Výsledky vyhledávání - "Seung-wook Shin"

Akademický článek

Developmental competence of interspecies cloned embryos produced using cells from large Japanese field mice (Apodemus speciosus) and oocytes from laboratory mice (Mus musculus domesticus)

Autor: Rika AZUMA, Yuki HATANAKA, Seung-Wook SHIN, Hitoshi MURAI, Minoru MIYASHITA, Masayuki ANZAI, Kazuya MATSUMOTO

Publikováno v: The Journal of Reproduction and Development, Vol 66, Iss 3, Pp 255-263 (2020)

The large Japanese field mouse (Apodemus speciosus) is endemic to Japan and may be used as an animal model for studies related to environmental pollution, medical science, and basic biology. However, the large Japanese field mouse has low reproductiv

Externí odkaz: https://doaj.org/article/c33c0d01a1ab41989176d50f3ffd26a6

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Akademický článek

Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis

Autor: Edgar-John Vogt, Keizo Tokuhiro, Min Guo, Ryan Dale, Guanghui Yang, Seung-Wook Shin, Maria Jimenez Movilla, Hari Shroff, Jurrien Dean

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)

Mammalian eggs require a single sperm for viable fertilization, and cortical granule exocytosis prevents additional sperm binding. Vogt et al. image at single granule resolution to document that cortical granule anchoring in the cortex ensures proper

Externí odkaz: https://doaj.org/article/e6424900b9c54c2f9956c43155b7d5da

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Akademický článek

Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice

Autor: Seung-Wook Shin, Edgar John Vogt, Maria Jimenez-Movilla, Boris Baibakov, Jurrien Dean

Publikováno v: Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)

During the maternal-to-zygotic transition there is degradation of maternal proteins via the ubiquitin-proteasome system (UPS). Here, the authors show that in the embryo the maternally inherited epigenetic factor DPPA3/Stella/PGC7 is cleavage by the U

Externí odkaz: https://doaj.org/article/973311f9c5ad4366a689137556ac9020

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Akademický článek

Perturbation of maternal PIASy abundance disrupts zygotic genome activation and embryonic development via SUMOylation pathway

Autor: Chika Higuchi, Mari Yamamoto, Seung-Wook Shin, Kei Miyamoto, Kazuya Matsumoto

Publikováno v: Biology Open, Vol 8, Iss 10 (2019)

During the maternal-to-zygotic transition (MZT), mRNAs and proteins stored in oocytes are degraded and zygotic genes are activated. We have previously shown that the ubiquitin-proteasome system (UPS)-mediated degradation of maternal proteins plays a

Externí odkaz: https://doaj.org/article/e8ac665f684345a8a2df74e374690f83

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Akademický článek

Author Correction: Anchoring cortical granules in the cortex ensures trafficking to the plasma membrane for post-fertilization exocytosis

Autor: Edgar-John Vogt, Keizo Tokuhiro, Min Guo, Ryan Dale, Guanghui Yang, Seung-Wook Shin, Maria Jimenez Movilla, Hari Shroff, Jurrien Dean

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

Externí odkaz: https://doaj.org/article/befea65ae3d0479cb08784c84bb87a48

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Akademický článek

Mouse zygote-specific proteasome assembly chaperone important for maternal-to-zygotic transition

Autor: Seung-Wook Shin, Natsumi Shimizu, Mikiko Tokoro, Satoshi Nishikawa, Yuki Hatanaka, Masayuki Anzai, Jun Hamazaki, Satoshi Kishigami, Kazuhiro Saeki, Yoshihiko Hosoi, Akira Iritani, Shigeo Murata, Kazuya Matsumoto

Publikováno v: Biology Open, Vol 2, Iss 2, Pp 170-182 (2012)

Summary During the maternal-to-zygotic transition (MZT), maternal proteins in oocytes are degraded by the ubiquitin–proteasome system (UPS), and new proteins are synthesized from the zygotic genome. However, the specific mechanisms underlying the U

Externí odkaz: https://doaj.org/article/a3b34855fdc1480fbb9cfc1200713357

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Akademický článek

GSE is a maternal factor involved in active DNA demethylation in zygotes.

Autor: Yuki Hatanaka, Natsumi Shimizu, Satoshi Nishikawa, Mikiko Tokoro, Seung-Wook Shin, Takuji Nishihara, Tomoko Amano, Masayuki Anzai, Hiromi Kato, Tasuku Mitani, Yoshihiko Hosoi, Satoshi Kishigami, Kazuya Matsumoto

Publikováno v: PLoS ONE, Vol 8, Iss 4, p e60205 (2013)

After fertilization, the sperm and oocyte genomes undergo extensive epigenetic reprogramming to form a totipotent zygote. The dynamic epigenetic changes during early embryo development primarily involve DNA methylation and demethylation. We have prev

Externí odkaz: https://doaj.org/article/891c151859394ecc86a19b89d11d51f7

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