Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Seyyedmohsen Hosseinibarkooie"'
Autor:
Biljana Ermanoska, Bob Asselbergh, Laura Morant, Maria-Luise Petrovic-Erfurth, Seyyedmohsen Hosseinibarkooie, Ricardo Leitão-Gonçalves, Leonardo Almeida-Souza, Sven Bervoets, Litao Sun, LaTasha Lee, Derek Atkinson, Akram Khanghahi, Ivaylo Tournev, Patrick Callaerts, Patrik Verstreken, Xiang-Lei Yang, Brunhilde Wirth, Avital A. Rodal, Vincent Timmerman, Bruce L. Goode, Tanja A. Godenschwege, Albena Jordanova
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Mutations in tRNA ligases, essential components of the translational machinery, are associated with Charcot-Marie-Tooth peripheral neuropathy, but the mechanistic details are not known. The authors report that the tyrosyl-tRNA synthetase is an evolut
Externí odkaz:
https://doaj.org/article/10366423a6464375b1b796d7bfb9bd6f
Autor:
Melissa B. Walsh, Eva Janzen, Emily Wingrove, Seyyedmohsen Hosseinibarkooie, Natalia Rodriguez Muela, Lance Davidow, Maria Dimitriadi, Erika M. Norabuena, Lee L. Rubin, Brunhilde Wirth, Anne C. Hart
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-19 (2020)
Abstract Background Understanding the genetic modifiers of neurodegenerative diseases can provide insight into the mechanisms underlying these disorders. Here, we examine the relationship between the motor neuron disease spinal muscular atrophy (SMA)
Externí odkaz:
https://doaj.org/article/d6f829f77b844f8aab92f9979c421e69
Autor:
Eva Janzen, Lisa Wolff, Natalia Mendoza-Ferreira, Kristina Hupperich, Andrea Delle Vedove, Seyyedmohsen Hosseinibarkooie, Min Jeong Kye, Brunhilde Wirth
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Many neurodegenerative disorders share common pathogenic pathways such as endocytic defects, Ca2+ misregulation and defects in actin dynamics. Factors acting on these shared pathways are highly interesting as a therapeutic target. Plastin 3 (PLS3), a
Externí odkaz:
https://doaj.org/article/65c3660dc28c4f03babf89ef4c4949db
Autor:
Aaradhita Upadhyay, Seyyedmohsen Hosseinibarkooie, Svenja Schneider, Anna Kaczmarek, Laura Torres-Benito, Natalia Mendoza-Ferreira, Melina Overhoff, Roman Rombo, Vanessa Grysko, Min Jeong Kye, Natalia L. Kononenko, Brunhilde Wirth
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Neurocalcin delta (NCALD) is a brain-enriched neuronal calcium sensor and its reduction acts protective against spinal muscular atrophy (SMA). However, the physiological function of NCALD and implications of NCALD reduction are still elusive. Here, w
Externí odkaz:
https://doaj.org/article/35272ecbff7c41e6b8cfd4fe658f58e1
Autor:
Eike A Strathmann, Miriam Peters, Seyyedmohsen Hosseinibarkooie, Frank W Rigo, C Frank Bennett, Phillip G Zaworski, Karen S Chen, Michael Nothnagel, Brunhilde Wirth
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203398 (2018)
OBJECTIVES:Spinal muscular atrophy (SMA) is a devastating motor neuron disorder caused by homozygous loss of the survival motor neuron 1 (SMN1) gene and insufficient functional SMN protein produced by the SMN2 copy gene. Additional genetic protective
Externí odkaz:
https://doaj.org/article/371689b6394549edac70c92ed9384ded
Autor:
Eike A. Strathmann, Irmgard Hölker, Nikolai Tschernoster, Seyyedmohsen Hosseinibarkooie, Julien Come, Cecile Martinat, Janine Altmüller, Brunhilde Wirth
Publikováno v:
The American Journal of Human Genetics. 110:442-459
Autor:
Ku-Lung Hsu, Heather A. Ferris, Jeffrey W. Brulet, Mitchell E. Granade, Thurl E. Harris, Tao Huang, Seyyedmohsen Hosseinibarkooie, Adam L. Borne
Publikováno v:
Chemical Science
Sulfonyl-triazoles are a new class of electrophiles that mediate covalent reaction with tyrosine residues on proteins through sulfur-triazole exchange (SuTEx) chemistry. Recent studies demonstrate the broad utility and tunability of SuTEx chemistry f
Autor:
Anthony M. Ciancone, Seyyedmohsen Hosseinibarkooie, Dina L. Bai, Adam L. Borne, Heather A. Ferris, Ku-Lung Hsu
Publikováno v:
Cell Chemical Biology. 29:1709-1720.e7
RNA granules are cytoplasmic condensates that organize biochemical and signaling complexes in response to cellular stress. Functional proteomic investigations under RNA-granule-inducing conditions are needed to identify protein sites involved in coup
Autor:
Maria Dimitriadi, Anne C. Hart, Melissa B. Walsh, Natalia Rodriguez Muela, Erika M. Norabuena, Seyyedmohsen Hosseinibarkooie, Eva Janzen, Brunhilde Wirth, Emily Wingrove, Lee L. Rubin, Lance S. Davidow
Publikováno v:
BMC Biology
BMC Biology, Vol 18, Iss 1, Pp 1-19 (2020)
BMC Biology, Vol 18, Iss 1, Pp 1-19 (2020)
Background Understanding the genetic modifiers of neurodegenerative diseases can provide insight into the mechanisms underlying these disorders. Here, we examine the relationship between the motor neuron disease spinal muscular atrophy (SMA), which i
Autor:
Michael Nothnagel, Frank Rigo, Brunhilde Wirth, Miriam Peters, C. Frank Bennett, Seyyedmohsen Hosseinibarkooie, Karen S. Chen, Eike A. Strathmann, Phillip G. Zaworski
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0203398 (2018)
PLoS ONE, Vol 13, Iss 9, p e0203398 (2018)
Objectives: Spinal muscular atrophy (SMA) is a devastating motor neuron disorder caused by homozygous loss of the survival motor neuron 1 (SMN1) gene and insufficient functional SMN protein produced by the SMN2 copy gene. Additional genetic protectiv