Výsledky vyhledávání - "Severina Moreira"

Molecular and Genotypic Characterization of Human Thyroid Follicular Cell Carcinoma–Derived Cell Lines

Autor: Cíntia Alves, Ana Rocha, Vítor Trovisco, Valdemar Máximo, Manuel Sobrinho-Simões, Isabel Pereira-Castro, Sérgia Velho, Ana M. Meireles, Tiago Botelho, Tália Feijão, Luis Cirnes, Ana Preto, Ricardo Marques, Severina Moreira, Ana Paula Rebocho, Paula Soares

Publikováno v: Thyroid. 17:707-715

Our aim was to characterize the molecular and genotypic profile of eight thyroid carcinoma-derived cell lines-TPC1, FB2, B-CPAP, K1, XTC-1, C643, 8505C, and Hth74-in order to use them as in vitro models of thyroid carcinogenesis.We evaluated the expr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7121fa0122380d6aa448284e0d50eea1
https://doi.org/10.1089/thy.2007.0097

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Type and prevalence of BRAF mutations are closely associated with papillary thyroid carcinoma histotype and patients’ age but not with tumour aggressiveness

Autor: Ana Preto, Patrícia Castro, Paula Soares, Valdemar Máximo, Manuel Sobrinho-Simões, Severina Moreira, Ana M. Meireles, José Cameselle-Teijeiro, Vítor Trovisco, Tiago Botelho, Jorge Lima, Alexander Abrosimov, Inês Vieira de Castro, J.F Magalhaes

Publikováno v: Virchows Archiv. 446:589-595

A high prevalence of the BRAF(V600E) somatic mutation was recently reported in several series of papillary thyroid carcinomas (PTC). This mutation appears to be particularly prevalent in PTC with a predominantly papillary architecture. Another BRAF m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de1fe3c1c9025f05214357ea09f90168
https://doi.org/10.1007/s00428-005-1236-0

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An evaluation of the effectiveness of a multi-modal intervention in frail and pre-frail older people with type 2 diabetes - the MID-Frail study: study protocol for a randomised controlled trial

Autor: Leocadio, Rodríguez-Mañas, Antony J, Bayer, Mark, Kelly, Andrej, Zeyfang, Mikel, Izquierdo, Olga, Laosa, Timothy C, Hardman, Alan J, Sinclair, Severina, Moreira, Justin, Cook

Publikováno v: Academica-e. Repositorio Institucional de la Universidad Pública de Navarra
instname
Trials
Academica-e: Repositorio Institucional de la Universidad Pública de Navarra
Universidad Pública de Navarra

Background Diabetes, a highly prevalent, chronic disease, is associated with increasing frailty and functional decline in older people, with concomitant personal, social, and public health implications. We describe the rationale and methods of the mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c37fd871ff782e54778597b89be44802
https://doi.org/10.1186/1745-6215-15-34

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GRIM-19 function in cancer development

Autor: Paula Soares, Valdemar Máximo, Marcelo Correia, Severina Moreira

Publikováno v: Mitochondrion. 11(5)

Cancer development involves multiple genetic changes, which can occur in tumor suppressor genes and lead to loss of function in a recessive manner. Recent findings have identified a novel tumor suppressor gene named GRIM-19. Similar to what has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfd14802f1b1919e5532da0d92d18223
https://pubmed.ncbi.nlm.nih.gov/21664299

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Clasp-mediated microtubule bundling regulates persistent motility and contact repulsion in Drosophila macrophages in vivo

Autor: Chieh-Yin Huang, Paul Martin, Martin J. Milner, Thomas H. Millard, Ola Sabet, Severina Moreira, Graham Dunn, Iwan Robert Evans, Brian Stramer, Will Wood

Publikováno v: The Journal of Cell Biology

A microtubule arm regulates cell–cell repulsion, pointing hemocytes in opposite directions when they contact each other in Drosophila embryos.
Drosophila melanogaster macrophages are highly migratory cells that lend themselves beautifully to h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f59a198bceab3de999519f6ee9c4daf
http://jcb.rupress.org/content/189/4/681.abstract

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Prioritization of competing damage and developmental signals by migrating macrophages in the Drosophila embryo

Autor: Brian Stramer, Will J Wood, Paul Martin, Iwan Robert Evans, Severina Moreira

Publikováno v: Current biology : CB. 20(5)

SummaryThe function of immune cells is critically dependent on their capacity to respond to a complex series of navigational cues that enable them to home to various organ sites in the body or to respond to inflammatory cues such as those released at

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad7666e39f0f5f8f59bda13b7af6f1c6
https://pubmed.ncbi.nlm.nih.gov/20188558

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