Výsledky vyhledávání - "Seungbyn Baek"

Akademický článek

Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas

Autor: Wei E. Gordon, Seungbyn Baek, Hai P. Nguyen, Yien-Ming Kuo, Rachael Bradley, Sarah L. Fong, Nayeon Kim, Alex Galazyuk, Insuk Lee, Melissa R. Ingala, Nancy B. Simmons, Tony Schountz, Lisa Noelle Cooper, Ilias Georgakopoulos-Soares, Martin Hemberg, Nadav Ahituv

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-23 (2024)

Abstract Frugivory evolved multiple times in mammals, including bats. However, the cellular and molecular components driving it remain largely unknown. Here, we use integrative single-cell sequencing (scRNA-seq and scATAC-seq) on insectivorous (Eptes

Externí odkaz: https://doaj.org/article/63321723d9924faaa1c76d697644b935

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Akademický článek

Single-cell analysis reveals cellular and molecular factors counteracting HPV-positive oropharyngeal cancer immunotherapy outcomes

Autor: Hye Ryun Kim, Da Hee Kim, Jung Eun Lee, Chang Gon Kim, Gamin Kim, Seyeon Park, Sang-Jun Ha, Jae-Won Cho, Martin Hemberg, Junha Cha, Euijeong Sung, Seungbyn Baek, Min Hee Hong, Nam Suk Sim, Hyun Jun Hong, Sun Ock Yoon, Yoon Woo Koh, Insuk Lee

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 12, Iss 6 (2024)

Background Oropharyngeal squamous cell carcinoma (OPSCC) induced by human papillomavirus (HPV-positive) is associated with better clinical outcomes than HPV-negative OPSCC. However, the clinical benefits of immunotherapy in patients with HPV-positive

Externí odkaz: https://doaj.org/article/41f10413d0f440bdbb6c94e5f872b2a8

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Akademický článek

Author Correction: Integrative single-cell characterization of a frugivorous and an insectivorous bat kidney and pancreas

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/fa5fd596502744f4b74fcbd8083c8533

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Akademický článek

Single-cell ATAC sequencing analysis: From data preprocessing to hypothesis generation

Autor: Seungbyn Baek, Insuk Lee

Publikováno v: Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1429-1439 (2020)

Most genetic variations associated with human complex traits are located in non-coding genomic regions. Therefore, understanding the genotype-to-phenotype axis requires a comprehensive catalog of functional non-coding genomic elements, most of which

Externí odkaz: https://doaj.org/article/788bfd8783e94120922d3adbdd131142

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Akademický článek

COVID-GWAB: A Web-Based Prediction of COVID-19 Host Genes via Network Boosting of Genome-Wide Association Data

Autor: Seungbyn Baek, Sunmo Yang, Insuk Lee

Publikováno v: Biomolecules, Vol 12, Iss 10, p 1446 (2022)

Host genetics affect both the susceptibility and response to viral infection. Searching for host genes that contribute to COVID-19, the Host Genetics Initiative (HGI) was formed to investigate the genetic factors involved in COVID-19 via genome-wide

Externí odkaz: https://doaj.org/article/d8c2901483bb4fa1b975ab03bb35bc72

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Integrative single-cell characterization of frugivory adaptations in the bat kidney and pancreas

Autor: Wei E. Gordon, Seungbyn Baek, Hai P. Nguyen, Yien-Ming Kuo, Rachael Bradley, Alex Galazyuk, Insuk Lee, Melissa R. Ingala, Nancy B. Simmons, Tony Schountz, Lisa Noelle Cooper, Ilias Georgakopoulos-Soares, Martin Hemberg, Nadav Ahituv

Publikováno v: bioRxiv

Frugivory evolved multiple times in mammals, including bats. However, the cellular and molecular components driving it remain largely unknown. Here, we used integrative single-cell sequencing on insectivorous and frugivorous bat kidneys and pancrease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6287ef2815add9e631b488097468364f
https://doi.org/10.1101/2023.02.12.528204

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HumanNet v3: an improved database of human gene networks for disease research

Autor: Sunmo Yang, Traver Hart, Chan Yeong Kim, Insuk Lee, Seungbyn Baek, Junha Cha, Eiru Kim, Edward M. Marcotte

Publikováno v: Nucleic Acids Research

Network medicine has proven useful for dissecting genetic organization of complex human diseases. We have previously published HumanNet, an integrated network of human genes for disease studies. Since the release of the last version of HumanNet, many

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f93bed5b2096ffbfe5c59ed87bc0a8ed
http://europepmc.org/articles/PMC8728227

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