Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Seyler, David"'
Autor:
Goldstein, Keith M., Seyler, David E., Durand, Philippe, Perrard, Marie-Hélène, Baker, Thomas K.
Publikováno v:
In Reproductive Toxicology April 2016 60:92-103
Autor:
Thomas K. Baker, Marie-Hélène Perrard, Keith M. Goldstein, Seyler David Edward, Philippe Durand
Publikováno v:
Reproductive Toxicology
Reproductive Toxicology, Elsevier, 2016, 60, pp.92-103. ⟨10.1016/j.reprotox.2016.01.003⟩
Reproductive Toxicology, 2016, 60, pp.92-103. ⟨10.1016/j.reprotox.2016.01.003⟩
Reproductive Toxicology, Elsevier, 2016, 60, pp.92-103. ⟨10.1016/j.reprotox.2016.01.003⟩
Reproductive Toxicology, 2016, 60, pp.92-103. ⟨10.1016/j.reprotox.2016.01.003⟩
Due to the complex physiology of the testes, in vitro models have been largely unsuccessful at modeling testicular toxicity in vivo. We conducted a pilot study to evaluate the utility of the Durand ex vivo rat seminiferous tubule culture model [1-3]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57de1c74ea512e3f71f9761641c195bc
https://hal.archives-ouvertes.fr/hal-02870448
https://hal.archives-ouvertes.fr/hal-02870448
Autor:
Gordon B. Cutler, Jeffrey Alan Dodge, Devanarayan Viswanath, Mark L. Heiman, Karen Leigh Cox, Seyler David Edward, Anita F. Wilmot, Henry Uhlman Bryant, John J. Osborne, M. Joni Keaton
Publikováno v:
Drug Development Research. 49:260-265
Growth hormone (GH) release involves interaction of somatostatin and an endogenous GH secretagogue (GHS) on the hypothalamus. GH causes release of IGF-1, which acts by negative feedback to restrain subsequent GH release. GH secretagogues produce incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a6b9368a14407607ccbe01196d597d6
https://doi.org/10.1002/1098-2299(200004)49:4<260::aid-ddr5>3.0.co
https://doi.org/10.1002/1098-2299(200004)49:4<260::aid-ddr5>3.0.co
Autor:
Robert H. Foote, Steven M. Schrader, Susan L. Makris, M. E. Hurtt, Sally D. Perreault, K. A. Treinen, Eric D. Clegg, Robert E. Chapin, L. D. Wise, Lori A. Dostal, J. Seed, R. Sprando, Seyler David Edward, Gary R. Klinefelter, D. N. R. Veeramachaneni
Publikováno v:
Reproductive Toxicology. 10:237-244
Reproductive toxicity studies are increasingly including assessments of sperm parameters including motility, morphology, and counts. While these assessments can provide valuable information for the determination of potential reproductive toxicity, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1228c4c0a94fc77e98aa4a4625e53d30
https://doi.org/10.1016/0890-6238(96)00028-7
https://doi.org/10.1016/0890-6238(96)00028-7
Developmental Toxicity of Amesergide Administered by Gavage to CD Rats and New Zealand White Rabbits
Publikováno v:
Fundamental and Applied Toxicology. 27:247-251
Amesergide is a selective serotonin 5-HTIC/2 receptor antagonist being developed for the treatment of depression. The potential developmental toxicity of amesergide was evaluated in CD rats and New Zealand white rabbits. Pregnant rats and rabbits wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e5f27bdbbb796c53d0db720e2809c4
https://doi.org/10.1006/faat.1995.1130
https://doi.org/10.1006/faat.1995.1130
Publikováno v:
Drug Development Research. 31:220-227
The chronic toxicity of amesergide, a selective (5HT2/5HT1c) serotonin antagonist, was evaluated in rhesus monkeys given daily nasogastric doses of 0, 5, 10, or 22.5 mg/kg for 1 year. An initial high dose of 25 mg/kg was reduced after approximately 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78a21516ae5173ae235b0b207d88155c
https://doi.org/10.1002/ddr.430310309
https://doi.org/10.1002/ddr.430310309
Publikováno v:
Reproductive Toxicology. 7:607-612
Amesergide, a serotonin (5-HT2) antagonist intended to treat depression, was administered orally to female CD rats (20/group) at doses of 0, 3, 10, or 30 mg/kg to evaluate effects on mating, fertility, litter size, live birth index (100 x total liveb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca2969f481d679909134983cc27d7c9
https://doi.org/10.1016/0890-6238(93)90037-8
https://doi.org/10.1016/0890-6238(93)90037-8
Publikováno v:
Drug Development Research. 36:43-45
Raloxifene is a selective estrogen receptor modulator known to have antiestrogenic effects on uterine tissue. In this study, the effects of raloxifene on uterine explant growth were evaluated in rats. Rats were ovariectomized, implanted with an estra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5218e74a32fc11d8473b1f612efc17c
https://doi.org/10.1002/ddr.430360107
https://doi.org/10.1002/ddr.430360107
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 8(3)
alpha-Chlorohydrin (ACH) was administered to rats in a short-term male reproductive toxicity study to examine the usefulness of the method and to provide reference data with a substance that is known to elicit adverse effects on both sperm production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b180aec45cd9b8ea011306639932da4
https://pubmed.ncbi.nlm.nih.gov/8075513
https://pubmed.ncbi.nlm.nih.gov/8075513
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