Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Seyed Amirhossein Tabatabaei"'
Autor:
Farnaz Sani, Shabnam Shojaei, Seyed Amirhossein Tabatabaei, Mohammadhossein Khorraminejad-Shirazi, Mona Latifi, Mahsa Sani, Negar Azarpira
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Chimeric antigen receptor (CAR)-T cell adoptive immunotherapy is a promising cancer treatment that uses genetically engineered T cells to attack tumors. However, this therapy can have some adverse effects. CAR-T cell-derived exosomes are a p
Externí odkaz:
https://doaj.org/article/d2f42e61983a4c24bb1a10a495f8242a
Autor:
Jordan S.F. Chan, Seyed Amirhossein Tabatabaei Dakhili, Maria Areli Lorenzana-Carrillo, Keshav Gopal, Serena M. Pulente, Amanda A. Greenwell, Kunyan Yang, Christina T. Saed, Magnus J. Stenlund, Sally R. Ferrari, Indiresh A. Mangra-Bala, Tanin Shafaati, Rakesh K. Bhat, Farah Eaton, Michael Overduin, Sebastian Beck Jørgensen, Gregory R. Steinberg, Erin E. Mulvihill, Gopinath Sutendra, John R. Ussher
Publikováno v:
Cell Reports, Vol 43, Iss 8, Pp 114573- (2024)
Summary: Growth differentiation factor 15 (GDF15) is a peptide with utility in obesity, as it decreases appetite and promotes weight loss. Because obesity increases the risk for type 2 diabetes (T2D) and cardiovascular disease, it is imperative to un
Externí odkaz:
https://doaj.org/article/8e982b3f2425453094ab8152492fec0a
Autor:
Amanda A. Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Cory S. Wagg, Christina T. Saed, Jordan S.F. Chan, Kunyan Yang, Indiresh A. Mangra‐Bala, Magnus J. Stenlund, Farah Eaton, Keshav Gopal, Jason R.B. Dyck, Gary D. Lopaschuk, John R. Ussher
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 7 (2024)
Externí odkaz:
https://doaj.org/article/b3e4aaaa3d6c48c5ba50d1495bac3ac6
Autor:
Keshav Gopal, Qutuba G. Karwi, Seyed Amirhossein Tabatabaei Dakhili, Cory S. Wagg, Liyan Zhang, Qiuyu Sun, Christina T. Saed, Sai Panidarapu, Riccardo Perfetti, Ravichandran Ramasamy, John R. Ussher, Gary D. Lopaschuk
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Cardiovascular diseases, including diabetic cardiomyopathy, are major causes of death in people with type 2 diabetes. Aldose reductase activity is enhanced in hyperglycemic conditions, leading to altered cardiac energy metabolism
Externí odkaz:
https://doaj.org/article/51239f61fe9f4aaa82e566b6c24008f4
Autor:
Amanda A. Greenwell, Seyed Amirhossein Tabatabaei Dakhili, Keshav Gopal, Christina T. Saed, Jordan S. F. Chan, Nick Kazungu Mugabo, Pavel Zhabyeyev, Farah Eaton, Jennifer Kruger, Gavin Y. Oudit, John R. Ussher
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Barth syndrome (BTHS) is a rare genetic disorder due to mutations in the TAFAZZIN gene, leading to impaired maturation of cardiolipin and thereby adversely affecting mitochondrial function and energy metabolism, often resulting in cardiomyopathy. In
Externí odkaz:
https://doaj.org/article/5408c8de8162435f8fa4dc2704c62e07
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Barth Syndrome (BTHS) is a rare X-linked mitochondrial disorder due to mutations in the gene TAFAZZIN, which leads to immature cardiolipin (CL) remodeling and is characterized by the development of cardiomyopathy. The immature CL remodeling in BTHS r
Externí odkaz:
https://doaj.org/article/990200778eb24a91a0a6b34f452f2aff
Autor:
Yongneng Zhang, Sotirios D. Zervopoulos, Aristeidis E. Boukouris, Maria Areli Lorenzana‐Carrillo, Bruno Saleme, Linda Webster, Yongsheng Liu, Alois Haromy, Seyed Amirhossein Tabatabaei Dakhili, John R. Ussher, Gopinath Sutendra, Evangelos D. Michelakis
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 23 (2021)
Background Isolated loss‐of‐function single nucleotide polymorphisms (SNPs) for SIRT3 (a mitochondrial deacetylase) and UCP2 (an atypical uncoupling protein enabling mitochondrial calcium entry) have been associated with both pulmonary arterial h
Externí odkaz:
https://doaj.org/article/a49e84a6a5684a6698b83b6a9fe8c44a
Autor:
Keshav Gopal, Rami Al Batran, Tariq R. Altamimi, Amanda A. Greenwell, Christina T. Saed, Seyed Amirhossein Tabatabaei Dakhili, M. Toni E. Dimaano, Yongneng Zhang, Farah Eaton, Gopinath Sutendra, John R. Ussher
Publikováno v:
Cell Reports, Vol 35, Iss 1, Pp 108935- (2021)
Summary: Type 2 diabetes (T2D) increases the risk for diabetic cardiomyopathy and is characterized by diastolic dysfunction. Myocardial forkhead box O1 (FoxO1) activity is enhanced in T2D and upregulates pyruvate dehydrogenase (PDH) kinase 4 expressi
Externí odkaz:
https://doaj.org/article/c68c21dfb4204bab9f1c90e933d24e88
Autor:
César Sebastian Huerta-García, David J. Pérez, Carlos A. Velázquez-Martínez, Seyed Amirhossein Tabatabaei Dakhili, Antonio Romo-Mancillas, Rafael Castillo, Alicia Hernández-Campos
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 283 (2022)
We report synthesis, characterization, biological evaluation, and molecular-docking studies of 18 thieno[2,3-b]pyridines with a phenylacetamide moiety at position 2, which is disubstituted with F, Cl, Br, or I at position 4, and with electron-withdra
Externí odkaz:
https://doaj.org/article/9b1f37ab697c41fdbe4b1250007097b7
Autor:
Seyed Amirhossein Tabatabaei Dakhili, David Javier Perez, Keshav Gopal, John Reyes Ussher, Carlos Alberto Velázquez Martínez
Publikováno v:
Proceedings, Vol 22, Iss 1, p 58 (2019)
The Forkhead boX M1 (FOXM1) is an essential transcription factor for normal activation of the cell cycle and cell replication. However, increasing evidence suggests that overexpression of this protein correlates with cancer development and poor patie
Externí odkaz:
https://doaj.org/article/7b8cc1d9582647ceb472af5e4b45d56a