Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Seungho Jun"'
Autor:
Fang Liu, Xiaoyan Cheng, Yingjie Wang, Kai Li, Tianliang Peng, Ningning Fang, Kalyan K. Pasunooti, Seungho Jun, Xiaomei Yang, Jianbo Wu
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Remimazolam tosilate is a new ultra-short-acting benzodiazepine sedative medicine. In this study, we evaluated the effect of remimazolam tosilate on the incidence of hypoxemia during sedation in elderly patients undergoing gastrointestina
Externí odkaz:
https://doaj.org/article/0ce52bbfadb64b4e89c782b1abf67bcb
Autor:
Kirill V Tarasov, Khalid Chakir, Daniel R Riordon, Alexey E Lyashkov, Ismayil Ahmet, Maria Grazia Perino, Allwin Jennifa Silvester, Jing Zhang, Mingyi Wang, Yevgeniya O Lukyanenko, Jia-Hua Qu, Miguel Calvo-Rubio Barrera, Magdalena Juhaszova, Yelena S Tarasova, Bruce Ziman, Richard Telljohann, Vikas Kumar, Mark Ranek, John Lammons, Rostislav Bychkov, Rafael de Cabo, Seungho Jun, Gizem Keceli, Ashish Gupta, Dongmei Yang, Miguel A Aon, Luigi Adamo, Christopher H Morrell, Walter Otu, Cameron Carroll, Shane Chambers, Nazareno Paolocci, Thanh Huynh, Karel Pacak, Robert Weiss, Loren Field, Steven J Sollott, Edward G Lakatta
Publikováno v:
eLife, Vol 11 (2022)
Adult (3 month) mice with cardiac-specific overexpression of adenylyl cyclase (AC) type VIII (TGAC8) adapt to an increased cAMP-induced cardiac workload (~30% increases in heart rate, ejection fraction and cardiac output) for up to a year without sig
Externí odkaz:
https://doaj.org/article/14634285f8224aeeb9edfd895e31e4f8
Autor:
Alex N. Smith, Raffaele Altara, Ghadir Amin, Nada J. Habeichi, Daniel G. Thomas, Seungho Jun, Abdullah Kaplan, George W. Booz, Fouad A. Zouein
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 15 (2022)
Heart failure with preserved ejection fraction (HFpEF) remains a medical anomaly that baffles researchers and physicians alike. The overall phenotypical changes of diastolic function and left ventricular hypertrophy observed in HFpEF are definable; h
Externí odkaz:
https://doaj.org/article/edb08a0509774eecb7a291f2141a747b
Autor:
Alessandro Cannavo, Seungho Jun, Giuseppe Rengo, Federica Marzano, Jacopo Agrimi, Daniela Liccardo, Andrea Elia, Gizem Keceli, Giovanna G. Altobelli, Lorenzo Marcucci, Aram Megighian, Erhe Gao, Ning Feng, Kai Kammers, Nicola Ferrara, Livio Finos, Walter J. Koch, Nazareno Paolocci
Publikováno v:
Circulation Research. 132:867-881
Background: Loss of brain-derived neurotrophic factor (BDNF)/TrkB (tropomyosin kinase receptor B) signaling accounts for brain and cardiac disorders. In neurons, β-adrenergic receptor stimulation enhances local BDNF expression. It is unclear if this
Autor:
Seungho Jun, Alessandro Cannavo, Giuseppe Rengo, Federica Marzano, Jacopo Agrimi, Gizem Keceli, Andrea Elia, Daniela Liccardo, Giovanna G. Altobelli, Erhe Gao, Ning Feng, Walter Koch, Nazareno Paolocci
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Cardiovascular Pharmacology.
Autor:
Zixiao Li, Seungho Jun, Krishna K. Singh, Patrick J. Calhoun, Gizem Keceli, Krishna Patel, Hikmet Kadioglu, Nazareno Paolocci, Giulio Agnetti
BackgroundThough acute mortality by myocardial infarction (MI) has declined in past decades, MI still represents one of the leading causes of heart failure (HF) development. We recently demonstrated the accumulation of toxic desmin aggregates in pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::823be2c42bba28bb2f80fa7ea3694d07
https://doi.org/10.1101/2023.05.09.540017
https://doi.org/10.1101/2023.05.09.540017
Autor:
Alessandro Cannavo, Seungho Jun, Giuseppe Rengo, Federica Marzano, Daniela Liccardo, Jacopo Agrimi, Andrea Elia, Gizem Keceli, Giovanna G. Altobelli, Lorenzo Marcucci, Aram Megighian, Erhe Gao, Ning Feng, Kai Kammers, Nicola Ferrara, Livio Finos, Walter J. Koch, Nazareno Paolocci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::221f8e4b7c20e7766eafc4790ccb6b35
https://hdl.handle.net/11588/914580
https://hdl.handle.net/11588/914580
Autor:
Kirill V Tarasov, Khalid Chakir, Daniel R Riordon, Alexey E Lyashkov, Ismayil Ahmet, Maria Grazia Perino, Allwin Jennifa Silvester, Jing Zhang, Mingyi Wang, Yevgeniya O Lukyanenko, Jia-Hua Qu, Miguel Calvo-Rubio Barrera, Magdalena Juhaszova, Yelena S Tarasova, Bruce Ziman, Richard Telljohann, Vikas Kumar, Mark Ranek, John Lammons, Rostislav Bychkov, Rafael de Cabo, Seungho Jun, Gizem Keceli, Ashish Gupta, Dongmei Yang, Miguel A Aon, Luigi Adamo, Christopher H Morrell, Walter Otu, Cameron Carroll, Shane Chambers, Nazareno Paolocci, Thanh Huynh, Karel Pacak, Robert Weiss, Loren Field, Steven J Sollott, Edward G Lakatta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1894a8ea0d2bfaa8df43234a7e7771be
https://doi.org/10.7554/elife.80949.sa2
https://doi.org/10.7554/elife.80949.sa2
Publikováno v:
Circulation Research. 131
Introduction: Post-translational modifications of cardiac troponin I (cTnI), an essential sarcomeric protein, have been known to play a vital role in regulating heart function. Site-specific phosphorylation on cTnI Ser199 is upregulated in human isch
Autor:
Nazareno Paolocci, Brittany Dunkerly-Eyring, Seungho Jun, Usman A. Tahir, Christian U. Oeing, Mark J. Ranek, Sumita Mishra, Robert E. Gerszten, Anna Chen, David A. Kass, Maria I. Grajeda
Publikováno v:
Circulation Research. 128:639-651
Rationale: The mTORC1 (mechanistic target of rapamycin complex-1) controls metabolism and protein homeostasis and is activated following ischemia reperfusion (IR) injury and by ischemic preconditioning (IPC). However, studies vary as to whether this