Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Seyeon Bae"'
Autor:
Haemin Kim, In Ah Choi, Akio Umemoto, Seyeon Bae, Kaichi Kaneko, Masataka Mizuno, Eugenia Giannopoulou, Tania Pannellini, Liang Deng, Kyung-Hyun Park-Min
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-15 (2024)
Abstract Osteoclasts are multinucleated bone-resorbing cells, and their formation is tightly regulated to prevent excessive bone loss. However, the mechanisms by which osteoclast formation is restricted remain incompletely determined. Here, we found
Externí odkaz:
https://doaj.org/article/5eab2e5afb7f4e7eaba7faad73e127a2
Autor:
Se Hwan Mun, Seyeon Bae, Steven Zeng, Brian Oh, Carmen Chai, Matthew Jundong Kim, Haemin Kim, George Kalliolias, Chitra Lekha Dahia, Younseo Oh, Tae-Hwan Kim, Jong Dae Ji, Kyung-Hyun Park-Min
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-11 (2021)
Abstract Osteoclasts are bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathological bone erosion. Macrophage colony stimulating factor (M-CSF) is abundant in rheumatoid arthritis (RA). However, the role of M-CSF
Externí odkaz:
https://doaj.org/article/3a5bddf68ff148bea59fec14bf85d5e3
Autor:
Seyeon Bae, Brian Oh, Jefferson Tsai, Peter Sang Uk Park, Matthew Blake Greenblatt, Eugenia G. Giannopoulou, Kyung-Hyun Park-Min
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Osteoclasts are bone-resorbing cells that undergo extensive changes in morphology throughout their differentiation. Altered osteoclast differentiation and activity lead to changes in pathological bone resorption. The mammalian target of rapamycin (mT
Externí odkaz:
https://doaj.org/article/94ddd12e176541f7acf745405b1c2a85
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151248- (2022)
Osteoclasts are bone resorbing cells that are responsible for physiological and pathological bone resorption. Macrophage colony stimulating factor (M-CSF) binds to the M-CSF receptor (c-FMS) and plays a key role in the differentiation and survival of
Externí odkaz:
https://doaj.org/article/1788ac11e7254bef991cefc2727c169e
Autor:
Takayuki Fujii, Koichi Murata, Se-Hwan Mun, Seyeon Bae, Ye Ji Lee, Tannia Pannellini, Kyuho Kang, David Oliver, Kyung-Hyun Park-Min, Lionel B. Ivashkiv
Publikováno v:
Bone Research, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Osteoporosis is a metabolic bone disease with dysregulated coupling between bone resorption and bone formation, which results in decreased bone mineral density. The MEF2C locus, which encodes the transcription factor MADS box transcription e
Externí odkaz:
https://doaj.org/article/3aab1574f2b24004abef962903b45aef
Autor:
Seyeon Bae, Peter Sang Uk Park, Yeji Lee, Se Hwan Mun, Eugenia Giannopoulou, Takayuki Fujii, Kelvin P. Lee, Sara Nunes Violante, Justin R. Cross, Kyung-Hyun Park-Min
Publikováno v:
Cell Reports, Vol 35, Iss 11, Pp 109264- (2021)
Summary: MYC activates different metabolic programs in a cell-type- and cell-status-dependent manner. However, the role of MYC in inflammatory macrophages has not yet been determined. Metabolic and molecular analyses reveal that MYC, but not hypoxia
Externí odkaz:
https://doaj.org/article/f1316364c7fb416295e88be27e4869c4
Autor:
Kyuho Kang, Mahesh Bachu, Sung Ho Park, Keunsoo Kang, Seyeon Bae, Kyung-Hyun Park-Min, Lionel B. Ivashkiv
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Macrophage activation is synergistically controlled by lipopolysaccharide (LPS) and interferon-γ (IFN-γ). Here the authors show that IFN-γ promotes macrophage activation not only by activating STAT1-dependent genes, but also by suppressing STAT3-d
Externí odkaz:
https://doaj.org/article/a631a2760ed54421b4271c48a107d9ac
Autor:
Kyun-Do Kim, Seyeon Bae, Tara Capece, Hristina Nedelkovska, Rafael G. de Rubio, Alan V. Smrcka, Chang-Duk Jun, Woojin Jung, Byeonghak Park, Tae-il Kim, Minsoo Kim
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Regulatory T cells (Tregs) promote immune suppression in the tumour. Here, the authors show that Tregs suppress cytotoxic T lymphocyte (CTL) activity by impairing Ca2+ signalling and that adoptive transfer of CTLs engineered with an optogenetic contr
Externí odkaz:
https://doaj.org/article/eaff6961123b44e39ab2cbba3d2edb63
Publikováno v:
Cells, Vol 9, Iss 9, p 2133 (2020)
Osteoclasts are the sole bone-resorbing cells that play an essential role in homeostatic bone remodeling and pathogenic bone destruction such as inflammatory arthritis. Pharmacologically targeting osteoclasts has been a promising approach to alleviat
Externí odkaz:
https://doaj.org/article/e05b75a024394472afe5d098174e9388
Autor:
Hyemin Kim, Yejin Kim, Seyeon Bae, Joo Myoung Kong, Jiwon Choi, Mirim Jang, Jiyea Choi, Jun-Man Hong, Young-Il Hwang, Jae Seung Kang, Wang Jae Lee
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125742 (2015)
It has recently been reported that the CD40-CD40 ligand (CD40L) interaction is important in Th17 development. In addition, transforming growth factor-beta (TGF-β) promotes tumorigenesis as an immunosuppressive cytokine and is crucial in the developm
Externí odkaz:
https://doaj.org/article/556961b2bc34477a96f0eaa0f4c18209