Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Severine Kunz"'
Autor:
Alessia Urzi, Ines Lahmann, Lan Vi N. Nguyen, Benjamin R. Rost, Angélica García-Pérez, Noemie Lelievre, Megan E. Merritt-Garza, Han C. Phan, Gary J. Bassell, Wilfried Rossoll, Sebastian Diecke, Severine Kunz, Dietmar Schmitz, Mina Gouti
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The complex neuromuscular network that controls body movements is the target of severe diseases that result in paralysis and death. Here, we report the development of a robust and efficient self-organizing neuromuscular junction (soNMJ) mode
Externí odkaz:
https://doaj.org/article/2a4b36d43f0e4127a2f6076ef4be50b5
Autor:
Adam Myszczyszyn, Oliver Popp, Severine Kunz, Anje Sporbert, Simone Jung, Louis C. Penning, Annika Fendler, Philipp Mertins, Walter Birchmeier
Publikováno v:
PLoS ONE, Vol 19, Iss 3 (2024)
Externí odkaz:
https://doaj.org/article/45df5d4b3c334d8c8c244cadd07071d1
Autor:
Shokoufeh Mahmoodzadeh, Katharina Koch, Cindy Schriever, Jingman Xu, Maria Steinecker, Joachim Leber, Elke Dworatzek, Bettina Purfürst, Severine Kunz, Deborah Recchia, Monica Canepari, Arnd Heuser, Silvia Di Francescantonio, Ingo Morano
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 5, Pp 1249-1265 (2021)
Abstract Background Aging is associated with a progressive reduction in cellular function leading to poor health and loss of physical performance. Mitochondrial dysfunction is one of the hallmarks of aging; hence, interventions targeting mitochondria
Externí odkaz:
https://doaj.org/article/89015aa050f4436080df6d7a85fa6664
Autor:
Annika Fendler, Daniel Bauer, Jonas Busch, Klaus Jung, Annika Wulf-Goldenberg, Severine Kunz, Kun Song, Adam Myszczyszyn, Sefer Elezkurtaj, Bettina Erguen, Simone Jung, Wei Chen, Walter Birchmeier
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Cancer stem cells are thought to be largely resistant to treatment and can be responsible for tumour recurrence. Here, using renal cancer organoids, self-renewing sphere cultures and PDX from patients, the authors show that the proliferation of stem
Externí odkaz:
https://doaj.org/article/e20e23a96a924161a7b8a3b6741f03e9
Autor:
Franziska Schindler, Nicole Praedel, Nancy Neuendorf, Severine Kunz, Sigrid Schnoegl, Michael A. Mason, Bridget A. Taxy, Gillian P. Bates, Ali Khoshnan, Josef Priller, Jan Grimm, Marcel Maier, Annett Boeddrich, Erich E. Wanker
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The deposition of mutant huntingtin (mHTT) protein aggregates in neurons of patients is a pathological hallmark of Huntington’s disease (HD). Previous investigations in cell-free and cell-based disease models showed mHTT exon-1 (mHTTex1) fragments
Externí odkaz:
https://doaj.org/article/39b7832b713b418b99c771d5d66fad70
Autor:
Verena Schoewel, Andreas Marg, Severine Kunz, Tim Overkamp, Romy Siegert Carrazedo, Ute Zacharias, Peter T Daniel, Simone Spuler
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49603 (2012)
Mutations in the dysferlin gene cause the most frequent adult-onset limb girdle muscular dystrophy, LGMD2B. There is no therapy. Dysferlin is a membrane protein comprised of seven, beta-sheet enriched, C2 domains and is involved in Ca(2+)dependent sa
Externí odkaz:
https://doaj.org/article/cb39ce123be842d29078789a4fcd6651
Autor:
Aikaterini Kourpa, Angela Schulz, Eva Mangelsen, Debora Kaiser-Graf, Nils Koppers, Monika Stoll, Michael Rothe, Michael Bader, Bettina Purfürst, Severine Kunz, Thomas Gladytz, Thoralf Niendorf, Sebastian Bachmann, Kerim Mutig, Juliane Bolbrinker, Daniela Panáková, Reinhold Kreutz
Publikováno v:
Hypertension. 80:771-782
Background: Glomerular hyperfiltration (GH) is an important mechanism in the development of albuminuria in hypertension. Upregulation of COX2 (cyclooxygenase 2) and prostaglandin E 2 (PGE 2 ) was linked to podocyte damage in GH. We explored the poten
Autor:
Adam Myszczyszyn, Oliver Popp, Severine Kunz, Anje Sporbert, Simone Jung, Louis C. Penning, Annika Fendler, Philipp Mertins, Walter Birchmeier
Previously, we found that Wnt and Notch signaling govern stem cells of clear cell kidney cancer (ccRCC) in patients. To mimic stem cell responses in the normal kidney in vitro in a marker-unbiased fashion, we have established organoids from total sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb592850a0ab2f4e1a761ead54c2f2ce
https://doi.org/10.1101/2023.02.28.530413
https://doi.org/10.1101/2023.02.28.530413
SummaryFrom swimming to walking and flying, animals have evolved specific locomotor strategies to thrive in different habitats. All types of locomotion depend on integration of motor commands and sensory information to generate precise movements. Cer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6daeb6e75a53ddd7ffdbf5a0e417ff1
https://doi.org/10.1101/2021.12.21.473311
https://doi.org/10.1101/2021.12.21.473311
Autor:
Katrin Gerstmann, Nina Jurčić, Edith Blasco, Severine Kunz, Felipe de Almeida Sassi, Nicolas Wanaverbecq, Niccolò Zampieri
Publikováno v:
Current Biology-CB
Current Biology-CB, 2022, ⟨10.1016/j.cub.2022.04.019⟩
Current Biology-CB, 2022, ⟨10.1016/j.cub.2022.04.019⟩
From swimming to walking and flying, animals have evolved specific locomotor strategies to thrive in different habitats. All types of locomotion depend on the integration of motor commands and sensory information to generate precisely coordinated mov