Preclinical evaluation of convection-enhanced delivery of liposomal doxorubicin to treat pediatric diffuse intrinsic pontine glioma and thalamic high-grade glioma

Autor: Sewing AC, Lagerweij T, van Vuurden DG, Meel MH, Veringa SJ, Carcaboso AM, Gaillard PJ, Peter Vandertop W, Wesseling P, Noske D, Kaspers GJ, Hulleman E

Publikováno v: JOURNAL OF NEUROSURGERY-PEDIATRICS
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname

OBJECTIVE Pediatric high-grade gliomas (pHGGs) including diffuse intrinsic pontine gliomas (DIPGs) are primary brain tumors with high mortality and morbidity. Because of their poor brain penetrance, systemic chemotherapy regimens have failed to deliv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::3d3e4c1e1061337ee07dca38a8fa32aa
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=11021

Bevacizumab Targeting Diffuse Intrinsic Pontine Glioma: Results of 89Zr-Bevacizumab PET Imaging in Brain Tumor Models.

Autor: Jansen MH; Department of Pediatrics, Pediatric Hematology and Oncology, Cancer Center, Amsterdam, the Netherlands., Lagerweij T; Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands. Department of Neurosurgery VU University Medical Center and Academic Medical Center, Amsterdam, the Netherlands., Sewing AC; Department of Pediatrics, Pediatric Hematology and Oncology, Cancer Center, Amsterdam, the Netherlands. Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands., Vugts DJ; Department of Radiology & Nuclear Medicine VU University Medical Center, Amsterdam, the Netherlands., van Vuurden DG; Department of Pediatrics, Pediatric Hematology and Oncology, Cancer Center, Amsterdam, the Netherlands. Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands., Molthoff CF; Department of Radiology & Nuclear Medicine VU University Medical Center, Amsterdam, the Netherlands., Caretti V; Department of Pediatrics, Pediatric Hematology and Oncology, Cancer Center, Amsterdam, the Netherlands. Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands. Departments of Neurology, Pediatrics and Neurosurgery, Stanford University School of Medicine, Stanford, California., Veringa SJ; Department of Pediatrics, Pediatric Hematology and Oncology, Cancer Center, Amsterdam, the Netherlands. Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands., Petersen N; Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands., Carcaboso AM; Preclinical Therapeutics and Drug Delivery Research Program, Department of Oncology, Hospital Sant Joan de Déu, Barcelona, Spain., Noske DP; Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands. Department of Neurosurgery VU University Medical Center and Academic Medical Center, Amsterdam, the Netherlands., Vandertop WP; Department of Neurosurgery VU University Medical Center and Academic Medical Center, Amsterdam, the Netherlands., Wesseling P; Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands. Department of Pathology VU University Medical Center. Amsterdam, the Netherlands. Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands., van Dongen GA; Department of Radiology & Nuclear Medicine VU University Medical Center, Amsterdam, the Netherlands., Kaspers GJ; Department of Pediatrics, Pediatric Hematology and Oncology, Cancer Center, Amsterdam, the Netherlands., Hulleman E; Department of Pediatrics, Pediatric Hematology and Oncology, Cancer Center, Amsterdam, the Netherlands. Neuro-oncology Research Group Cancer Center, Amsterdam, the Netherlands. e.hulleman@vumc.nl.

Publikováno v: Molecular cancer therapeutics [Mol Cancer Ther] 2016 Sep; Vol. 15 (9), pp. 2166-74. Date of Electronic Publication: 2016 Jun 20.

Human pontine glioma cells can induce murine tumors.

Autor: Caretti V; Departments of Neurology, Neurosurgery and Pediatrics, Stanford University School of Medicine, Stanford, USA, vcaretti@stanford.edu., Sewing AC, Lagerweij T, Schellen P, Bugiani M, Jansen MH, van Vuurden DG, Navis AC, Horsman I, Vandertop WP, Noske DP, Wesseling P, Kaspers GJ, Nazarian J, Vogel H, Hulleman E, Monje M, Wurdinger T

Publikováno v: Acta neuropathologica [Acta Neuropathol] 2014; Vol. 127 (6), pp. 897-909. Date of Electronic Publication: 2014 Apr 29.

Therapeutic hypercapnia prevents bleomycin-induced pulmonary hypertension in neonatal rats by limiting macrophage-derived tumor necrosis factor-α.

Autor: Sewing AC; Physiology and Experimental Medicine Program, Hospital for Sick Children Research Institute, Toronto, Ontario, Canada., Kantores C, Ivanovska J, Lee AH, Masood A, Jain A, McNamara PJ, Tanswell AK, Jankov RP

Publikováno v: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2012 Jul 01; Vol. 303 (1), pp. L75-87. Date of Electronic Publication: 2012 May 11.