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Dysregulation of type 2 innate lymphoid cells and TH2 cells impairs pollutant-induced allergic airway responses

Autor: De Grove, Katrien C., Provoost, Sharen, Hendriks, Rudi W., McKenzie, Andrew N.J., Seys, Leen J.M., Kumar, Smitha, Maes, Tania, Brusselle, Guy G., Joos, Guy F.

Publikováno v: In The Journal of Allergy and Clinical Immunology January 2017 139(1):246-257

TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C

Autor: MIS-C Clinicians, Hoste, Levi, Roels, Lisa, Naesens, Leslie, Bosteels, Victor, Vanhee, Stijn, Dupont, Sam, Bosteels, Cedric, Browaeys, Robin, Vandamme, Niels, Verstaen, Kevin, Roels, Jana, Van Damme, Karel F A, Maes, Bastiaan, De Leeuw, Elisabeth, Declercq, Jozefien, Aegerter, Helena, Seys, Leen, Smole, Ursula, De Prijck, Sofie, Vanheerswynghels, Manon, Claes, Karlien, Debacker, Veronique, Van Isterdael, Gert, Backers, Lynn, Claes, Kathleen B M, Bastard, Paul, Jouanguy, Emmanuelle, Zhang, Shen-Ying, Mets, Gilles, Dehoorne, Joke, Vandekerckhove, Kristof, Schelstraete, Petra, Willems, Jef, Stordeur, Patrick, Janssens, Sophie, Beyaert, Rudi, Saeys, Yvan, Casanova, Jean-Laurent, Lambrecht, Bart N, Haerynck, Filomeen, Tavernier, Simon J, Daelemans, Siel

Publikováno v: The Journal of Experimental Medicine
Journal of Experimental Medicine, 219(2):e20211381. Rockefeller University Press
JOURNAL OF EXPERIMENTAL MEDICINE

MIS-C is a novel immunodysregulation syndrome in children with a history of SARS-CoV-2 infection. This study employs a multi-omics approach to explore its immunopathogenesis. The authors show that IFNγ-mediated interactions between T cells, monocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0387779e65569f94f163c8e653bf49
https://doi.org/10.1084/jem.20211381

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DPP4, the MERS coronavirus receptor, is upregulated in lungs of smokers and COPD patients

Autor: Seys, Leen JM, Widagdo, W, Verhamme, Fien M, Kleinjan, Alex, Janssens, Wim, Joos, Guy F, Bracke, Ken R, Haagmans, Bart L, Brusselle, Guy G

Middle East respiratory syndrome coronavirus (MERS-CoV) causes pneumonia with a relatively high case fatality rate in humans. Smokers and chronic obstructive pulmonary disease (COPD) patients have been reported to be more susceptible to MERS-CoV infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1131::17fcc21f20a33d602595d86ef7522163
https://academic.oup.com/cid/article-lookup/doi/10.1093/cid/cix741