Výsledky vyhledávání - "Seventer, G. A."

The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells

Autor: Seventer, G. A., Yoji Shimizu, Horgan, K. J., Shaw, S.

Publikováno v: Scopus-Elsevier

Functional studies demonstrate that T cell activation often requires not only occupancy of the TCR but costimulatory interactions of other molecules, which remain largely undefined. We have tested the hypothesis that LFA-1 interaction with its ligand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdc91cbf26d42f4b17731dab647ee3d0
https://doi.org/10.4049/jimmunol.144.12.4579

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Generation of alloreactive cytolytic T lymphocytes by immobilized anti-CD3 monoclonal antibodies. Analysis of requirements for human cytolytic T-lymphocyte differentiation

Autor: Jong, R., Brouwer, M., Rebel, V. I., Seventer, G. A., Miedema, F., Rene van Lier

Publikováno v: Immunology, 70(3), 357-364. Wiley-Blackwell
Scopus-Elsevier

Requirements for the induction of human cytolytic T-lymphocyte (CTL) activity were studied in a monocyte-free T-cell activation system that uses immobilized anti-CD3 monoclonal antibodies (mAb) as a stimulus. Alloreactive CTL with specificity for HLA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::15f7682555ce95b7a14b91af833c8100
https://pure.amc.nl/en/publications/generation-of-alloreactive-cytolytic-t-lymphocytes-by-immobilized-anticd3-monoclonal-antibodies-analysis-of-requirements-for-human-cytolytic-tlymphocyte-differentiation(43bc86e9-9737-4377-a0b5-7032967e9b33).html

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Interferon- β Mediates Opposing Effects on Interferon- γ-dependent Interleukin-12 p70 Secretion by Human Monocyte-Derived Dendritic Cells.

Autor: Nagai, T., Devergne, O., van Seventer, G. A., van Seventer, J. M.

Publikováno v: Scandinavian Journal of Immunology; Feb2007, Vol. 65 Issue 2, p107-117, 11p, 6 Diagrams

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Treatment of rheumatoid arthritis with baricitinib or upadacitinib is associated with reduced scaffold protein NEDD9 levels in CD4+ T cells.

Autor: Golumba‐Nagy, Viktoria¹ (AUTHOR), Yan, Shuaifeng¹ (AUTHOR), Steinbach‐Knödgen, Eva¹ (AUTHOR), Thiele, Jan¹ (AUTHOR), Esser, Ruth L.¹ (AUTHOR), Haak, Thomas H.^1,2 (AUTHOR), Nikiforov, Anastasia^1,3 (AUTHOR), Meyer, Anja¹ (AUTHOR), Seeger‐Nukpezah, Tamina^1,3 (AUTHOR), Kofler, David M.^1,3 (AUTHOR) david.kofler@uk‐koeln.de

Publikováno v: Physiological Reports. Oct2023, Vol. 11 Issue 19, p1-8. 8p.

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Generation of alloreactive cytolytic T lymphocytes by immobilized anti-CD3 monoclonal antibodies. Analysis of requirements for human cytolytic T-lymphocyte differentiation.

Autor: De Jong, R., Brouwer, M., Rebel, V. I., Van Seventer, G. A., Miedema, F., Van Lier, R. A. W.

Publikováno v: Immunology; Jul90, Vol. 70 Issue 3, p357-364, 8p

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Differential recognition by human cytotoxic T cell clones of human M1 fibroblasts transfected with an HLA-B7 gene (JY150) suggests the existence of two different HLA-B7 alleles in the cell line JY (HLA-A2,2;B7,7;Cw-,-;DR4,w6)

Autor: van Seventer, G. A., Spits, H., Yssel, H., Melief, C. J., Ivanyi, P.

Publikováno v: Journal of immunology (Baltimore, Md., 141(2), 417-422. American Association of Immunologists

We have used a panel of human HLA-B7-specific CTL clones to identify an HLA-B7 gene (JY150) transfected into human M1 fibroblasts (M1/B7). Only a subset of the CTL clones recognized the M1/B7 cells, whereas all CTL clones recognized the donor of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be0bae01b9944b8ca05eaa76a507a25
https://doi.org/10.4049/jimmunol.141.2.417

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Mechanism of inhibition and induction of cytolytic activity in cytotoxic T lymphocytes by CD3 monoclonal antibodies

Autor: Seventer, G. A., Kuijpers, K. C., Rene van Lier, Groot, E. R., Aarden, L. A., Melief, C. J. M.

Publikováno v: Journal of immunology (Baltimore, Md., 139(8), 2545-2550. American Association of Immunologists
Scopus-Elsevier

The objective of this study was to elucidate the mechanism responsible for inhibition as well as induction of cytolytic activity in cytotoxic T lymphocytes (CTL) by cluster-defined 3 (T3) (CD3) monoclonal antibodies (mAb). A series of isotype heavy c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c680168317b8ecfea2fdb1550421a50
https://doi.org/10.4049/jimmunol.139.8.2545

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