Zobrazeno 1 - 10
of 267
pro vyhledávání: '"Seyun Kim"'
Autor:
Sehoon Hong, Kyurae Kim, Young-Ri Shim, Jiyeon Park, Sung Eun Choi, Hyungyu Min, Seulgi Lee, Ji-Joon Song, Suk-Jo Kang, Won-Il Jeong, Rho Hyun Seong, Seyun Kim
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Background Phospholipase C gamma 1 (PLCγ1) is an important mediator of the T cell receptor (TCR) and growth factor signaling. PLCγ1 is activated by Src family kinases (SFKs) and produces inositol 1,4,5-triphosphate (InsP3) from phosphatidy
Externí odkaz:
https://doaj.org/article/29ed39e31ccc47c68fe3da67de62d33d
Autor:
Myunghwan Ahn, Seung Eun Park, Jiyeon Choi, Jiahn Choi, Doyoung Choi, Dongju An, Hayoung Jeon, Soowhan Oh, Kiho Lee, Jaehoon Kim, Jaebong Jang, Seyun Kim, Youngjoo Byun
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Inositol polyphosphates (IPs) are a group of inositol metabolites that act as secondary messengers for external signalling cues. They play various physiological roles such as insulin release, telomere length maintenance, cell metabolism, and aging. I
Externí odkaz:
https://doaj.org/article/421f0a3bcae2478599ec89915af3be88
Autor:
Tae Gab Ha, Seyun Kim
Publikováno v:
AIMS Mathematics, Vol 8, Iss 5, Pp 10513-10528 (2023)
This paper is concerned with the wave equation having a nonlinear distributed delay. First, we prove the local existence of the solutions by using the semigroup theory, where the source term is globally Lipschitz. Next, we establish the global existe
Externí odkaz:
https://doaj.org/article/3de05df70eef4a5bab2320974bcf9b61
Publikováno v:
Animal Cells and Systems, Vol 26, Iss 6, Pp 254-265 (2022)
ABSTRACTNatural products (NPs) have greatly contributed to the development of novel treatments for human diseases such as cancer, metabolic disorders, and infections. Compared to synthetic chemical compounds, primary and secondary metabolites from me
Externí odkaz:
https://doaj.org/article/03123fea2c264c38967525dd3179e43c
Autor:
Youjin Oh, Eun-Seon Yoo, Sang Hyeon Ju, Eunha Kim, Seulgi Lee, Seyun Kim, Kevin Wickman, Jong-Woo Sohn
Publikováno v:
PLoS Biology, Vol 21, Iss 8, p e3002252 (2023)
It is well known that the neuropeptide Y (NPY)/agouti-related peptide (AgRP) neurons increase appetite and decrease thermogenesis. Previous studies demonstrated that optogenetic and/or chemogenetic manipulations of NPY/AgRP neuronal activity alter fo
Externí odkaz:
https://doaj.org/article/7d0ef672eebf4fadb1b0eb0244cebc5d
Autor:
Boah Lee, Seung Ju Park, Seulgi Lee, Jinwook Lee, Eunbeol Lee, Eun-Seon Yoo, Won-Suk Chung, Jong-Woo Sohn, Byung-Chul Oh, Seyun Kim
Publikováno v:
Cell Death and Disease, Vol 13, Iss 7, Pp 1-14 (2022)
Abstract Autophagy is a biological process that maintains cellular homeostasis and regulates the internal cellular environment. Hyperactivating autophagy to trigger cell death has been a suggested therapeutic strategy for cancer treatment. Mechanisti
Externí odkaz:
https://doaj.org/article/9054af44fd03415eaeb6df3aad49c4bd
Autor:
Seung Eun Park, Dongeun Lee, Jae Woong Jeong, Su-Hyung Lee, Seung Ju Park, Jaeseung Ryu, Se Kyu Oh, Hanseul Yang, Sungsoon Fang, Seyun Kim
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 14, Iss 6, Pp 1235-1256 (2022)
Background & Aims: Inositol polyphosphate multikinase (IPMK), an essential enzyme for inositol phosphate metabolism, has been known to mediate major biological events such as growth. Recent studies have identified single-nucleotide polymorphisms in t
Externí odkaz:
https://doaj.org/article/be5800e75f4f485a8e6f418cc94060e3
Autor:
Seulgi Lee, Bernie Byeonghoon Park, Hongmok Kwon, Vitchan Kim, Jang Su Jeon, Rowoon Lee, Milan Subedi, Taehyeong Lim, Hyunsoo Ha, Dongju An, Jaehoon Kim, Donghak Kim, Sang Kyum Kim, Seyun Kim, Youngjoo Byun
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 269-279 (2022)
Inositol hexakisphosphate kinase (IP6K) is an important mammalian enzyme involved in various biological processes such as insulin signalling and blood clotting. Recent analyses on drug metabolism and pharmacokinetic properties on TNP (N2-(m-trifluoro
Externí odkaz:
https://doaj.org/article/b92d8702f213451b962add5ca26a8351
Publikováno v:
Animal Cells and Systems, Vol 0, Iss 0, Pp 1-9 (2022)
A family of inositol hexakisphosphate kinases (IP6Ks) catalyzes the production of inositol pyrophosphate IP7 (5-diphosphoinositolpentakisphosphate) which is known to modulate various biological events such as cell growth. While targeting IP6K1 in var
Externí odkaz:
https://doaj.org/article/6a7bd8be44204487bbffda2266156b0f
Autor:
Hyoungjoon Ahn, Jong Seong Roh, Seulgi Lee, Jiyoon Beon, Beomgu Lee, Dong Hyun Sohn, Seyun Kim
Publikováno v:
Animal Cells and Systems, Vol 25, Iss 4, Pp 219-226 (2021)
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by widespread joint inflammation, which leads to joint damage, disability, and mortality. Among the several types of immune cells, myeloid cells such as macrophages are critical
Externí odkaz:
https://doaj.org/article/c30870262074448d99494e3cc32b421f