology, Helmholtz Zentrum München, Neuherberg 85764, Germany., Troullinaki M; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Maida A; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Wolff G; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Sakurai M; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Berutti R; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg 85764, Germany., Ekim Üstünel B; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Nawroth P; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany; Department of Medicine I and Clinical Chemistry, Heidelberg University Hospital, Heidelberg 69120, Germany., Ravnskjaer K; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense 5230, Denmark., Diaz MB; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany., Blagoev B; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense 5230, Denmark; Center for Functional Genomics and Tissue Plasticity (ATLAS), University of Southern Denmark, Odense 5230, Denmark., Herzig S; Institute for Diabetes and Cancer (IDC), Helmholtz Diabetes Center, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Joint Heidelberg-IDC Translational Diabetes Program, Heidelberg University Hospital, Heidelberg 69120, Germany; Molecular Metabolic Control, Medical Faculty, Technical University Munich, München 80333, Germany; German Center for Diabetes Research (DZD), Neuherberg 85764, Germany. Electronic address: stephan.herzig@helmholtz-muenchen.de.

Publikováno v: Cell metabolism [Cell Metab] 2021 Aug 03; Vol. 33 (8), pp. 1685-1700.e9. Date of Electronic Publication: 2021 Jul 07.

Psychometric evaluation of the Danish version of a modified Revised American Pain Society Patient Outcome Questionnaire (APS-POQ-R-D) for patients hospitalized with acute abdominal pain.

Autor: Schultz H; Surgical Department, Odense University Hospital, J.B. Winsløws Vej 4, 5000 Odense C, Denmark.; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.; OPEN - Odense Patient Data Explorative Network, Odense University Hospital, Odense, Denmark, Phone: (+45) 2240 1513., Skræp U; Surgical Department, Odense University Hospital, Svendborg, Denmark., Schultz Larsen T; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark., Rekvad LE; Emergency Department, Odense University Hospital, Odense, Denmark., Littau-Larsen J; Emergency Department, Odense University Hospital, Svendborg, Denmark., Schmidt SF; Emergency Department, Odense University, Svendborg, Denmark., Möller S; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.; OPEN - Odense Patient Data Explorative Network, Odense University Hospital, Odense, Denmark., Qvist N; Institute of Clinical Research, University of Southern Denmark, Odense, Denmark.; Surgical Department, Odense University Hospital, Odense, Denmark.

Publikováno v: Scandinavian journal of pain [Scand J Pain] 2019 Jan 28; Vol. 19 (1), pp. 117-130.