Zobrazeno 1 - 10
of 376
pro vyhledávání: '"Seward B Rutkove"'
Autor:
Sarbesh R Pandeya, Janice A Nagy, Daniela Riveros, Carson Semple, Rebecca S Taylor, Benjamin Sanchez, Seward B Rutkove
Publikováno v:
PLoS ONE, Vol 16, Iss 10, p e0259071 (2021)
Electrical impedance myography (EIM) using surface techniques has shown promise as a means of diagnosing and tracking disorders affecting muscle and assessing treatment efficacy. However, the relationship between such surface-obtained impedance value
Externí odkaz:
https://doaj.org/article/f720e37e4ce74c58a24921946dd88297
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223265 (2019)
Electrical impedance myography (EIM) is a technique for the assessment of muscle health and composition and has been shown to be sensitive to a variety of muscle pathologies including neurogenic atrophy and connective tissue deposition. However, it h
Externí odkaz:
https://doaj.org/article/8fe2e906971145098008a3771c422ff3
Autor:
Chady H Hakim, Alex Mijailovic, Thais B Lessa, Joan R Coates, Carmen Shin, Seward B Rutkove, Dongsheng Duan
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173557 (2017)
Dystrophin-deficient dogs are by far the best available large animal models for Duchenne muscular dystrophy (DMD), the most common lethal childhood muscle degenerative disease. The use of the canine DMD model in basic disease mechanism research and t
Externí odkaz:
https://doaj.org/article/d0e957bff0ce4e5e9dda60850711d79c
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185614 (2017)
Loss of muscle mass and strength represents one of the most significant contributors to impaired function in older adults. Convenient and non-invasive biomarkers are needed that can readily identify and track age-related muscle change. Previous data
Externí odkaz:
https://doaj.org/article/4ff2fdc992894c799f9420a9ab8b3131
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151415 (2016)
OBJECTIVE:Tools to better evaluate the impact of therapy on nerve and muscle disease are needed. Electrical impedance myography (EIM) is sensitive to neuromuscular disease progression as well as to therapeutic interventions including myostatin inhibi
Externí odkaz:
https://doaj.org/article/e94f7337060743d1bef40e5bf4c2d4ec
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140521 (2015)
OBJECTIVES:Non-invasive and effort independent biomarkers are needed to better assess the effects of drug therapy on healthy muscle and that affected by muscular dystrophy (mdx). Here we evaluated the use of multi-frequency electrical impedance for t
Externí odkaz:
https://doaj.org/article/1ccef6c8678a4491a177fde3deb8c254
Autor:
Jia Li, Tom R Geisbush, William D Arnold, Glenn D Rosen, Phillip G Zaworski, Seward B Rutkove
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e111428 (2014)
OBJECTIVES:There is a need for better, noninvasive quantitative biomarkers for assessing the rate of progression and possible response to therapy in spinal muscular atrophy (SMA). In this study, we compared three electrophysiological measures: compou
Externí odkaz:
https://doaj.org/article/b447b257d2d344159e88b398c2f64ddd
Autor:
Keyuan Ren, Qinglong Wang, Douglas Jiang, Ethan Liu, Julie Alsmaan, Rui Jiang, Seward B. Rutkove, Feng Tian
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease, is characterized by progressive motor neuron degeneration, leading to widespread weakness and respiratory failure. While a variety of mechanisms have been proposed as cause
Externí odkaz:
https://doaj.org/article/b51fdb7f1fff4c0c9d7303e53643858d
Autor:
Megan E. Rosa‐Caldwell, Lauren Breithaupt, Ursula B. Kaiser, Eliza Garland, Sheridyn Pinkham, Madisyn Hancock, Sophie L. Jalkut, Seward B. Rutkove
Publikováno v:
Physiological Reports, Vol 12, Iss 12, Pp n/a-n/a (2024)
Abstract Current rodent models of anorexia nervosa (AN) often have accelerated weight loss that often do not allow for investigation of physiological ramifications of prolonged low weight status characteristic of AN. The purpose of this project was t
Externí odkaz:
https://doaj.org/article/f872ac7fe8124790a1838f1bc2019526
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65976 (2013)
To compare electrical impedance myography (EIM) 50 kHz phase to weight, motor score, paw grip endurance (PGE), CMAP amplitude, and MUNE for the identification of disease progression and the effect of riluzole in the SOD1 G93A mouse.Twenty-three anima
Externí odkaz:
https://doaj.org/article/b29fc8c461c74160996c458c188c4d88