Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Seyoum Ayehunie"'
Autor:
J.J. Patten, Patrick T. Keiser, Deisy Morselli-Gysi, Giulia Menichetti, Hiroyuki Mori, Callie J. Donahue, Xiao Gan, Italo do Valle, Kathleen Geoghegan-Barek, Manu Anantpadma, RuthMabel Boytz, Jacob L. Berrigan, Sarah H. Stubbs, Tess Ayazika, Colin O’Leary, Sallieu Jalloh, Florence Wagner, Seyoum Ayehunie, Stephen J. Elledge, Deborah Anderson, Joseph Loscalzo, Marinka Zitnik, Suryaram Gummuluru, Mark N. Namchuk, Albert-László Barabási, Robert A. Davey
Publikováno v:
iScience, Vol 25, Iss 9, Pp 104925- (2022)
Summary: Pharmacologically active compounds with known biological targets were evaluated for inhibition of SARS-CoV-2 infection in cell and tissue models to help identify potent classes of active small molecules and to better understand host-virus in
Externí odkaz:
https://doaj.org/article/068bfd3f57e5455390b1fab422a6998a
Autor:
David Tyssen, Anna C. Hearps, Kalyani Guntur, Lindi Masson, Simon Cook, Simon E. Moulton, Jacques Ravel, Catriona S. Bradshaw, Seyoum Ayehunie, Gilda Tachedjian
Publikováno v:
Frontiers in Reproductive Health, Vol 4 (2022)
The vaginal microbiome influences a wide range of health outcomes in women, where a microbiome dominated by Lactobacillus spp. is considered optimal and associated with reduced risk of pre-term birth and acquisition of sexually transmitted infections
Externí odkaz:
https://doaj.org/article/f729ddbc875949eda849d2ea7651b75b
Publikováno v:
Toxicology Reports, Vol 5, Iss , Pp 134-140 (2018)
Most of the widely used vaginal lubricants in the U.S. and Europe are strongly hyperosmolal, formulated with high concentrations of glycerol, propylene glycol, polyquaternary compounds or other ingredients that make these lubricants 4 to 30 times the
Externí odkaz:
https://doaj.org/article/9919028e464b4cdbaadc8f8ee10a7d92
Autor:
Hiroyuki Mori, Patrick T Keiser, Marinka Zitnik, Xiao Gan, Florence F. Wagner, Giulia Menichetti, Manu Anantpadma, Albert-László Barabási, Deborah J. Anderson, Robert A. Davey, Jacob Berrigan, Callie J Donahue, Suryaram Gummuluru, Italo Faria do Valle, Kirabo Tess Ayazika, Mark N. Namchuk, J. J. Patten, Sallieu Chernoh Jalloh, Joseph Loscalzo, Deisy Morselli Gysi, Kathleen Geoghegan-Barek, Seyoum Ayehunie
Publikováno v:
bioRxiv
The SARS-CoV-2 pandemic has caused widespread illness, loss of life, and socioeconomic disruption that is unlikely to resolve until vaccines are widely adopted, and effective therapeutic treatments become established. Here, a well curated and annotat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acd33f07b555b0c31288eb17d4a7e27
https://europepmc.org/articles/PMC8077576/
https://europepmc.org/articles/PMC8077576/
Autor:
Pierre Llanos, Alexander Armento, Zachary Stevens, Seyoum Ayehunie, Mitchell Klausner, Michelle Debatis, Timothy D. Landry, Hailey Scott, Jan Markus
Publikováno v:
In Vitro Cellular & Developmental Biology. Animal
The gastrointestinal tract (GIT), in particular, the small intestine, plays a significant role in food digestion, fluid and electrolyte transport, drug absorption and metabolism, and nutrient uptake. As the longest portion of the GIT, the small intes
Autor:
Carmen Pin, Allison Laura Choy, Kim Maratea, Zachary Stevens, Cortni Dick, Seyoum Ayehunie, Deb Snow, Timothy D. Landry, Herb Barthlow, Matthew F. Peters, A. Armento, Matthew Wagoner, Clay W Scott
Publikováno v:
Toxicological Sciences
Drug-induced gastrointestinal toxicities (GITs) rank among the most common clinical side effects. Preclinical efforts to reduce incidence are limited by inadequate predictivity of in vitro assays. Recent breakthroughs in in vitro culture methods supp
Publikováno v:
Toxicology Reports, Vol 5, Iss, Pp 134-140 (2018)
Toxicology Reports
Toxicology Reports
Most of the widely used vaginal lubricants in the U.S. and Europe are strongly hyperosmolal, formulated with high concentrations of glycerol, propylene glycol, polyquaternary compounds or other ingredients that make these lubricants 4 to 30 times the
Publikováno v:
Toxicology Letters. 350:S232
Autor:
Yun Zhao, Hans Christian Reinecker, James R. Birtley, Beth A. McCormick, Lawrence J. Stern, Karen L. Mumy, Ana Maldonado-Contreras, Erik J. Boll, Juan Toscano, Seyoum Ayehunie
Publikováno v:
Gut Microbes. 8:544-560
Shigella is unique among enteric pathogens, as it invades colonic epithelia through the basolateral pole. Therefore, it has evolved the ability to breach the intestinal epithelial barrier to deploy an arsenal of effector proteins, which permits bacte
Autor:
Seyoum Ayehunie, Mario Pesenti, Giuseppe Firpo, Paolo Buratti, Alessandra Marrella, Helena Kandarova, Jan Markus, Silvia Scaglione, Timothy Landry, Maurizio Aiello
Publikováno v:
ALTEX.
Intestinal permeability is crucial in regulating the bioavailability and, consequently, the biological effects of drugs and compounds. However, systematic and quantitative studies of the absorption of molecules are quite limited due to a lack of reli