Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Seungyeon Ryu"'
Autor:
So-Hyun Yoon, Sangeun Lee, Hoe Suk Kim, Junhyuk Song, Moonjou Baek, Seungyeon Ryu, Han-Byoel Lee, Hyeong-Gon Moon, Dong-Young Noh, Sangyong Jon, Wonshik Han
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background NAD(P)-dependent steroid dehydrogenase-like protein (NSDHL), which is involved in breast tumor growth and metastasis, has been implicated in the maintenance of cancer stem cells. However, its role in regulating breast cancer stem-
Externí odkaz:
https://doaj.org/article/7db479f810e941bcb9add8110729df41
Autor:
Hyosun Tak, Seongho Cha, Youlim Hong, Myeongwoo Jung, Seungyeon Ryu, Sukyoung Han, Seung Min Jeong, Wook Kim, Eun Kyung Lee
Publikováno v:
Cell Death and Disease, Vol 15, Iss 6, Pp 1-11 (2024)
Abstract Senescent cells exhibit a diverse spectrum of changes in their morphology, proliferative capacity, senescence-associated secretory phenotype (SASP) production, and mitochondrial homeostasis. These cells often manifest with elongated mitochon
Externí odkaz:
https://doaj.org/article/b2d855c1574c45fbb54d081ddc88c1b1
Autor:
Seongho Cha, Chongtae Kim, Myeongwoo Jung, Seungyeon Ryu, Sukyoung Han, Wook Kim, Eun Kyung Lee
Publikováno v:
Genes and Diseases, Vol 11, Iss 4, Pp 101144- (2024)
Externí odkaz:
https://doaj.org/article/40503a1c26e14290a68383b07561f023
Autor:
Seungyeon Ryu, So-Hyun Yoon, Junhyuk Song, Yoonjung Choi, Sangeun Lee, Moonjou Baek, Han-Byoel Lee, Sook Young Jeon, Sangyong Jon, Daeyoup Lee, Hoe Suk Kim, Wonshik Han
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Heterogeneous tumor cells are thought to be a significant factor in the failure of endocrine therapy in estrogen receptor-positive (ER+) cancers. Culturing patient-derived breast cancer cells (PDBCCs) provides an invaluable tool i
Externí odkaz:
https://doaj.org/article/78820f2c6a8248cda9346c4ac8a42ccb
Autor:
Myeongwoo Jung, Seungyeon Ryu, Chongtae Kim, Seongho Cha, Hoin Kang, Eunbyul Ji, Youlim Hong, Youngjoon Lee, Sukyoung Han, Seung Min Jeong, Wook Kim, Eun Kyung Lee
Publikováno v:
Cell Death and Disease, Vol 13, Iss 12, Pp 1-11 (2022)
Abstract RNA binding protein HuD plays essential roles in gene expression by regulating RNA metabolism, and its dysregulation is involved in the pathogenesis of several diseases, including tumors, neurodegenerative diseases, and diabetes. Here, we ex
Externí odkaz:
https://doaj.org/article/f06828dbca184b6cae3577f2eea273e9
Autor:
Seungyeon Ryu, Myeongwoo Jung, Chongtae Kim, Hoin Kang, Sukyoung Han, Seongho Cha, Seung Min Jeong, Eun Kyung Lee
Publikováno v:
Cell Death and Disease, Vol 13, Iss 4, Pp 1-10 (2022)
Abstract HuD, an RNA binding protein, plays a role in the regulation of gene expression in certain types of cells, including neuronal cells and pancreatic β-cells, via RNA metabolism. Its aberrant expression is associated with the pathogenesis of se
Externí odkaz:
https://doaj.org/article/968274a36c86499d9eec0ca5396cde41
Autor:
Moonjou Baek, Hoe Suk Kim, So-Hyun Yoon, Seungyeon Ryu, Sangeun Lee, Kyoungsook Park, Han-Byoel Lee, Wonshik Han
Publikováno v:
Cancer Research. 83:P5-13
Background: We had identified somatic mutations of the NAD(P) Dependent Steroid Dehydrogenase-Like (NSDHL) gene from breast tumors of patients with distant metastasis using whole-exome sequencing. This study aimed to investigate the function of NSDHL
Autor:
Sangeun Lee, Hoe Suk Kim, So-Hyun Yoon, Seungyeon Ryu, Moonjou Baek, A Young Park, Han-Byoel Lee, Wonshik Han
Publikováno v:
Cancer Research. 83:P2-26
Background: Statins were suggested for repurposed drugs, having multifaceted effects which include anti-tumor activities by modulating the immune response. Here, we aimed to demonstrate the effect of statins on programmed death-ligand 1 (PD-L1) expre
Autor:
So-Hyun Yoon, Hoe Suk Kim, Junhyuk Song, Sunkyu Kwon, Seungyeon Ryu, Moonjou Baek, Sangeun Lee, Han-Byoel Lee, Hyeong-Gon Moon, Dong-Young Noh, Sangyong Jon, Wonshik Han
Publikováno v:
Cancer Research. 82:P5-12
Background: Cholesterol biosynthesis pathway is commonly elevated or dysregulated in cancer cells and high cholesterol levels are associated with cancer progression. NAD(P)-dependent steroid dehydrogenase-like (NSDHL), an enzyme involved in cholester
Autor:
Seungyeon RYU, Hoe Suk Kim, So-Hyun Yoon, Sangeun Lee, Junhyuk Song, Moonjou Baek, Han-Byoel Lee, Sangyong Jon, Wonshik Han
Publikováno v:
Cancer Research. 82:P1-05
Purpose: Immunophenotyping is a useful tool for diagnostic and therapeutic assessment of heterogenous breast cancer cells that depend on external factors and growth conditions. The objective of this study was to characterize the phenotype of patient-