Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Sevim Dalkara"'
Autor:
Didem Kart, Burcu Sayoğlu, Ebru Koçak, M. Fahir Acar, Sevim Dalkara, Suat Sari, Zeynep Özdemir, Arzu Karakurt
Publikováno v:
International Microbiology. 24:93-102
Candida infections pose a serious public health threat due to increasing drug resistance. Azoles are first-line antifungal drugs for fungal infections. In this study, we tested an in-house azole collection incorporating naphthalene ring to find hits
Autor:
İrem Bozbey, İnci Selin Doğan, Ebru Koçak, Didem Kart, Zeynep Özdemir, Ahmet Avci, Suat Sari, Suna Sabuncuoğlu, Sevim Dalkara, Selma Saraç, Arzu Karakurt
Publikováno v:
Drug Development Research. 81:1026-1036
Azole antifungal drugs are commonly used in antifungal chemotherapy. Antibacterial effects of some topical antifungals, such as miconazole and econazole, have lately been revealed, which suggests a promising venue in antimicrobial chemotherapy. In th
Publikováno v:
Journal of Research in Pharmacy. 23:952-959
Autor:
Suat, Sari, Suna, Sabuncuoğlu, Ebru, Koçak Aslan, Ahmet, Avci, Didem, Kart, Zeynep, Özdemir, M Fahir, Acar, Burcu, Sayoğlu, M Abdullah, Alagöz, Arzu, Karakurt, Sevim, Dalkara
Publikováno v:
Journal of biomolecular structuredynamics. 40(20)
Azoles are first-line drugs used in fungal infections. Topical antifungals, such as miconazole and econazole, are known to be active against Gram-positive bacteria, which was reported to result from bacterial flavohemoglobin (flavoHb) inhibition. Dua
Autor:
Didem Kart, Naile Öztürk, Suat Sari, F. Betül Kaynak, Arzu Karakurt, Sevim Dalkara, Selma Saraç, Sebnem Essiz, Melis Gencel, Gülce Taşkor
Publikováno v:
European journal of medicinal chemistry. 190
Autor:
Naile Öztürk, Gülce Taşkor, Melis Gencel, Sebnem Essiz, Sevim Dalkara, Didem Kart, Selma Saraç, Suat Sari, F. Betül Kaynak, Arzu Karakurt
Systemic candidiasis is a rampant bloodstream infection ofCandidaspp. andC. albicansis the majorpathogen isolated from infected humans. Azoles, the most common class of antifungals which sufferfrom increasing resistance, and especially intrinsically
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa30c97e5fd41971e3b74e5391ca51f
https://hdl.handle.net/20.500.12469/2829
https://hdl.handle.net/20.500.12469/2829
Publikováno v:
Pharmacological Reports. 70:1116-1123
Currently available antiepileptic drugs offer limited symptomatic treatment and fail to cure more than 30% of the epileptic seizures. (Arylalkyl)azoles are a class of anticonvulsants including nafimidone and loreclezole. Here, we report the design an
Autor:
Selma Saraç, Şebnem Eşsiz Gökhan, Sevim Dalkara, Didem Kart, Suat Sari, Imran Vural, İnci Selin Doğan
Publikováno v:
European Journal of Medicinal Chemistry. 130:124-138
Azole antifungals are potent inhibitors of fungal lanosterol 14 alpha demethylase (CYP51) and have been used for eradication of systemic candidiasis clinically. Herein we report the design synthesis and biological evaluation of a series of 1-phenyl/1
Autor:
Selma Saraç, Suat Sari, Didem Kart, Melis Gencel, İrem Bozbey, Sebnem Essiz, Suna Sabuncuoğlu, Sevim Dalkara, İnci Selin Doğan, Arzu Karakurt, Zeynep Özdemir, Jóhannes Reynisson
Systemic Candida infections pose a serious public health problem with high morbidity and mortality. C. albicans is the major pathogen identified in candidiasis, however non-albicans Candida spp. with antifungal resistance are now more prevalent. Azol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd55af4f144f1fec9a8219bfb3c5cf74
https://hdl.handle.net/20.500.12469/3538
https://hdl.handle.net/20.500.12469/3538
In this study, 15 new oxime ether derivatives were synthesized and their anticonvulsant activities were screened in vivo. The compounds were synthesized by the reaction of various alkyl halides with 1-(2-naphthyl)-2-(1H-imidazol-1-yl)ethanone oxime.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f227ebd59b2e17d3eb58043c7997693d
https://aperta.ulakbim.gov.tr/record/72007
https://aperta.ulakbim.gov.tr/record/72007