Zobrazeno 1 - 10
of 324
pro vyhledávání: '"Seung-Soon Im"'
Autor:
Eun-Ho Lee, Jae-Ho Lee, Do-Young Kim, Young-Seung Lee, Yunju Jo, Tam Dao, Kyung Eun Kim, Dae-Kyu Song, Ji Hae Seo, Young-Kyo Seo, Je Kyung Seong, Changjong Moon, Eugene Han, Mi Kyung Kim, Seungwan Ryu, Minsang Shin, Gu Seob Roh, Hye Ra Jung, Timothy F. Osborne, Dongryeol Ryu, Tae-Il Jeon, Seung-Soon Im
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 4, Pp 1001-1012 (2024)
Abstract Sterol regulatory element-binding protein (SREBP)-1c is involved in cellular lipid homeostasis and cholesterol biosynthesis and is highly increased in nonalcoholic steatohepatitis (NASH). However, the molecular mechanism by which SREBP-1c re
Externí odkaz:
https://doaj.org/article/80e78e3a38c74985adacee329525bee4
Publikováno v:
Journal of Functional Foods, Vol 117, Iss , Pp 106218- (2024)
Inflammatory responses by macrophages have been pivotal in the pathogenesis of various diseases. We previously demonstrated the anti-inflammatory effects of ginsenoside compound K (GCK) through sirtuin 1 (SIRT1) activation in lipopolysaccharide-treat
Externí odkaz:
https://doaj.org/article/a17a75be1f234078a1dc4871e76ee2ad
Autor:
Jung-Hwan Baek, Myung Sup Kim, Hye Ryeon Jung, Min-Seon Hwang, Chan-ho Lee, Dai Hoon Han, Yong-ho Lee, Eugene C. Yi, Seung-Soon Im, Ilseon Hwang, Kyungeun Kim, Joon-Yong Chung, Kyung-Hee Chun
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 10, Pp 2324-2324 (2024)
Externí odkaz:
https://doaj.org/article/46323acdf991432a9163b10611f1bd61
Autor:
Cong Thuc Le, Giang Nguyen, So Young Park, Hanh Nguyen Dong, Yun Kyung Cho, Jae-Ho Lee, Seung-Soon Im, Dae-Hee Choi, Eun-Hee Cho
Publikováno v:
Endocrinology and Metabolism, Vol 38, Iss 4, Pp 395-405 (2023)
Background Hepatic stellate cells (HSCs) are the major cells which play a pivotal role in liver fibrosis. During injury, extracellular stimulators can induce HSCs transdifferentiated into active form. Phloretin showed its ability to protect the liver
Externí odkaz:
https://doaj.org/article/0f1be56a10954c598c47c6fb2de0777e
Autor:
Soo-Been Jeon, Hyebin Koh, A-Reum Han, Jieun Kim, Sunghun Lee, Jae-Ho Lee, Seung-Soon Im, Young-sup Yoon, Jong-Hee Lee, Ji Yoon Lee
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Red blood cell (RBC) generation from human pluripotent stem cells (PSCs) offers potential for innovative cell therapy in regenerative medicine as well as developmental studies. Ex vivo erythropoiesis from PSCs is currently limited by the low
Externí odkaz:
https://doaj.org/article/2b0edcb017f7431d97ebf6e3c32a580e
Autor:
Jung-Hwan Baek, Myung Sup Kim, Hye Ryeon Jung, Min-Seon Hwang, Chan-ho Lee, Dai Hoon Han, Yong-ho Lee, Eugene C. Yi, Seung-Soon Im, Ilseon Hwang, Kyungeun Kim, Joon-Yong Chung, Kyung-Hee Chun
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 7, Pp 1520-1530 (2023)
Abstract Nonalcoholic fatty liver disease (NAFLD) occurs due to the accumulation of fat in the liver, leading to fatal liver diseases such as nonalcoholic steatohepatitis (NASH) and cirrhosis. Elucidation of the molecular mechanisms underlying NAFLD
Externí odkaz:
https://doaj.org/article/fa3fd4008685464f806a79d36788d5e5
Publikováno v:
Gut and Liver, Vol 17, Iss 3, Pp 456-465 (2023)
Background/Aims: We explored whether high sodium intake, assessed by urinary excretion, determines the risk of sarcopenia and nonalcoholic fatty liver disease (NAFLD). Methods: We analyzed 10,036 adult participants with normal kidney function from th
Externí odkaz:
https://doaj.org/article/7fb3b1b573894f5084bebf02fdbba8a0
Autor:
Jae-Ho Lee, Sun Hee Lee, Eun-Ho Lee, Jeong-Yong Cho, Dae-Kyu Song, Young Jae Lee, Taeg Kyu Kwon, Byung-Chul Oh, Kae Won Cho, Timothy F. Osborne, Tae-Il Jeon, Seung-Soon Im
Publikováno v:
Journal of Advanced Research, Vol 45, Iss , Pp 1-13 (2023)
Introduction: Sterol regulatory element binding protein (SREBP) cleavage-associating protein (SCAP) is a sterol-regulated escort protein that translocates SREBPs from the endoplasmic reticulum to the Golgi apparatus, thereby activating lipid metaboli
Externí odkaz:
https://doaj.org/article/fa480bf32fcc444ab2cfb2d2d12b298f
Autor:
Seung Un Seo, Seon Min Woo, Seung-Soon Im, Younghoon Jang, Eugene Han, Sang Hyun Kim, Hongchan Lee, Hyun-Shik Lee, Ju-Ock Nam, Edward Gabrielson, Kyoung-jin Min, Taeg Kyu Kwon
Publikováno v:
Cell Death and Disease, Vol 13, Iss 2, Pp 1-13 (2022)
Abstract Cathepsin D (Cat D) is well known for its roles in metastasis, angiogenesis, proliferation, and carcinogenesis in cancer. Despite Cat D being a promising target in cancer cells, effects and underlying mechanism of its inhibition remain uncle
Externí odkaz:
https://doaj.org/article/7b38673b8e814d76a1ecfc3f03ada1f7
Publikováno v:
Experimental and Molecular Medicine, Vol 52, Iss 5, Pp 724-729 (2020)
Metabolic diseases: blocking fat and cholesterol production The complex cellular functions of a membrane protein that influences fat and cholesterol levels have been reviewed by researchers in South Korea. The main role of this protein, SCAP, is to m
Externí odkaz:
https://doaj.org/article/323bfc1d208a4e22bed27cd82d0bcd63