Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Severine Le Gac"'
Autor:
Dwi L. Priwitaningrum, Kunal Pednekar, Alexandros V. Gabriël, Aida A. Varela-Moreira, Severine Le Gac, Ivo Vellekoop, Gert Storm, Wim E. Hennink, Jai Prakash
Publikováno v:
Drug delivery and translational research, 13(5), 1470-1483. Springer
Since tumor stroma poses as a barrier to achieve efficacy of nanomedicines, it is essential to evaluate nano-chemotherapeutics in stroma-mimicking 3D models that reliably predict their behavior regarding these hurdles limiting efficacy. In this study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594d553f54fd144b87fd4ab3fd173a40
https://doi.org/10.1007/s13346-023-01310-1
https://doi.org/10.1007/s13346-023-01310-1
Autor:
Pepijn Beekman, Agustin Enciso-Martinez, Sidharam P. Pujari, Leon W. M. M. Terstappen, Han T. Zuilhof, Séverine Le Gac, Cees Otto
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Beekman et al. investigate whether low molecular weight organosilicon compounds leaching out of commonly used biological laboratory materials and household items can interact with molecules found in cellular membranes. The results suggest this is a p
Externí odkaz:
https://doaj.org/article/eb8773121d854b38919c744d26a7d5dd
Autor:
Severine le Gac, Albert van den Berg
The recent explosion in the use of analytical chemistry, particularly in the biological sciences, has led to a need for fast, reliable and highly sensitive tools able to handle small sample sizes. This book illustrates how microfluidics and lab-on-a-
Autor:
Marcia A. M. M. Ferraz, Hoon Suk Rho, Daiane Hemerich, Heiko H. W. Henning, Helena T. A. van Tol, Michael Hölker, Urban Besenfelder, Michal Mokry, Peter L. A. M. Vos, Tom A. E. Stout, Séverine Le Gac, Bart M. Gadella
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
In vitro culture has detrimental effects on transcriptomes and epigenetic programming of zygotes. Here the authors use microfluidic technology to co-culture bovine oviduct epithelial cells with zygotes and show that the transcriptomes and global meth
Externí odkaz:
https://doaj.org/article/b2189c0b6d4a43509e715b245fc4d76a
Autor:
Pepijn Beekman, Agustin Enciso-Martinez, Sidharam P. Pujari, Leon W. M. M. Terstappen, Han Zuilhof, Séverine Le Gac, Cees Otto
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/3afe44a9ceef41289b6139d6cab7ea51
Autor:
Pepijn Beekman, Agustin Enciso-Martinez, Sidharam P. Pujari, Leon W. M. M. Terstappen, Han Zuilhof, Séverine Le Gac, Cees Otto
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/e4fbc9bd88e44ebe9664dfc07dd990ca
Autor:
Valentina Palacio-Castañeda, Lucas Kooijman, Bastien Venzac, Wouter P.R. Verdurmen, Séverine Le Gac
Publikováno v:
Micromachines, Vol 11, Iss 4, p 382 (2020)
Hypoxia switches the metabolism of tumor cells and induces drug resistance. Currently, no therapeutic exists that effectively and specifically targets hypoxic cells in tumors. Development of such therapeutics critically depends on the availability of
Externí odkaz:
https://doaj.org/article/08c35f711b1149f7a222bc8574f3c3bc
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93618 (2014)
While scanning electrochemical microscopy (SECM) is a powerful technique for non-invasive analysis of cells, SECM-based assays remain scarce and have been mainly limited so far to single cells, which is mostly due to the absence of suitable platform
Externí odkaz:
https://doaj.org/article/27a1e9369dbd4975b229bb6b4d68ebc9
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107958 (2014)
The heterogeneity of tumor cells and their alteration during the course of the disease urges the need for real time characterization of individual tumor cells to improve the assessment of treatment options. New generations of therapies are frequently
Externí odkaz:
https://doaj.org/article/bdc8a8de59414ce284482d1940d2205e