Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Seunghwan Lim"'
Autor:
Seunghwan Lim, Eunjin Bae, Hae-Suk Kim, Tae-Aug Kim, Kyunghee Byun, Byungchul Kim, Suntaek Hong, Jong Pil Im, Chohee Yun, Bona Lee, Bonghee Lee, Seok Hee Park, John Letterio, Seong-Jin Kim
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32705 (2012)
Transforming growth factor-β1 (TGF-β1) is an important anti-inflammatory cytokine that modulates and resolves inflammatory responses. Recent studies have demonstrated that inflammation enhances neoplastic risk and potentiates tumor progression. In
Externí odkaz:
https://doaj.org/article/0e06b70793b14a8a86f32347f9a289df
The Planck list of high-redshift source candidates (the PHz catalogue) contains 2151 peaks in the cosmic infrared background, unresolved by Planck's 5 arcmin beam. Follow-up spectroscopic observations have revealed that some of these objects are $z \
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ae9d5487c2e71f4f312f860d712488
http://arxiv.org/abs/2204.06752
http://arxiv.org/abs/2204.06752
Autor:
Seunghwan Lim1 sxl269@case.edu, Byoung Kwon Yoo2 bk1003@gmail.com, Hae-Suk Kim1 hxk119@case.edu, Gilmore, Hannah L.3 hannah.gilmore@uhhospitals.org, Yonghun Lee4 yxl593@case.edu, Hyun-pil Lee3 hxl204@case.edu, Seong-Jin Kim5 kimsj@cha.ac.kr, Letterio, John1 john.letterio@case.edu, Hyoung-gon Lee3 hyoung-gon.lee@case.edu
Publikováno v:
BMC Cancer. 2014, Vol. 14 Issue 1, p1-24. 24p.
Autor:
Seunghwan Lim, Seok Hee Park, Seong-Jin Kim, Eun Kyung Lee, Suntaek Hong, Xiao-Jing Wang, Youn Sook Lee, Allen G. Li, Chan Lee
Publikováno v:
Nature Immunology. 8:504-513
Transforming growth factor-beta1 (TGF-beta1) regulates inflammation and can inhibit activation of the transcription factor NF-kappaB in certain cell types. Here we show that the TGF-beta-induced signaling protein Smad7 bound to TAB2 and TAB3, which a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d45bbac9519edae82e13468eba33ae00
https://doi.org/10.1038/ni1451
https://doi.org/10.1038/ni1451
Autor:
Jae Hong Kim, Fang Liu, Byung-Chul Kim, Seong Ji Park, Seong-Jin Kim, Woo Kwang Jeon, Eun Ji Jo, John J. Letterio, Young K. Lee, Seunghwan Lim, Jiyeon Choi
Publikováno v:
Oncotarget
Leukotriene B4 (LTB4) is a potent pro-inflammatory eicosanoid that is derived from arachidonic acid, and its signaling is known to have a tumor-promoting role in several cancer types. In this study, we investigated whether enhanced LTB4 signaling con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333d54733bfba7b0423b6bd0ef74e367
https://pubmed.ncbi.nlm.nih.gov/26497676
https://pubmed.ncbi.nlm.nih.gov/26497676
Publikováno v:
Journal of Biological Chemistry. 280:42097-42105
The serine/threonine kinase Mirk/dyrk1B is activated in several solid tumors where it mediates cell survival, but the mechanism by which Mirk is activated in tumors is unknown. We now demonstrate that Mirk is activated as a kinase by signaling from R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc90f57a7555aefc3363e5993fdab9e1
https://doi.org/10.1074/jbc.m507301200
https://doi.org/10.1074/jbc.m507301200
Autor:
Seunghwan Lim, Xiaobing Deng, Eileen Friedman, Daina Z. Ewton, Stephen E. Mercer, Thomas R. Mazur
Publikováno v:
Journal of Biological Chemistry. 280:25788-25801
The kinase Mirk/dyrk1B is essential for the differentiation of C2C12 myoblasts. Mirk reinforces the G0/G1 arrest state in which differentiation occurs by directly phosphorylating and stabilizing p27(Kip1) and destabilizing cyclin D1. We now demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::057cba174dbb016ea901fb120c891326
https://doi.org/10.1074/jbc.m413594200
https://doi.org/10.1074/jbc.m413594200
Publikováno v:
International Journal of Cancer. 103:21-28
Mirk/dyrk1B is an arginine-directed protein kinase, which functions as a transcriptional activator and mediates serum-free growth of colon carcinoma cells by an unknown mechanism. We now report that turnover of the cdk inhibitor p27(kip1) and the G(1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a55d14108b4cb2a8a4e431e99df80f6a
https://doi.org/10.1002/ijc.10743
https://doi.org/10.1002/ijc.10743
Autor:
Yong-Hun Lee, Seong-Jin Kim, Byoung Kwon Yoo, Hyun-Pil Lee, Hyoung Gon Lee, Hae-Suk Kim, John J. Letterio, Hannah Gilmore, Seunghwan Lim
Publikováno v:
BMC Cancer
Background Amyloid-β precursor protein (APP) is a highly conserved single transmembrane protein that has been linked to Alzheimer disease. Recently, the increased expression of APP in multiple types of cancers has been reported where it has signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f38270d6e3a929a548739a647dac20bb
https://doi.org/10.1186/1471-2407-14-928
https://doi.org/10.1186/1471-2407-14-928
Publikováno v:
Cancer Letters. 133:143-149
A human gene, nm23-H1, has been known as a metastasis suppressor in many tumor cells. The cellular mechanisms by which the nm23-H1 protein may directly or indirectly modulate the metastatic phenotype are not yet known. In this study the phenotypic ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a971326a6fc6f280fa7c55cb7088abad
https://doi.org/10.1016/s0304-3835(98)00219-5
https://doi.org/10.1016/s0304-3835(98)00219-5