biAb Mediated Restoration of the Linkage between Dystroglycan and Laminin-211 as a Therapeutic Approach for α-Dystroglycanopathies.

Autor: Gumlaw N; Sanofi, Framingham, MA 01701-9322, USA., Sevigny LM; Sanofi, Framingham, MA 01701-9322, USA. Electronic address: leila.sevigny@sanofi.com., Zhao H; Sanofi, Framingham, MA 01701-9322, USA., Luo Z; Sanofi, Framingham, MA 01701-9322, USA., Bangari DS; Sanofi, Framingham, MA 01701-9322, USA., Masterjohn E; Sanofi, Framingham, MA 01701-9322, USA., Chen Y; Sanofi, Framingham, MA 01701-9322, USA., McDonald B; Sanofi, Framingham, MA 01701-9322, USA., Magnay M; Sanofi, Framingham, MA 01701-9322, USA., Travaline T; Sanofi, Framingham, MA 01701-9322, USA., Yoshida-Moriguchi T; Sanofi, Framingham, MA 01701-9322, USA., Fan W; Sanofi, Framingham, MA 01701-9322, USA., Reczek D; Sanofi, Framingham, MA 01701-9322, USA., Stefano JE; Sanofi, Framingham, MA 01701-9322, USA., Qiu H; Sanofi, Framingham, MA 01701-9322, USA., Beil C; Sanofi, Framingham, MA 01701-9322, USA., Lange C; Sanofi, Framingham, MA 01701-9322, USA., Rao E; Sanofi, Framingham, MA 01701-9322, USA., Lukason M; Sanofi, Framingham, MA 01701-9322, USA., Barry E; Sanofi, Framingham, MA 01701-9322, USA., Brondyk WH; Sanofi, Framingham, MA 01701-9322, USA., Zhu Y; Sanofi, Framingham, MA 01701-9322, USA., Cheng SH; Sanofi, Framingham, MA 01701-9322, USA.

Publikováno v: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2020 Feb 05; Vol. 28 (2), pp. 664-676. Date of Electronic Publication: 2019 Dec 06.

Identification of a human monoclonal antibody to replace equine diphtheria antitoxin for treatment of diphtheria intoxication.

Autor: Sevigny LM; MassBiologics of the University of Massachusetts Medical School, Boston, Massachusetts, USA., Booth BJ, Rowley KJ, Leav BA, Cheslock PS, Garrity KA, Sloan SE, Thomas W Jr, Babcock GJ, Wang Y

Publikováno v: Infection and immunity [Infect Immun] 2013 Nov; Vol. 81 (11), pp. 3992-4000. Date of Electronic Publication: 2013 Aug 12.

Interdicting protease-activated receptor-2-driven inflammation with cell-penetrating pepducins.

Autor: Sevigny LM; Molecular Oncology Research Institute, Tufts University School of Medicine, Boston, MA 02111, USA., Zhang P, Bohm A, Lazarides K, Perides G, Covic L, Kuliopulos A

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2011 May 17; Vol. 108 (20), pp. 8491-6. Date of Electronic Publication: 2011 May 02.

PAR2 promotes impaired glucose uptake and insulin resistance in NAFLD through GLUT2 and Akt interference.

Autor: Shearer AM; Center for Hemostasis and Thrombosis ResearchTufts Medical CenterBostonMassachusettsUSA.; Tufts University School of Graduate Biomedical Sciences/DMCBTufts University School of MedicineBostonMassachusettsUSA., Wang Y; Center for Hemostasis and Thrombosis ResearchTufts Medical CenterBostonMassachusettsUSA., Fletcher EK; Center for Hemostasis and Thrombosis ResearchTufts Medical CenterBostonMassachusettsUSA., Rana R; Center for Hemostasis and Thrombosis ResearchTufts Medical CenterBostonMassachusettsUSA., Michael ES; Center for Hemostasis and Thrombosis ResearchTufts Medical CenterBostonMassachusettsUSA., Nguyen N; Center for Hemostasis and Thrombosis ResearchTufts Medical CenterBostonMassachusettsUSA., Abdelmalek MF; Division of Gastroenterology and HepatologyDuke University Medical CenterDurhamNorth CarolinaUSA., Covic L; Center for Hemostasis and Thrombosis ResearchTufts Medical CenterBostonMassachusettsUSA.; Tufts University School of Graduate Biomedical Sciences/DMCBTufts University School of MedicineBostonMassachusettsUSA., Kuliopulos A; Center for Hemostasis and Thrombosis ResearchTufts Medical CenterBostonMassachusettsUSA.; Tufts University School of Graduate Biomedical Sciences/DMCBTufts University School of MedicineBostonMassachusettsUSA.

Publikováno v: Hepatology (Baltimore, Md.) [Hepatology] 2022 Dec; Vol. 76 (6), pp. 1778-1793. Date of Electronic Publication: 2022 Jun 11.

THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.

Autor: Alexander, Stephen PH¹ (AUTHOR), Christopoulos, Arthur² (AUTHOR), Davenport, Anthony P³ (AUTHOR), Kelly, Eamonn⁴ (AUTHOR), Mathie, Alistair⁵ (AUTHOR), Peters, John A⁶ (AUTHOR), Veale, Emma L⁷ (AUTHOR), Armstrong, Jane F⁸ (AUTHOR), Faccenda, Elena⁸ (AUTHOR), Harding, Simon D⁸ (AUTHOR), Pawson, Adam J⁸ (AUTHOR), Southan, Christopher⁸ (AUTHOR), Davies, Jamie A⁸ (AUTHOR), Abbracchio, Maria Pia⁹ (AUTHOR), Alexander, Wayne¹⁰ (AUTHOR), Al‐hosaini, Khaled¹¹ (AUTHOR), Bäck, Magnus¹² (AUTHOR), Barnes, Nicholas M.¹³ (AUTHOR), Bathgate, Ross¹⁴ (AUTHOR), Beaulieu, Jean‐Martin¹⁵ (AUTHOR)

Publikováno v: British Journal of Pharmacology. Oct2021 Supplement S1, Vol. 178, pS27-S156. 130p. 1 Color Photograph.