Výsledky vyhledávání - "Sevdalina Yurukova"

CaMKII-mediated increased lusitropic responses to β-adrenoreceptor stimulation in ANP-receptor deficient mice

Autor: Otto-Erich Brodde, Michaela Kuhn, Nataliya Dybkova, Ana Kilic, Kirsten Leineweber, Sevdalina Yurukova, Katharina Völker, Lars S. Maier

Publikováno v: Cardiovascular Research. 73:678-688

Mice with genetic disruption of the guanylyl cyclase-A (GC-A) receptor for atrial natriuretic peptide (ANP), have chronic arterial hypertension and marked cardiac hypertrophy. Intriguingly, despite pronounced remodeling, cardiac contractile functions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9f9bad6e763b9e0c5ecf911c3ce72f
https://doi.org/10.1016/j.cardiores.2006.10.003

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Increased effects of C-type natriuretic peptide on contractility and calcium regulation in murine hearts overexpressing cyclic GMP-dependent protein kinase I

Autor: Kai C. Wollert, Suzanne M. Lohmann, Frank Begrow, Ulrich Walter, Sevdalina Yurukova, Stepan Gambaryan, Ana Kilic, Michaela Kuhn, Beate Fiedler

Publikováno v: British Journal of Pharmacology. 140:1227-1236

C-type natriuretic peptide (CNP) and its receptor guanylyl cyclase (GC-B) are expressed in the heart and modulate cardiac contractility in a cGMP-dependent manner. Since the distal cellular signalling pathways remain unclear, we evaluated the peptide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5f9c0a5a89ca30351275e84ebe469f80
https://doi.org/10.1038/sj.bjp.0705567

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Calcium‐calmoduline kinase II plays a important role in cardiac hypertrophy in ANP receptor deficient mice

Autor: Larissa Fabritz, Michaela Kuhn, Ana Kilic, Danuta Mitko, Sevdalina Yurukova

Publikováno v: The FASEB Journal. 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d1cd0aa88c43b4674d90bb2623ddd9a1
https://doi.org/10.1096/fasebj.20.4.a311-a

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Increased tissue expression and activity of cGMP-dependent protein kinase I in ANP-receptor (GC-A) – deficient mice

Autor: Ulrich Walter, Sevdalina Yurukova, Melanie Voss, Wolfgang R. Dostmann, Stepan Gambaryan, Thomas Renné, Ana Kilic, Michaela Kuhn

Publikováno v: BMC Pharmacology. 5

Background In many tissues, a key mediator of cGMP signaling is cGMP-dependent protein kinase I (PKG I). In vitro and in vivo studies have shown that cGMP may not only regulate the kinase activity but also the expression levels of PKG I. Thus, chroni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bfc7803be4f9d84e2dbb91d2265c2a8
https://doi.org/10.1186/1471-2210-5-s1-p25

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