Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Seungwha Paik"'
Autor:
Asmita Sapkota, Eun-Jin Park, Young Jae Kim, Jong Beom Heo, Thanh Quang Nguyen, Bo Eun Heo, Jin Kyung Kim, Sang-Hee Lee, Soo In Kim, Yoon-Jung Choi, Taylor Roh, Sang Min Jeon, Marnpyung Jang, Hae Joon Heo, Jake Whang, Seungwha Paik, Jae-Min Yuk, Jin-Man Kim, Gyu Yong Song, Jichan Jang, Eun-Kyeong Jo
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 179, Iss , Pp 117313- (2024)
Mycobacteroides abscessus (Mabc) is a rapidly growing nontuberculous mycobacterium that poses a considerable challenge as a multidrug-resistant pathogen causing chronic human infection. Effective therapeutics that enhance protective immune responses
Externí odkaz:
https://doaj.org/article/559b67aedb1c4718a2c7b8ccb6033731
Autor:
Seungwha Paik, Kyeong Tae Kim, In Soo Kim, Young Jae Kim, Hyeon Ji Kim, Seunga Choi, Hwa-Jung Kim, Eun-Kyeong Jo
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Mycobacterial acyl carrier protein (AcpM; Rv2244), a key protein involved in Mycobacterium tuberculosis (Mtb) mycolic acid production, has been shown to suppress host cell death during mycobacterial infection. This study reports that mycobacterial Ac
Externí odkaz:
https://doaj.org/article/6c011169166f45eb809305748081c676
Autor:
Cho Rong Park, Seungwha Paik, Young Jae Kim, Jin Kyung Kim, Sang Min Jeon, Sang-Hee Lee, Jake Whang, Jinhua Cheng, Joo-Won Suh, Jin Cao, Gauri Shetye, Shao-Nong Chen, James McAlpine, Guido F. Pauli, Scott Franzblau, Sanghyun Cho, Eun-Kyeong Jo
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Nontuberculous mycobacterial pulmonary infection is often aggravated due to antibiotic resistance issues. There is a need for development of new drugs inducing both host immune responses and antimicrobial activities. This study shows that the rufomyc
Externí odkaz:
https://doaj.org/article/5fe2dd3be68a4884a1388e2c8d277c93
Publikováno v:
Virulence, Vol 10, Iss 1, Pp 448-459 (2019)
Tuberculosis (TB), which is primarily caused by the major etiologic agent Mycobacterium tuberculosis (Mtb), remains a serious infectious disease worldwide. Recently, much effort has been made to develop novel/improved therapies by modulating host res
Externí odkaz:
https://doaj.org/article/de0335e6d15941d2b260ba708ac1f1cc
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Mycobacterium tuberculosis (Mtb) is an intracellular pathogen causing human tuberculosis, an infectious disease that still remains as a global health problem. Autophagy, a lysosomal degradative process, has emerged as a critical pathway to restrict i
Externí odkaz:
https://doaj.org/article/865ca5464f1b46a9bea0bbaafa54c3d9
An Interplay Between Autophagy and Immunometabolism for Host Defense Against Mycobacterial Infection
Autor:
Seungwha Paik, Eun-Kyeong Jo
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Autophagy, an intracellular catabolic pathway featuring lysosomal degradation, is a central component of the host immune defense against various infections including Mycobacterium tuberculosis (Mtb), the pathogen that causes tuberculosis. Mtb can eva
Externí odkaz:
https://doaj.org/article/f8742005831848079905f0ada3ecb6a4
Publikováno v:
Cells, Vol 9, Iss 9, p 1979 (2020)
Autophagy is an intracellular process that targets intracellular pathogens for lysosomal degradation. Autophagy is tightly controlled at transcriptional and post-translational levels. Nuclear receptors (NRs) are a family of transcriptional factors th
Externí odkaz:
https://doaj.org/article/dfbd71abdbb945b983fe8e11fd23630b
Publikováno v:
Journal of Bacteriology and Virology. 50:203-217
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::272314ee019eec2fd00a3d4057afb269
https://doi.org/10.4167/jbv.2020.50.4.203
https://doi.org/10.4167/jbv.2020.50.4.203
Autor:
Cho Rong Park, Seungwha Paik, Young Jae Kim, Jin Kyung Kim, Sang Min Jeon, Sang-Hee Lee, Jake Whang, Jinhua Cheng, Joo-Won Suh, Jin Cao, Gauri Shetye, Shao-Nong Chen, James McAlpine, Guido F. Pauli, Scott Franzblau, Sanghyun Cho, Eun-Kyeong Jo
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Nontuberculous mycobacterial pulmonary infection is often aggravated due to antibiotic resistance issues. There is a need for development of new drugs inducing both host immune responses and antimicrobial activities. This study shows that the rufomyc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61db93721cdef0bacddb8511643f2510
Autor:
Jooyeon Lee, Eun-Kyeong Jo, Young Jae Kim, Sung-Gwon Lee, Yeon Sook Kim, Prashanta Silwal, Chaeuk Chung, Seungwha Paik, Kyung Mok Sohn, Chungoo Park, Hyeongseok Jeong, Shinhyea Cheon, Hyeon Ji Kim, In Soo Kim
Publikováno v:
Journal of Korean Medical Science
Background Observational studies of the ongoing coronavirus disease 2019 (COVID-19) outbreak suggest that a ‘cytokine storm’ is involved in the pathogenesis of severe illness. However, the molecular mechanisms underlying the altered pathological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a5df3a918b39e66a576a059c25c7b9f
https://doi.org/10.3346/jkms.2020.35.e343
https://doi.org/10.3346/jkms.2020.35.e343