Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Seyda Acar"'
Autor:
Vandana S Kushwaha, Seyda Acar, Daniël M Miedema, Dmitry V Denisov, Peter Schall, Erwin J G Peterman
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228930 (2020)
Intraflagellar transport (IFT) in C. elegans chemosensory cilia is an example of functional coordination and cooperation of two motor proteins with distinct motility properties operating together in large groups to transport cargoes: a fast and proce
Externí odkaz:
https://doaj.org/article/1a4bb167ffa24951a7abb199e60a0410
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 224-235 (2018)
Summary: Cilia are built and maintained by intraflagellar transport (IFT), driving IFT trains back and forth along the ciliary axoneme. How IFT brings about the intricate ciliary structure and how this structure affects IFT are not well understood. W
Externí odkaz:
https://doaj.org/article/cb502b0474614ea4862f6872a5d88d3e
Publikováno v:
Cell Reports, Vol 25, Iss 7, Pp 1701-1707.e2 (2018)
Summary: Cilia are microtubule-based sensing hubs that rely on intraflagellar transport (IFT) for their development, maintenance, and function. Kinesin-2 motors transport IFT trains, consisting of IFT proteins and cargo, from ciliary base to tip. The
Externí odkaz:
https://doaj.org/article/68e9524c952442ffbd83a826b66a2bae
Autor:
Daniël M. Miedema, Vandana S. Kushwaha, Dmitry V. Denisov, Seyda Acar, Bernard Nienhuis, Erwin J. G. Peterman, Peter Schall
Publikováno v:
Physical Review X, Vol 7, Iss 4, p 041037 (2017)
Molecular motor proteins fulfill the critical function of transporting organelles and other building blocks along the biopolymer network of the cell’s cytoskeleton, but crowding effects are believed to crucially affect this motor-driven transport d
Externí odkaz:
https://doaj.org/article/554dedee2a4e48d2ab76f18db312ff61
Akademický článek
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Autor:
Broekmans, Seyda Acar, Tornero, Carlos Vendrell, Toonen, Lodewijk, Valls, Mercedes, Erbrink, Rhode, Ronde, Kaila E., Hogewerf, Wytse, Tolsma, Lisette E. D., Seinstra, Renee I., Janssen, Leen L. S., Nollen, Ellen A. A., Valles, Astrid
Publikováno v:
Molecular Therapy, 30(4), 10-10. CELL PRESS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::0c0e981c487cd080f2d9b715296cff4b
https://research.rug.nl/en/publications/6748ce0b-4315-4526-bb79-537abce40ffb
https://research.rug.nl/en/publications/6748ce0b-4315-4526-bb79-537abce40ffb
Autor:
Carlos Vendrell-Tornero, Astrid Vallès, Seyda Acar-Broekmans, Roman Liscak, Cynthia Brouwers, Lieke Paerels, Pavlina Konstantinova, Melvin M. Evers, Jan Motlik, Marina Sogorb-Gonzalez, Jiri Klima, Harald Petry, Bas Blits, Anouk Stam, Roberta Pintauro, Zdenek Starek, Michal Crha, Dušan Urgošík, Valentina Fodale, Bozena Bohuslavova, Alberto Bresciani, Zdenka Ellederova, Sander J. H. van Deventer
Publikováno v:
Science Translational Medicine. 13
Huntingtin (HTT)-lowering therapies hold promise to slow down neurodegeneration in Huntington's disease (HD). Here, we assessed the translatability and long-term durability of recombinant adeno-associated viral vector serotype 5 expressing a microRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8aa2c90ee9aab9e80550bbf801c4451
https://doi.org/10.1126/scitranslmed.abb8920
https://doi.org/10.1126/scitranslmed.abb8920
Autor:
Irena Bočkaj, Anna Moreno Garcia, Pablo de Miguel Herraiz, Sonay Keskin, Vanessa Zancanella, Şeyda Acar Broekmans, Astrid Vallès, Ying Poi Liu, Melvin Evers, Morgane Wartel
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 3, Pp 102307- (2024)
Given that numerous genetic disorders, driven by diverse pathogenic mechanisms, may be amenable to recombinant adeno-associated virus (rAAV)-delivered gene therapies, the sustained innovation of rAAV-based therapeutic modalities is crucial. The progr
Externí odkaz:
https://doaj.org/article/1a25866587ba456692cfabb12dd9d7ec
Publikováno v:
Cell Reports, Vol 25, Iss 7, Pp 1701-1707.e2 (2018)
Mijalkovic, J, van Krugten, J, Oswald, F, Acar, S & Peterman, E J G 2018, ' Single-Molecule Turnarounds of Intraflagellar Transport at the C. elegans Ciliary Tip ', Cell Reports, vol. 25, no. 7, pp. 1701-1707.e2 . https://doi.org/10.1016/j.celrep.2018.10.050
Cell Reports, 25(7), 1701-1707.e2. Cell Press
Mijalkovic, J, van Krugten, J, Oswald, F, Acar, S & Peterman, E J G 2018, ' Single-Molecule Turnarounds of Intraflagellar Transport at the C. elegans Ciliary Tip ', Cell Reports, vol. 25, no. 7, pp. 1701-1707.e2 . https://doi.org/10.1016/j.celrep.2018.10.050
Cell Reports, 25(7), 1701-1707.e2. Cell Press
Summary: Cilia are microtubule-based sensing hubs that rely on intraflagellar transport (IFT) for their development, maintenance, and function. Kinesin-2 motors transport IFT trains, consisting of IFT proteins and cargo, from ciliary base to tip. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b9ccfbf83f3670dcd1232f3413d27b5
http://www.sciencedirect.com/science/article/pii/S2211124718316395
http://www.sciencedirect.com/science/article/pii/S2211124718316395
Autor:
Seyda Acar, Peter Schall, Dmitry Denisov, Erwin J.G. Peterman, Daniël M. Miedema, Vandana S. Kushwaha
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228930 (2020)
PLoS ONE, 15(2):e0228930. Public Library of Science
PLoS ONE
Kushwaha, V S, Acar, S, Miedema, D M, Denisov, D V, Schall, P & Peterman, E J G 2020, ' The crowding dynamics of the motor protein kinesin-II ', PLoS ONE, vol. 15, no. 2, e0228930, pp. 1-16 . https://doi.org/10.1371/journal.pone.0228930
PLoS ONE, 15(2):e0228930, 1-16. Public Library of Science
PLoS ONE, 15(2):e0228930. Public Library of Science
PLoS ONE
Kushwaha, V S, Acar, S, Miedema, D M, Denisov, D V, Schall, P & Peterman, E J G 2020, ' The crowding dynamics of the motor protein kinesin-II ', PLoS ONE, vol. 15, no. 2, e0228930, pp. 1-16 . https://doi.org/10.1371/journal.pone.0228930
PLoS ONE, 15(2):e0228930, 1-16. Public Library of Science
Intraflagellar transport (IFT) in C. elegans chemosensory cilia is an example of functional coordination and cooperation of two motor proteins with distinct motility properties operating together in large groups to transport cargoes: a fast and proce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5209f972a0076e7416bfb41e9fe6c80c
https://doi.org/10.1371/journal.pone.0228930
https://doi.org/10.1371/journal.pone.0228930