Mechanistic evaluation of a novel cyclohexenone derivative's functionality against nociception and inflammation: An in-vitro, in-vivo and in-silico approach.

Autor: Khan J; Department of Pharmacy, University of Peshawar, Peshawar, 25120, Pakistan., Ali G; Department of Pharmacy, University of Peshawar, Peshawar, 25120, Pakistan. Electronic address: gowhar_ali@uop.edu.pk., Rashid U; Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Pakistan., Khan R; Institute of Chemical Sciences, University of Peshawar, 25120, Pakistan., Jan MS; Department of Pharmacy, Faculty of Biological Sciences, University of Malakand, Chakdara, 18000 Dir (L), Pakistan., Ullah R; Department of Pharmacy, University of Peshawar, Peshawar, 25120, Pakistan., Ahmad S; Department of Health and Biological Sciences, Abasyn University, Peshawar, 25000, Pakistan., Abbasi SW; Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, 46000, Pakistan., Khan Khalil AA; Department of Biological Sciences, National University of Medical Sciences, Rawalpindi, 46000, Pakistan., Sewell RE; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, CF10 3NB, UK. UK.

Publikováno v: European journal of pharmacology [Eur J Pharmacol] 2021 Jul 05; Vol. 902, pp. 174091. Date of Electronic Publication: 2021 Apr 16.