Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Sewell Tonya J"'
Autor:
Sam L. Koprak, Carolyn DaSilva, Sewell Tonya J, Mary Jo Staruch, Ramon E. Camacho, Gino Salituro, Francis J. Dumont
Publikováno v:
Immunopharmacology. 44:255-265
Hypothemycin, a resorcylic acid lactone antibiotic, was identified as active in a screen for inhibitors of T cell activation. It was found to inhibit the proliferation of mouse and human T cells stimulated with anti-CD3 mAb+PMA and of human PBMC stim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e1bad61cf8d8e93f53d98bc52e15220
https://doi.org/10.1016/s0162-3109(99)00085-5
https://doi.org/10.1016/s0162-3109(99)00085-5
Autor:
C S Lin, Richard K. Harrison, Francis J. Dumont, Samuel Koprak, V M Kindt, Sewell Tonya J, Mathew J. Wyvratt, Thomas R. Beattie, John Siekierka, Mary-Jo Staruch
Publikováno v:
The Journal of Experimental Medicine
FK-506 inhibits Ca(2+)-dependent transcription of lymphokine genes in T cells, and thereby acts as a powerful immunosuppressant. However, its potential therapeutic applications may be seriously limited by several side effects, including nephrotoxicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d5c380b285dfa2270ab5961edcccde
https://doi.org/10.1084/jem.176.3.751
https://doi.org/10.1084/jem.176.3.751