Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Sevim AKYÜZ"'
Publikováno v:
Open Journal of Nano. 8:1-9
Ruxolitinib (C17H18N6) is a Janus kinase (JAK) inhibitor that inhibits JAK1, JAK2, and JAK3 and with its tyrosine kinase inhibitor function It is the first drug approved for use in the treatment of myelofibrosis. The possible conformations of the rux
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17a826aa4112f5bb26144573829e3c5c
https://doi.org/10.56171/ojn.1134119
https://doi.org/10.56171/ojn.1134119
Publikováno v:
Volume: 26, Issue: 3 135-142
Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Cyclo(Phe-Phe) dipeptidi Alzheimer hastalığı tedavisinde etkili bir dipeptitdir. Bu çalışmada Cyclo(Phe-Phe) dipeptidinin 3-Boyutlu yapısı teorik konformasyon analizi (TKA) metodu ile belirlenmiştir. Konformasyon analizinde, Ramachandran har
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58d8182a0416ed13ac2a04fd458f7c2
https://doi.org/10.53433/yyufbed.941445
https://doi.org/10.53433/yyufbed.941445
Publikováno v:
Bayburt Üniversitesi Fen Bilimleri Dergisi.
The structural preferences of curcumin (C21H20O6) molecule were analyzed by MMFF method using Spartan06 program and the most stable geometry was determined. To evaluate the effects of curcumin on SARS-CoV-2, the molecular docking studies have been do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::427fa4fbe29a81b93173db939f28461d
https://doi.org/10.55117/bufbd.1138678
https://doi.org/10.55117/bufbd.1138678
Publikováno v:
Yüzüncü Yıl Üniversitesi Fen Bilimleri Enstitüsü Dergisi. 26:80-87
Antimikrobiyal ve antikanser gibi önemli biyolojik aktivitelere sahip olan Cyclo(Trp-Trp) dipeptidinin (C₂₂H₂₀N₄O₂) en düşük enerjili moleküler geometrisi, teorik konformasyon analizi hesabını takiben yapılan Yoğunluk Fonksiyonel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fc7ff461704cdead7b8ad9651339a64
https://doi.org/10.53433/yyufbed.908710
https://doi.org/10.53433/yyufbed.908710
Publikováno v:
Volume: 25, Issue: 2 401-409
Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi
Bu çalışmada HT-29, Hela ve MCF-7 hücre hatlarına karşı antikanser etki gösteren Cyclo(Tyr-Tyr) dipeptidinin olası en kararlı yedi konformasyonu tirozin aminoasilerinin χ yan zincir dihedral açılarına bağlı olarak konformasyon analizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0778e49229600f96c81ca04ff81cf4
https://doi.org/10.19113/sdufenbed.881399
https://doi.org/10.19113/sdufenbed.881399
Publikováno v:
Bulletin of the Chemical Society of Ethiopia. 34:613-623
In this study conformation analysis of seven drugs commonly used in the treatment of COVID-19 was performed. The most stable conformers of the drug molecules were used as initial data for docking analysis. Using the Cavityplus program, the probable m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85cb40488acdfee1333839ce68f768b6
https://doi.org/10.4314/bcse.v34i3.16
https://doi.org/10.4314/bcse.v34i3.16
Publikováno v:
Volume: 8, Issue: 1 11-21
Open Journal of Nano
Open Journal of Nano
The molecular structures of the lowest-energy conformers of donepezil (C24H29NO3), rivastigmine (C14H22N2O2), and galantamine (C17H21NO3), which are extensively used in Alzheimer's disease and other memory disorders, were identified using the Spartan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ce335f676490573fbd79b21891ab17
https://dergipark.org.tr/tr/pub/ojn/issue/72059/1109606
https://dergipark.org.tr/tr/pub/ojn/issue/72059/1109606
Publikováno v:
Volume: 8, Issue: 1 2-8
Open Journal of Nano
Open Journal of Nano
Midostaurin (C35H30N4O4), diğer kemoterapi ajanları ile birlikte bazı akut miyeloid lösemi tiplerini tedavi etmek için kullanılan multi-target kinaz inhibitörüdür. Biyoaktif bir molekülün biyoaktivitesini gösterdiği en kararlı konformer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::295e345da6576822b30b3712a87cc2c1
https://dergipark.org.tr/tr/pub/ojn/issue/72059/1102513
https://dergipark.org.tr/tr/pub/ojn/issue/72059/1102513
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 40:660-672
The theoretically possible most stable conformation of the cyclic dipeptide, which has a significant anticancer activity, was examined by conformational analysis method and then by DFT calculations. With DFT calculations, cyclo(Ala-His) dipeptide was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94af0da5c5875cfccba11fa1f3ecb6f7
https://doi.org/10.1080/07391102.2020.1817150
https://doi.org/10.1080/07391102.2020.1817150
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 39:4212-4224
A new nickel(II) complex was synthesized by using S-propyl-thiosemicarbazide and 2-amino-3,5-dibromobenzaldehyde. The complex, obtained by the template effect of nickel ions, was structurally analysed by experimental and theoretical vibrational spect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3729b3436b4eb20c2d9912d2747bac31
https://doi.org/10.1080/07391102.2020.1775128
https://doi.org/10.1080/07391102.2020.1775128