Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Seunglee Kwon"'
Autor:
Byeong Hoon Oh, Jueun Jeon, Jae Hyung Park, Van Quy Nguyen, Chan Ho Kim, Seunglee Kwon, Wooram Um, Dong Gil You, Jae Yoon An
Publikováno v:
International Journal of Biological Macromolecules. 192:1231-1239
Anti-death receptor 5 (DR5) antibody is a potential therapeutic agent for liver fibrosis because it exhibits anti-fibrotic effects by inducing the apoptosis of activated hepatic stellate cells (HSCs), which are responsible for hepatic fibrogenesis. H
Autor:
Han Young Kim, Seunglee Kwon, Wooram Um, Sol Shin, Chan Ho Kim, Jae Hyung Park, Byung‐Soo Kim
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 18(36)
The unique biological characteristics and promising clinical potential of extracellular vesicles (EVs) have galvanized EV applications for regenerative medicine. Recognized as important mediators of intercellular communication, naturally secreted EVs
Publikováno v:
Accounts of Chemical Research. 52:1771-1782
Growth in the knowledge of cancer biology has led to the emergence and evolution of cancer nanomedicines by providing the rationale for leveraging nanotechnology to develop better treatment options. The discovery of nanometer-sized intercellular open
Autor:
Doo Sung Lee, Jueun Jeon, Sol Shin, V. G. Deepagan, Eun Sook Lee, Minah Suh, Wooram Um, Soyoung Son, Hyewon Ko, Jae Hyung Park, Jiwoong Min, Seunglee Kwon
Publikováno v:
Acta Biomaterialia. 79:294-305
Since delivering drugs to an entire tumoral region leads to high therapeutic efficacy and good prognosis, achieving deep tumoral penetration of drugs is a major issue in cancer treatment. In this regard, conventional nanomedicines (50 nm) have shown
Autor:
Deok Ho Kim, Yong Woo Cho, Byeong Hoon Oh, Van Dat Bui, Seunglee Kwon, Jae Hyung Park, Minjae Do, Yeari Song, Sol Shin, Eun Sook Lee, Dong-Gyu Jo
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 330
The biological significance of extracellular vesicles (EVs) as intercellular communication mediators has been increasingly revealed in a wide range of normal physiological processes and disease pathogenesis. In particular, regenerative and immunomodu
Autor:
Gyeong Taek Lim, Jungmi Lee, Wooram Um, Jae Hyung Park, Dong Gil You, Yong Woo Cho, Byeong Hoon Oh, Dong-Gyu Jo, Seok Ho Song, Seunglee Kwon
Publikováno v:
Science Advances
Surface engineering of exosomes enhances the therapeutic efficacy of rheumatoid arthritis by macrophage reprogramming.
Despite the remarkable advances in therapeutics for rheumatoid arthritis (RA), a large number of patients still lack effective
Despite the remarkable advances in therapeutics for rheumatoid arthritis (RA), a large number of patients still lack effective
Autor:
Sol Shin, Chan Ho Kim, Jeongjin Lee, Wooram Um, Jae Hyung Park, Jueun Jeon, Dong Gil You, Seunglee Kwon
Publikováno v:
Science Advances
CRET-based nanoparticles are useful for photoacoustic imaging and photodynamic therapy of cancer.
Chemiluminescence (CL) has recently gained attention for CL resonance energy transfer (CRET)–mediated photodynamic therapy of cancer. However, th
Chemiluminescence (CL) has recently gained attention for CL resonance energy transfer (CRET)–mediated photodynamic therapy of cancer. However, th
Autor:
Jun Gi Rho, Juhwan Yoon, Siyoung Yang, Jae Hyung Park, Ji Hye Han, Hwa Seung Han, Hansang Lee, Sungeun Heo, Eunyoung Lee, Hoin Kang, Van Quy Nguyen, Wook Kim, Eun Kyung Lee, Seunglee Kwon, Wang Hee Lee, Han Ho Shin
Publikováno v:
Journal of Controlled Release. 279:89-98
Self-assembled hyaluronic acid nanoparticles (HA-NPs) have been extensively investigated for biomedical and pharmaceutical applications owing to their biocompatibility and receptor-binding properties. Here, we report that an empty HA-NP itself not be
Autor:
Sol Shin, Seunglee Kwon, Soyoung Son, Jae Hyung Park, Hyewon Ko, Wooram Um, Jueun Jeon, V. G. Deepagan, Jun Young Lee, N. Vijayakameswara Rao
Publikováno v:
International Journal of Biological Macromolecules. 110:406-415
Trop2, a transmembrane glycoprotein, has emerged as a biomarker for targeted cancer therapy since it is overexpressed in 80% of triple negative breast cancer (TNBC) patients. For the site-specific delivery of the anticancer drug into TNBC, anti-Trop2
Autor:
Minah Suh, Jeongjin Lee, So Hee Lee, Wooram Um, Ki Young Choi, Sol Shin, Hyewon Ko, Sang Kyoon Kim, Jiwoong Min, Seunglee Kwon, Jae Hyung Park, V. G. Deepagan, N. Vijayakameswara Rao
Publikováno v:
Nano Letters. 18:2637-2644
Conventional cancer targeting with nanoparticles has been based on the assumed enhanced permeability and retention (EPR) effect. The data obtained in clinical trials to date, however, have rarely supported the presence of such an effect. To address t