Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Sevim Tunali"'
Publikováno v:
Volume: 9, Issue: 3 721-728
Journal of the Turkish Chemical Society Section A: Chemistry
Journal of the Turkish Chemical Society Section A: Chemistry
Diabetes mellitus (DM), closely related to diabetic nephropathy, is one of the major public health problems worldwide. Today, with the increasing understanding of the underlying pathophysiology of DM, new oral anti-diabetic treatment strategies are b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d06f65ab4b4f424545c14b33e42d3fb
https://doi.org/10.18596/jotcsa.1071151
https://doi.org/10.18596/jotcsa.1071151
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 36
Diabetes is usually accompanied by increased production of free radicals or impaired antioxidant defenses. The brain is a target tissue of the oxidative attacks caused by diabetes, and there are observed changes in the biochemical parameters of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0196489ee71cfe94e0586d152c166796
https://doi.org/10.1002/jbt.22991
https://doi.org/10.1002/jbt.22991
Autor:
Tülay Bal-Demirci, Ediz Coskun, Refiye Yanardag, Sevim Tunali, Sehnaz Bolkent, Selda Gezginci-Oktayoglu, Bahri Ülküseven
Publikováno v:
Biological Trace Element Research. 199:1515-1523
Vanadium compounds are being investigated as potential therapeutic agents in the treatment of many health problems, primarily diabetes. We aimed to provide the effect of N(1)-4-hydroxysalicylidene-N(4)-salicylidene-S-methyl-isothiosemicarbazidato-oxo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0de93d3c93287894ed20bcfffbd2df0
https://doi.org/10.1007/s12011-020-02269-7
https://doi.org/10.1007/s12011-020-02269-7
Publikováno v:
Toxicology mechanisms and methods. 31(8)
Diabetes mellitus (DM) is chronic and metabolic disorder, which is mainly attributed by hyperglycemia. Vanadium salts and their oxo-complexes have been shown to possess insulin-mimetic and anti-diabetic activities in animal models and diabetic patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e64107643c1c0b1286b49e4fa0f1067
https://pubmed.ncbi.nlm.nih.gov/34240667
https://pubmed.ncbi.nlm.nih.gov/34240667
Publikováno v:
Bulgarian Chemical Communications. 51:159-163
Enzymes are made of protein, that is why they are sensitive molecules and are affected by storage conditions. A small change in enzyme activity during storage may cause a big error in analysis results. The aim of the study was to evaluate the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65c9b6a3e807e6e8ca98a8ac0b7b95e4
https://doi.org/10.34049/bcc.51.2.4536
https://doi.org/10.34049/bcc.51.2.4536
Autor:
Ayse Can, Sehnaz Bolkent, Selda Gezginci-Oktayoglu, Refiye Yanardag, Ertan Celik, Sevim Tunali
The aim of this study was to investigate the cellular mechanisms that cause valproic acid (VPA)-induced liver damage and the therapeutic effect of Vitamin U (Vit U) on these mechanisms. Female Sprague Dawley rats were randomly divided into four group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::457ac3126955e8e3ae2f7a825c2f98d3
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 34
Vitamin U (Vit U) is a novel free-radical scavenger. The protective effect of Vit U on valproic acid (VPA)-induced lung damage was examined. Rats were divided into four groups: control rats; rats given Vit U (50 mg/kg/d, by gavage) for 15 days; rats
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88a8a72af5c46b56b06e0be02972755d
https://doi.org/10.1002/jbt.22602
https://doi.org/10.1002/jbt.22602
Autor:
Sevim, Tunali, Selda, Gezginci-Oktayoglu, Sehnaz, Bolkent, Ediz, Coskun, Tulay, Bal-Demirci, Bahri, Ulkuseven, Refiye, Yanardag
Publikováno v:
Biological trace element research. 199(4)
Vanadium compounds are being investigated as potential therapeutic agents in the treatment of many health problems, primarily diabetes. We aimed to provide the effect of N(1)-4-hydroxysalicylidene-N(4)-salicylidene-S-methyl-isothiosemicarbazidato-oxo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d3d54aadda69e048ced012a3a2ce066b
https://pubmed.ncbi.nlm.nih.gov/32815091
https://pubmed.ncbi.nlm.nih.gov/32815091
Publikováno v:
Journal of food biochemistryREFERENCES.
Valproic acid (VPA; 2-propyl valeric acid) is a potent drug widely used in treating anxiety disorders, migraine as well as epileptic diseases. In the ongoing study chard protective effect was investigated, on the damaged VPA rat brain. Sprague Dawley
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ee870b2d6aa11b06739fa078f95beb0
https://pubmed.ncbi.nlm.nih.gov/32754946
https://pubmed.ncbi.nlm.nih.gov/32754946
Publikováno v:
Volume: 50, Issue: 2 125-130
İstanbul Journal of Pharmacy
İstanbul Journal of Pharmacy
WOS:000569213100009 Background and Aims: Myeloperoxidase (MPO, EC 1.11.2.2) is a vital antimicrobial enzyme, having a crucial role in host defense. Obstructing the activity of MPO is a possible pharmacological approach for the hindrance and managemen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::156b1b77f106d1250435d2fd8bdd6d35
https://doi.org/10.26650/IstanbulJPharm.2020.0017
https://doi.org/10.26650/IstanbulJPharm.2020.0017