Zobrazeno 1 - 10
of 369
pro vyhledávání: '"Severin ES"'
Autor:
Olga A. Sharapova, Daniela K. Laurinavichyute, N. V. Pozdnyakova, Maria S. Yurkova, A. N. Fedorov, G.A. Posypanova, S. M. Andronova, S. E. Severin, Severin Es
Publikováno v:
Russian Journal of Bioorganic Chemistry. 36:696-703
Alpha-fetoprotein (AFP) is the major human oncofetal protein. The receptor of AFP is expressed by cells of various tumors and is not produced by normal cells of the adult body. In an AFP molecule, the site of binding to its receptor is localized in t
Autor:
Olga A. Sharapova, Maria S. Yurkova, Natalia V. Pozdnykova, G.A. Posypanova, S. E. Severin, Severin Es, Daniela K. Laurinavichyute, A. N. Fedorov
Publikováno v:
Protein Expression and Purification. 73:31-35
Human alpha-fetoprotein (hAFP) is an oncofetal protein which is a common cancer marker. Conjugates of native hAFP with different cytostatic agents inhibit growth of cancer cells in vivo and in vitro. The hAFP interacts with its receptor (AFPR) on the
Autor:
Galina A Posypanova, Ludmila V Savvateeva, S. E. Severin, Neonila V. Gorokhovets, Natalya N Kireeva, Vladimir A Makarov, Severin Es
Publikováno v:
Journal of Drug Targeting. 16:321-328
The specific receptor of alpha-fetoprotein (AFP) is a universal tumor marker, being expressed on the surface of many tumor cells, but not in normal human tissues. AFP enters the cell by receptor-mediated endocytosis; its receptor-binding site is hypo
Autor:
I. P. Beletskii, Severin Es, S. E. Severin, T. Z. Vezirkhanova, E. Yu. Moskaleva, V. V. Strelnikov, A. V. Rodina, L. V. Sladkova, M. A. Ivanov, N. N. Belushkina, O. V. Prusakova, V. V. Obuchova
Publikováno v:
Molecular Biology. 39:35-41
Experiments on the transfection of cultured SKOV3 tumor cells of human ovarian adenocarcinoma and HeLa cells of human cervical carcinoma with gene Bax have demonstrated that SKOV3 cells are highly sensitive to the protein product of this gene, wherea
Autor:
Anastasiya V. Bereznikova, Vladimir A. Makarov, Mariya V. Savvateeva, G.A. Posypanova, Severin Es
Publikováno v:
Journal of drug targeting. 21(5)
The alpha-fetoprotein (AFP) binding protein, a putative AFP receptor, is a tumour marker that is present on the surfaces of malignant cells. AFP enters cells through receptor-mediated endocytosis. The recombinant C-terminal fragment of AFP (AFP-3BC,
Publikováno v:
Journal of Biomedicine and Biotechnology, Vol 2012 (2012)
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology
A new chimeric geneApE1encoding the receptor-binding domain of the humanalpha-fetoprotein fused to a sequence of 22 glutamic acid residues was constructed. A new bacterial producer strainE. coliSHExT7 ApE1 was selected for ApE1 production in a solubl
Autor:
Olga A. Sharapova, S. E. Severin, Severin Es, Svetlana M. Andronova, Daniela K. Laurinavichyute, A. N. Fedorov, Maria S. Yurkova
Publikováno v:
Journal of chromatography. A. 1218(31)
The efficient refolding of recombinant proteins produced in the form of inclusion bodies (IBs) in Escherichia coli still is a complicated experimental problem especially for large hydrophobic highly disulfide-bonded proteins. The aim of this work was
Autor:
Piotr Garnuszek, Michał Maurin, G J Mizejewski, B D Cohen, Marek Mirowski, Severin Es, B J Poiesz, G.A. Posypanova, S. E. Severin, V A Makarov
Publikováno v:
Journal of drug targeting. 18(8)
The alpha-fetoprotein derived growth inhibitory peptide (GIP) is a 34-amino acid peptide composed of three biologically active subfragments. GIP-34 and its three constituent segments have been synthesized, purified, and studied for biological activit
Autor:
Severin Es
Publikováno v:
Russian Journal of Bioorganic Chemistry. 26:700-701
Francis Crick rather clearly predicted in his report that the major advances in molecular biology will occur in the studies on the mechanism of muscle contraction, problems on immunity, action of hormones, formation of memory, etc. It should be empha
Autor:
E.E. Zotova, Severin Se, I.I. Shmyrev, M.A. Choladze, O. N. Popova, G.A. Posypanova, I. A. Tubasheva, Severin Es, A.D. Kondratyev
Publikováno v:
FEBS letters. 264(1)
The effect of nerve growth factor (NGF) on the activity and intracellular localization of protein kinase C (PKC) in pheochromocytoma PC12 cells was studied. By using immunoblotting, immunofluorescence method and phorbol ester binding, NGF was found t