Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Sew Peak-Chew"'
Autor:
Yang Yang, Alexey G. Murzin, Sew Peak-Chew, Catarina Franco, Holly J. Garringer, Kathy L. Newell, Bernardino Ghetti, Michel Goedert, Sjors H. W. Scheres
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-11 (2023)
Abstract We used electron cryo-microscopy (cryo-EM) to determine the structures of Aβ40 filaments from the leptomeninges of individuals with Alzheimer’s disease and cerebral amyloid angiopathy. In agreement with previously reported structures, whi
Externí odkaz:
https://doaj.org/article/3b5c675531d343d79d122581505c8219
Autor:
Tammaryn Lashley, Maria-Armineh Tossounian, Neve Costello Heaven, Samantha Wallworth, Sew Peak-Chew, Aaron Bradshaw, J. Mark Cooper, Rohan de Silva, Surjit Kaila Srai, Oksana Malanchuk, Valeriy Filonenko, Margreet B. Koopman, Stefan G. D. Rüdiger, Mark Skehel, Ivan Gout
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 15 (2021)
Alzheimer’s disease (AD) is a neurodegenerative disorder, accounting for at least two-thirds of dementia cases. A combination of genetic, epigenetic and environmental triggers is widely accepted to be responsible for the onset and development of AD
Externí odkaz:
https://doaj.org/article/b23506173cea4a9a8b88bed62e3c2af3
Autor:
Yugo Tsuchiya, Dominic P. Byrne, Selena G. Burgess, Jenny Bormann, Jovana Baković, Yueyang Huang, Alexander Zhyvoloup, Bess Yi Kun Yu, Sew Peak-Chew, Trang Tran, Fiona Bellany, Alethea B. Tabor, AW Edith Chan, Lalitha Guruprasad, Oleg Garifulin, Valeriy Filonenko, Matthias Vonderach, Samantha Ferries, Claire E. Eyers, John Carroll, Mark Skehel, Richard Bayliss, Patrick A. Eyers, Ivan Gout
Publikováno v:
Redox Biology, Vol 28, Iss , Pp - (2020)
Aurora A kinase is a master mitotic regulator whose functions are controlled by several regulatory interactions and post-translational modifications. It is frequently dysregulated in cancer, making Aurora A inhibition a very attractive antitumor targ
Externí odkaz:
https://doaj.org/article/0b4c8d09c14d4fdebd87d9bb7b34b081
Autor:
Rachel S. Edgar, Andrew D. Beale, Estere Seinkmane, Edward A. Hayter, Alison J. Inglis, Joseph L. Watson, Emmanuel Derivery, Thomas Pons, Sew Peak Chew, Stefan Matile, Aiwei Zeng, Jason Day, Alessandra Stangherlin, Nicolas Lequeux, Rebecca M. Voorhees, Gerben van Ooijen, Silvia Barbiero, John S. O’Neill, Peter Newham, David C S Wong, Marrit Putker, Eline Bartolami, Alina Guna, David A. Bechtold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Nature Communications
Nature Communications
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic potential exerted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0acfb0784324a2a1b275d73b8240e3
http://hdl.handle.net/10044/1/104009
http://hdl.handle.net/10044/1/104009
Autor:
Emmanuel Derivery, Alison J. Inglis, Thomas Pons, Rachel S. Edgar, Joseph L. Watson, Sew Peak Chew, Estere Seinkmane, Aiwei Zeng, Jason Day, Alessandra Stangherlin, Silvia Barbiero, Nicolas Lequeux, Andrew D. Beale, Peter Newham, Stefan Matile, Gerben van Ooijen, Edward A. Hayter, John S. O’Neill, David C S Wong, Eline Bartolami, Alina Guna, David A. Bechtold, Rebecca M. Voorhees
Between 6-20% of the cellular proteome is under circadian control to tune cell function with cycles of environmental change. For cell viability, and to maintain volume within narrow limits, the osmotic pressure exerted by changes in the soluble prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef0a982c18a5abba57f5c0969abaf2fd
https://doi.org/10.1101/2020.05.28.118398
https://doi.org/10.1101/2020.05.28.118398
Autor:
David C.S. Wong, Estere Seinkmane, Alessandra Stangherlin, Aiwei Zeng, Nina M. Rzechorzek, Andrew D. Beale, Jason Day, Martin Reed, Sew Peak Chew, Christine T. Styles, Rachel S. Edgar, Marrit Putker, John S. O’Neill
The daily organisation of most mammalian cellular functions is attributed to circadian regulation of clock-controlled protein expression, driven by daily cycles of CRYPTOCHROME-dependent transcriptional feedback repression. To test this, we compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7e7161e760831fb6711d242e3bbc496
https://doi.org/10.1101/2020.05.16.099556
https://doi.org/10.1101/2020.05.16.099556
Autor:
Sangeun Kim, Laura Palmer, Ivan Gout, Mark Skehel, Giacomo Stanzani, Daniel Silva, Oksana Malanchuk, Bess Yi Kun Yu, Sew Peak Chew, Jovana Baković, Sun-Hee Ahn, Valeriy Filonenko, Tae-Hoon Lee, Lujain Aloum, Michael R. Duchen, Mervyn Singer
Publikováno v:
Molecular and Cellular Biochemistry
Peroxiredoxins (Prdxs) are antioxidant enzymes that catalyse the breakdown of peroxides and regulate redox activity in the cell. Peroxiredoxin 5 (Prdx5) is a unique member of Prdxs, which displays a wider subcellular distribution and substrate specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cca193ad2eafee39ad4c559214f0dc26
https://pubmed.ncbi.nlm.nih.gov/31375973
https://pubmed.ncbi.nlm.nih.gov/31375973
Publikováno v:
Molecular Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=r3c4b2081b22::ad50bcf2fdc5175fc4bd8f8a2305e105
Publikováno v:
Molecular Biology of the Cell. 14:625-641
We have used GST pulldowns from A431 cell cytosol to identify three new binding partners for the γ-adaptin appendage: Snx9, ARF GAP1, and a novel ENTH domain-containing protein, epsinR. EpsinR is a highly conserved protein that colocalizes with AP-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::567f06cf500a6dae1ac20bb2dbfe465d
https://doi.org/10.1091/mbc.e02-09-0552
https://doi.org/10.1091/mbc.e02-09-0552
N-Terminal Acetylation of the Neuronal Protein SNAP-25 Is Revealed by the SMI81 Monoclonal Antibody.
Publikováno v:
Biochemistry; 10/13/2009, Vol. 48 Issue 40, p9582-9589, 8p