Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Severin SE"'
Publikováno v:
Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry. 9:312-324
The review summarizes literature data on the antitumor activity of niclosamide and its molecular mechanisms. Earlier niclosamide was used for treatment of intestinal parasitic infections. Recent screening of various drugs and chemical compounds, aime
Autor:
Julian Maier, Thomas Lambert, Thomas Senoner, Stephan Dobner, Uta Caroline Hoppe, Alexander Fellner, Bernhard Erich Pfeifer, Gudrun Maria Feuchtner, Guy Friedrich, Severin Semsroth, Nikolaos Bonaros, Johannes Holfeld, Silvana Müller, Markus Reinthaler, Clemens Steinwender, Fabian Barbieri
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionPrevious analyses have reported the outcomes of transcatheter aortic valve replacement (TAVR) for patients with low-flow, low-gradient (LFLG) aortic stenosis (AS), without stratifying according to the route of access. Differences in morta
Externí odkaz:
https://doaj.org/article/79fae0e7d147425fb583525a44381c45
Publikováno v:
Biochemistry (Moscow). 72:235-246
Endogenous inhibitors of angiogenesis are proved to be a major factor preventing the emergence of clinically manifested stages of human cancer. The protein endostatin, a 20-kD proteolytic fragment of type XVIII collagen, is one of the most active nat
Autor:
L. A. Menshikova, Yarushok Ta, T. N. Komarov, E. G. Dubovik, Dubovik Ns, Yu. V. Medvedev, Kuznetsova Ig, Severin Se, Shohin Ie
Publikováno v:
Vestnik Rossiiskoi akademii meditsinskikh nauk. (3)
Background : One way to increase drug efficacy is to provide a drug delivery transport system to the target organ. A widely used method is to incorporate the drug in a biodegradable polymer composition with forming nanosized drug’s transport forms.
Publikováno v:
Biochemistry (Moscow). 68:286-300
The maintenance of growth of malignant tumors is closely related with the development of the vascular network supplying the tumor with blood. The vascularization of tumor tissue is similar to physiological angiogenesis, but in tumors it has some spec
Publikováno v:
Biochemistry (Moscow). 68:497-513
Formation of the blood supply system is a critical step in malignant transformation of neoplasms which results in the penetration of tumor cells into neighboring tissues and metastatic growth. Significant progress in the elucidation of mechanisms und
Autor:
B Turowski, Z.S. Smirnova, F.E Zanella, I. N. Skidan, Alexander S. Khalansky, A.I. Bobruskin, Severin Se, Svetlana Gelperina, Joerg Kreuter
Publikováno v:
Toxicology Letters. 126:131-141
Polysorbate 80-coated poly(butyl cyanoacrylate) nanoparticles (NP) were shown to enable the transport of a number of drugs including the anti-tumour antibiotic doxorubicin (DOX) across the blood-brain barrier (BBB) to the brain after intravenous admi
Publikováno v:
Journal of Drug Targeting. 10:567-571
The epidermal growth factor (EGF) receptor is expressed at high levels on many types of tumor cells, such as squamous carcinoma, breast cancer and endothelial cells. We studied targeted delivery of the anticancer drug doxorubicin (DOX) using EGF and
Autor:
V. A. Makarov, G. A. Posypanova, A. V. Khomyakova, E. Yu. Moskaleva, Severin Se, N. V. Gukasova, A. V. Rodina, I. G. Kondrasheva, O. N. Popova
Publikováno v:
Biochemistry. Biokhimiia. 73(7)
Recombinant human MIS (rhMIS) produced in transfected Chinese hamster ovary cells has been purified by immunoaffinity chromatography. In the absence of reducing agents, 140 kD homodimer and several oligomers with molecular masses from 280 to 1000 kD
Autor:
Alexander I. Sotnichenko, R. V. Petrov, Eugene S. Severin, G.A. Posypanova, Michael I. Grigor'ev, Severin Se, Natalya Borisovna Feldman
Publikováno v:
FEBS letters. 450(1-2)
The conditions for the formation of a non-covalent complex between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and the human transport fetal protein, α-fetoprotein (AFP), have been studied. TCDD has been shown to form a stable complex with AFP in a 2