Xq22 deletions and correlation with distinct neurological disease traits in females: Further evidence for a contiguous gene syndrome

Autor: Melanie A. Manning, Ping Fang, Julie R. Jones, Patricia A. Wight, Ken Inoue, Feng Zhang, James R. Lupski, Claudia M.B. Carvalho, Angelique Davis-Williams, Sakku Bai Naidu, Andrea Poretti, Soe Mar, Davut Pehlivan, Carly Jornlin, Hadia Hijazi, Fernanda S. Coelho, Xiaofei Song, Pankaj Patyal, Siddharth Srivastava, Claudia Gonzaga-Jauregui, Grace M. Hobson, Jennifer R. Taube, Barbara Torres, Laura Bernardini, Jennifer A. Lee, Michael J. Friez, Thomas Alberico, Andrea Hanson-Kahn, Sau Wai Cheung

Publikováno v: Human Mutation. 41:150-168

Xq22 deletions that encompass PLP1 (Xq22-PLP1-DEL) are notable for variable expressivity of neurological disease traits in females ranging from a mild late-onset form of spastic paraplegia type 2 (MIM# 312920), sometimes associated with skewed X-inac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::423d7100f94d7f74a7d5bf50aa5f936b
https://doi.org/10.1002/humu.23902

Both Male-Biased and Female-Biased Genes Evolve Faster in Fish Genomes

Autor: Liandong Yang, Zhaolei Zhang, Shunping He

Publikováno v: Genome Biology and Evolution

Males and females often display extensive phenotypic differences, and many of these sexual dimorphisms are thought to result from differences between males and females in expression of genes present in both sexes. Sex-biased genes have been shown to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc75838ae466717415635cab489c6675
https://doi.org/10.1093/gbe/evw239

Variation in the X:Autosome Distribution of Male-Biased Genes among Drosophila melanogaster Tissues and Its Relationship with Dosage Compensation

Autor: John Parsch, Ann Kathrin Huylmans

Publikováno v: Genome Biology and Evolution

Genes that are expressed differently between males and females (sex-biased genes) often show a nonrandom distribution in their genomic location, particularly with respect to the autosomes and the X chromosome. Previous studies of Drosophila melanogas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ec26da3617ba46004448f40c2e01c6
http://europepmc.org/articles/PMC4524484

Convergent evolution of Y chromosome gene content in flies

Autor: Doris Bachtrog, Shivani Mahajan

Publikováno v: Mahajan, Shivani; & Bachtrog, Doris. (2017). Convergent evolution of Y chromosome gene content in flies. Nature Communications, 8(1). doi: 10.1038/s41467-017-00653-x. UC Berkeley: UC Berkeley Library. Retrieved from: http://www.escholarship.org/uc/item/8h35g5rn
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications

Sex-chromosomes have formed repeatedly across Diptera from ordinary autosomes, and X-chromosomes mostly conserve their ancestral genes. Y-chromosomes are characterized by abundant gene-loss and an accumulation of repetitive DNA, yet the nature of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4da01a103fe3a9d123e84b3b0f73373
http://www.escholarship.org/uc/item/8h35g5rn

Sex Differences in the Age of Genetics

Autor: Arthur P. Arnold

The field of sexual differentiation of the brain has its roots primarily in reproductive biology, which sought to explain the factors that guided the adaptively different development of two sexes, each of which has specialized roles in reproduction.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48744db3da8bf099d8c4bf872b4754c7
https://doi.org/10.1016/b978-0-12-803592-4.00092-4