Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Severin T. Schneebeli"'
Autor:
Elizabeth M. Corteselli, Mona Sharafi, Robert Hondal, Maximilian MacPherson, Sheryl White, Ying-Wai Lam, Clarissa Gold, Allison M. Manuel, Albert van der Vliet, Severin T. Schneebeli, Vikas Anathy, Jianing Li, Yvonne M. W. Janssen-Heininger
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Protein-S-glutathionylation is a post-translational modification involving the conjugation of glutathione to protein thiols, which can modulate the activity and structure of key cellular proteins. Glutaredoxins (GLRX) are oxidoreductases tha
Externí odkaz:
https://doaj.org/article/b5c9d223376f4a1cb9e9e02ac6e0d59e
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Structure-based drug design targeting the SARS-CoV-2 virus has been greatly facilitated by available virus-related protein structures. However, there is an urgent need for effective, safe small-molecule drugs to control the spread of the vir
Externí odkaz:
https://doaj.org/article/2821bc4e151f414ba4c52588287f8f20
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The lack of biologically relevant protein structures can hinder rational design of small molecules to target G protein-coupled receptors (GPCRs). While ensemble docking using multiple models of the protein target is a promising technique for structur
Externí odkaz:
https://doaj.org/article/cf0dcf8afb874bad88fbd8103b278822
Publikováno v:
Organic Materials, Vol 03, Iss 02, Pp 337-345 (2021)
Abstract We synthesized some of the longest unimolecular oligo(p-phenylene ethynylenes) (OPEs), which are fully substituted with electron-withdrawing ester groups. An iterative convergent/divergent (a.k.a. iterative exponential growth – IEG) strate
Externí odkaz:
https://doaj.org/article/65e85c25d7bc41329f41f1553739d29e
Autor:
Tyler J. Jaynes, Mona Sharafi, Joseph P. Campbell, Jessica Bocanegra, Kyle T. McKay, Kassondra Little, Reilly Osadchey Brown, Danielle L. Gray, Toby J. Woods, Jianing Li, Severin T. Schneebeli
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
This work presents the first transition metal-free synthesis of oxygen-linked aromatic polymers by integrating iterative exponential polymer growth (IEG) with nucleophilic aromatic substitution (SNAr) reactions. Our approach applies methyl sulfones a
Externí odkaz:
https://doaj.org/article/54d5f6dd58f64d3dbc7852b28719d395
Autor:
Kyle E. Murphy, Jessica L. Bocanegra, Xiaoxi Liu, H.-Y. Katharine Chau, Patrick C. Lee, Jianing Li, Severin T. Schneebeli
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Regioselectivity during electrophilic aromatic substitution is typically controlled by substituents on the aryl group. Here the authors report an electrophilic aromatic substitution reaction, wherein remote chiral ester groups direct the electrophile
Externí odkaz:
https://doaj.org/article/cb1c33951f5949f3945f2056f03c8208
Publikováno v:
CHIMIA, Vol 68, Iss 5 (2014)
Since the concept of second-sphere coordination of transition metal complexes was introduced by Alfred Werner in 1913, the investigation of the phenomenon has emerged as a major thrust area — a significant part of which is based on the use of trans
Externí odkaz:
https://doaj.org/article/0700daf34c3a41ea939db616026473df
Autor:
Jacob M Remington, Kyle T McKay, Noah B Beckage, Jonathon B Ferrell, Severin T. Schneebeli, Jianing Li
Publikováno v:
Journal of Computer-Aided Molecular Design. 37:147-156
Autor:
Arash Ghalehgolabbehbahani, Olav Vestrheim, Margaret Skinner, Jianing Li, Severin T. Schneebeli
Publikováno v:
ACS Food Science & Technology. 2:315-320
Publikováno v:
Journal of Chemical Education. 99:639-645