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Autor:
Seyfarth, Jürgen Enczmann, Vera Balz, Maximilian Hoffmann, Sebastian Kummer, Christina Reinauer, Carsten Döing, Katharina Förtsch, Alena Welters, Ertan Mayatepek, Thomas Meissner, Marc Jacobsen, Julia
Publikováno v:
Genes; Volume 12; Issue 12; Pages: 1879
The highest genetic type 1 diabetes risk is conferred by HLA class II haplotypes defined by alleles at the HLA-DR and -DQ loci. The combination of HLA-DQA1*03:01 and DQB1*03:02 alleles (summarized as ‘HLA-DQ8′) is reported to be among the two mos