Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Seungyeon Yang"'
Autor:
Sunsook Hwang, Seungyeon Yang, Kyungsoo Park, Byungjoo Kim, Minjoong Kim, Seungmin Shin, Ahyoung Yoo, Jiyun Ahn, Juneil Jang, Yeong Shin Yim, Rho H. Seong, Seung Min Jeong
Publikováno v:
Advanced Science, Vol 11, Iss 10, Pp n/a-n/a (2024)
Abstract The DNA damage response is essential for preserving genome integrity and eliminating damaged cells. Although cellular metabolism plays a central role in cell fate decision between proliferation, survival, or death, the metabolic response to
Externí odkaz:
https://doaj.org/article/b182c5a25c4547a98f407647ac2477bf
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract DNA repair is a tightly coordinated stress response to DNA damage, which is critical for preserving genome integrity. Accruing evidence suggests that metabolic pathways have been correlated with cellular response to DNA damage. Here, we show
Externí odkaz:
https://doaj.org/article/5a76d857609343f1896a02efb887c8d1
Autor:
Sunsook Hwang, Seungyeon Yang, Minjoong Kim, Youlim Hong, Byungjoo Kim, Eun Kyung Lee, Seung Min Jeong
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract The DNA damage response is essential for sustaining genomic stability and preventing tumorigenesis. However, the fundamental question about the cellular metabolic response to DNA damage remains largely unknown, impeding the development of me
Externí odkaz:
https://doaj.org/article/e7fb5d356d7c4a37852134b32a92bf7b
Publikováno v:
International Journal of Human Movement Science. 16:29-45
Autor:
Byungjoo Kim, Jihye Gwak, Minjoong Kim, Seungyeon Yang, Sunsook Hwang, Seungmin Shin, Ji Hye Kim, Jaekyoung Son, Seung Min Jeong
Publikováno v:
Cancer Gene Therapy.
Publikováno v:
Oncogene. 38(24)
Cancer cells exhibit metabolic dependence on mitochondrial glutamine metabolism that provides them with the substrates required for rapid proliferation. Despite the extensive efforts to target this glutamine addiction for therapeutic purposes, the ad
Publikováno v:
Biochemical and biophysical research communications. 501(3)
Contact inhibition (CI) is an important tumor-suppressive mechanism that arrests cell cycle when cells reach high density. Indeed, CI is aberrantly absent in cancer cells and the dysregulation of this can contribute to tumorigenesis. Previously, it h
Publikováno v:
Cell Death and Disease, Vol 9, Iss 2, Pp 1-10 (2018)
Cell Death & Disease
Cell Death & Disease
Cellular senescence, which leads to a cell cycle arrest of damaged or dysfunctional cells, is an important mechanism to restrain the malignant progression of cancer cells. Because metabolic changes underlie many cell-fate decisions, it has been sugge
Publikováno v:
SCIENTIFIC REPORTS(6)
Scientific Reports
Scientific Reports
Cancer cells use precursors derived from tricarboxylic acid (TCA) cycle to support their unlimited growth. However, continuous export of TCA cycle intermediates results in the defect of mitochondrial integrity. Mitochondria glutamine metabolism plays