Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sevi, Durdu"'
Autor:
Sebastian Kaluscha, Silvia Domcke, Christiane Wirbelauer, Michael B. Stadler, Sevi Durdu, Lukas Burger, Dirk Schübeler
Publikováno v:
Nature Genetics. 54:1895-1906
Cytosine methylation efficiently silences CpG-rich regulatory regions of genes and repeats in mammalian genomes. To what extent this entails direct inhibition of transcription factor (TF) binding versus indirect inhibition via recruitment of methyl-C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2985aaf6b5aeebfcacdd0b9419894bd7
https://doi.org/10.1038/s41588-022-01241-6
https://doi.org/10.1038/s41588-022-01241-6
Autor:
Luke Isbel, Murat Iskar, Sevi Durdu, Ralph S. Grand, Joscha Weiss, Eric Hietter-Pfeiffer, Zuzanna Kozicka, Alicia K. Michael, Lukas Burger, Nicolas H. Thomä, Dirk Schübeler
The genomic binding sites of the transcription factor (TF) and tumour suppressor p53 are unusually diverse in regards to their chromatin features, including histone modifications, opening the possibility that chromatin provides context-dependence for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faaae4657dd0d41d0867003bacabb2de
https://doi.org/10.1101/2022.08.23.504916
https://doi.org/10.1101/2022.08.23.504916
Autor:
Lukas Burger, Sevi Durdu, Arnaud R Krebs, Sébastien A. Smallwood, Michiel Vermeulen, Marco Pregnolato, Daniel Hess, Luke Isbel, Leslie Hoerner, Cathrin Gräwe, Alicia K. Michael, Ralph S. Grand, Vytautas Iesmantavicius, Nicolas H. Thomä, Dirk Schübeler
Publikováno v:
Nature, 596, 133-137
Nature, 596, pp. 133-137
Nature, 596, pp. 133-137
The majority of gene transcripts generated by RNA polymerase II in mammalian genomes initiate at CpG island (CGI) promoters1,2, yet our understanding of their regulation remains limited. This is in part due to the incomplete information that we have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a435a9b976d10b7b036f5de70743bd26
http://hdl.handle.net/2066/245264
http://hdl.handle.net/2066/245264
Autor:
Ralph S, Grand, Lukas, Burger, Cathrin, Gräwe, Alicia K, Michael, Luke, Isbel, Daniel, Hess, Leslie, Hoerner, Vytautas, Iesmantavicius, Sevi, Durdu, Marco, Pregnolato, Arnaud R, Krebs, Sébastien A, Smallwood, Nicolas, Thomä, Michiel, Vermeulen, Dirk, Schübeler
Publikováno v:
Nature. 596(7870)
The majority of gene transcripts generated by RNA polymerase II in mammalian genomes initiate at CpG island (CGI) promoters
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cfa234815c0ef69421db24fa8c55d126
https://pubmed.ncbi.nlm.nih.gov/34234345
https://pubmed.ncbi.nlm.nih.gov/34234345
Autor:
Naga Venkata, Gayathri Vegesna, Paolo, Ronchi, Sevi, Durdu, Stefan, Terjung, Rainer, Pepperkok
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1563
Laser-mediated dissection methods have been used for many years to micro-irradiate biological samples, but recent technological progress has rendered this technique more precise, powerful, and easy to use. Today pulsed lasers can be operated with dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e4b942012ca5ddeb5b410ef8142ca36d
https://pubmed.ncbi.nlm.nih.gov/28324605
https://pubmed.ncbi.nlm.nih.gov/28324605
Publikováno v:
Methods in Molecular Biology ISBN: 9781493968084
Laser-mediated dissection methods have been used for many years to micro-irradiate biological samples, but recent technological progress has rendered this technique more precise, powerful, and easy to use. Today pulsed lasers can be operated with dif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc945954e4e836481ee7d0d33a7aa0d3
https://doi.org/10.1007/978-1-4939-6810-7_8
https://doi.org/10.1007/978-1-4939-6810-7_8
Autor:
Baris Emre Dayanc, Mesut Tez, Ozlen Konu, Aviram Nissan, Nesrin Turhan, Ismail Gomceli, Ezgi Ozyerli, Musa Akoglu, Sevi Durdu, Erdal Birol Bostanci, Murat Isbilen, Ali O. Gure, Mithat Gonen, Secil Demirkol
Publikováno v:
Journal of Cancer
Background: Prognostic biomarkers for cancer have the power to change the course of disease if they add value beyond known prognostic factors, if they can help shape treatment protocols, and if they are reliable. The aim of this study was to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa741c90e79b8b695934fbc307f89879
https://aperta.ulakbim.gov.tr/record/44607
https://aperta.ulakbim.gov.tr/record/44607
Autor:
Lucy C. Young, Vineetha Vijayakumar, Rupinder Ghatrora, Christina Gewinner, Juan A. Oses-Prieto, Stephen Henderson, Matteo Vietri Rudan, Mark F. Lythgoe, Marta Munoz-Alegre, Sevi Durdu, Sabine Bender, Pablo Rodriguez-Viciana, Nicole Hartig, Amit P. Jathoul, Alma L. Burlingame
Publikováno v:
Molecular Cell. 52(5):679-692
SHOC2 is mutated in Noonan syndrome and plays a key role in the activation of the ERK-MAPK pathway, which is upregulated in the majority of human cancers. SHOC2 functions as a PP1-regulatory protein and as an effector of MRAS. Here we show that SHOC2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b2cc455ebc7bbbe2fa898f66c50f46b
Autor:
Erika Donà, Anton Khmelinskii, Lionel R. Newton, Charlotte Quirin, Sevi Durdu, Joseph Barry, Darren Gilmour, Guillaume Valentin, Michael Knop, Andreas Kunze, Ana Fernandez-Minan, Wolfgang Huber
Publikováno v:
Nature. 503:285-289
It is widely accepted that migrating cells and tissues navigate along pre-patterned chemoattractant gradients; here it is shown that migrating tissues can also determine their own direction by generating local gradients of chemokine activity, via pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a1a34be1f7f2939431e4ff03feb5ed4
https://doi.org/10.1038/nature12635
https://doi.org/10.1038/nature12635
Autor:
Murat Iskar, Andreas Kunze, Peer Bork, Céline Revenu, Sevi Durdu, Yannick Schwab, Darren Gilmour, Nicole L. Schieber
Morphogenesis is the process whereby cell collectives are shaped into differentiated tissues and organs. The self-organizing nature of morphogenesis has been recently demonstrated by studies showing that stem cells in three-dimensional culture can ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3622ed01839adcbd891a611821ddd5d2
https://www.zora.uzh.ch/id/eprint/188395/
https://www.zora.uzh.ch/id/eprint/188395/