Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Severine, Sarp"'
Autor:
Roberto Hegg, Hiroji Iwata, G. Kurteva, Michael F. Press, Miguel Izquierdo, Olga Burdaeva, Sergei Tjulandin, Sergio Daniel Simon, Seock-Ah Im, In Hae Park, Sarah Kenny, William J. Gradishar, L. S. Williams, Stephen R. D. Johnston, Severine Sarp
Publikováno v:
J Clin Oncol
PURPOSE Human epidermal growth factor receptor 2 (HER2) targeting plus endocrine therapy (ET) improved clinical benefit in HER2-positive, hormone receptor (HR)–positive metastatic breast cancer (MBC) versus ET alone. Dual HER2 blockade enhances cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8eb3a2d71a16627945c71f5e46b1d76
https://doi.org/10.1200/jco.20.01894
https://doi.org/10.1200/jco.20.01894
Publikováno v:
Clinical Pharmacology and Therapeutics
Clinical Pharmacology & Therapeutics
Clinical Pharmacology & Therapeutics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5efd4a0921b3d00108bc88d12737241a
https://pubmed.ncbi.nlm.nih.gov/33326600
https://pubmed.ncbi.nlm.nih.gov/33326600
Autor:
Serena Di Cosimo, Ryan L Powles, David Redmond, Sherene Loi, Debora Fumagalli, Severine Sarp, José Baselga, Nadia Harbeck, Jens Huober, Martine Piccart-Gebhart, Paolo Nuciforo, Olivier Elemonto, Evandro de Azambuja, Lajos Pusztai, Christos Sotiriou, Christos Hatzis
Publikováno v:
Cancer Research. 78:P2-09
Background: Dual anti-HER2 blockade resulted in increased pathologic complete response rate (pCR) in the 3 arm NeoALTTO trial. High immune gene expression and the absence of PIK3CA pathway mutations are predictive of pCR in all treatment arms but no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9581c9d58c93c686f6dcc0379aa360d4
https://doi.org/10.1158/1538-7445.sabcs17-p2-09-01
https://doi.org/10.1158/1538-7445.sabcs17-p2-09-01
Autor:
L de la Pena, Sherene Loi, David N Brown, J Huober, Ian Bradbury, Françoise Rothé, M Maetens, David Venet, J. Baselga, Debora Fumagalli, M Ignatiadis, E. de Azambuja, Nadia Harbeck, Severine Sarp, Paolo Nuciforo, Roberto Salgado, Lajos Pusztai, M.J. Piccart, Christos Sotiriou
Publikováno v:
Cancer Research. 78:GS1-04
Background In the NeoALTTO trial, the combination of trastuzumab and lapatinib for the neoadjuvant treatment of HER2 positive early breast cancer patients (pts) nearly doubled the rate of pathological complete response (pCR) compared with either anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b83fcdff786a2a5f422fcff9b334b41
https://doi.org/10.1158/1538-7445.sabcs17-gs1-04
https://doi.org/10.1158/1538-7445.sabcs17-gs1-04
Autor:
Pierre Jordaan, Giovanna Muscogiuri, Rosario Pivonello, Michaela Paul, Annamaria Colao, Geoffrey Holder, Anastasia Lesogor, Johannes Eisinger, Severine Sarp
Publikováno v:
Endocrine
Purpose Octreotide (OCT) has been successfully used for treatment of acromegaly and neuroendocrine tumors for more than 30 years. However, long-term safety of OCT has not been documented in placebo-controlled setting. This present analysis pooled saf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9510c7335004c05e6cda5c6fdf58801d
http://europepmc.org/articles/PMC5845597
http://europepmc.org/articles/PMC5845597
Autor:
Christian Jackisch, Christophe Lecocq, Serena Di Cosimo, Frances M. Boyle, José Baselga, Michael Untch, Ian E. Smith, Eileen Holmes, Hans Wildiers, Debora Fumagalli, Martine Piccart-Gebhart, Jens Huober, Hryhoriy Adamchuk, Lorena de la Peña, Richard D. Gelber, Tamas Hickish, John Hackman, Binghe Xu, Evandro de Azambuja, Eva Ciruelos, Juan Carlos Toral Pena, Severine Sarp, Lokanatha Dasappa, István Láng, Christelle Jouannaud
Publikováno v:
European journal of cancer (Oxford, England : 1990). 118
BACKGROUND: Lapatinib (L) plus trastuzumab (T) with weekly paclitaxel significantly increased the pathologic complete response (pCR) rate compared with the anti-human epidermal growth factor receptor 2 (HER2) agent alone plus paclitaxel. The event-fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5cb0ac3ebd56f44f6deb9e3cb6ba2e4
https://pubmed.ncbi.nlm.nih.gov/31377477
https://pubmed.ncbi.nlm.nih.gov/31377477
Autor:
José Baselga, Ryan L Powles, Debora Fumagalli, Christos Hatzis, Olivier Elemento, Jens Huober, Nadia Harbeck, Martine Piccart-Gebhart, Evandro de Azambuja, Lajos Pusztai, Serena Di Cosimo, Sherene Loi, Christos Sotiriou, David Redmond, Severine Sarp, Paolo Nuciforo
IMPORTANCE: Dual anti-HER2 blockade increased the rate of pathologic complete response (pCR) in the Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation (NeoALTTO) trial, and high immune gene expression was associated with pCR in all treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::665b4d874fd4f8ed75220684237d42ef
https://europepmc.org/articles/PMC6224305/
https://europepmc.org/articles/PMC6224305/
Autor:
Masakazu Toi, Julie Gralow, Maccon M. Keane, Alvaro Moreno-Aspitia, Antonio C. Wolff, Debora Fumagalli, Ian Bradbury, Severine Sarp, Judith R. Kroep, Martin Andersson, Evandro de Azambuja, Hatem A. Azim, Lyndsay Harris, Martine Piccart-Gebhart, Amir Sonnenblick, Serena Di Cosimo, Dominique Agbor-Tarh, Tanja Cufer, Pamela Salman, Sergio Daniel Simon
Publikováno v:
Journal of Clinical Oncology, 35(13), 1421
Purpose Previous studies have suggested an association between metformin use and improved outcome in patients with diabetes and breast cancer. In the current study, we aimed to explore this association in human epidermal growth factor receptor 2 (HER
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::774c6bcdcea5f8ecfef22f044dd4d880
http://hdl.handle.net/10379/13984
http://hdl.handle.net/10379/13984
Autor:
Christiane Michel, David J. Lewis, Philippe Close, Severine Sarp, Conny Berlin, Michael Petrin, Dionigi D. Maladorno, Carles Blanch
Publikováno v:
Pharmacoepidemiology and Drug Safety. 21:622-630
Purpose The detection of safety signals with medicines is an essential activity to protect public health. Despite widespread acceptance, it is unclear whether recently applied statistical algorithms provide enhanced performance characteristics when c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6d77c9277e06d4fb0fe8a25c9825bf
https://doi.org/10.1002/pds.2247
https://doi.org/10.1002/pds.2247