Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Seung-Joo Yang"'
Autor:
Hyunji Moon, Chanhyuk Min, Gayoung Kim, Deokhwan Kim, Kwanhyeong Kim, Sang-Ah Lee, Byeongjin Moon, Susumin Yang, Juyeon Lee, Seung-Joo Yang, Steve K. Cho, Gwangrog Lee, Chang Sup Lee, Chul-Seung Park, Daeho Park
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Calcium flux must be carefully controlled during the phagocytosis of apoptotic cells (efferocytosis), although how this occurs is not fully understood. Here, the authors show that the Cereblon E3 ligase regulates Orai1 degradation and subsequently SO
Externí odkaz:
https://doaj.org/article/e974b64c64804ac5944f1149649c6f51
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 512 (2021)
Cereblon (CRBN), a primary target of immune-modulatory imide drugs (IMiDs), functions as a substrate receptor in the CUL4-RBX1-DDB1-CRBN (known as CRL4CRBN) E3 ubiquitin ligase complex. Binding of IMiDs to CRBN redirects the CRL4CRBN E3 ubiquitin lig
Externí odkaz:
https://doaj.org/article/65432da45f4f47aebf32dc40c21a4792
Autor:
Nammi Park, Jubert Marquez, Trong Kha Pham, Tae Hee Ko, Jae Boum Youm, Min Kim, Seung Hak Choi, Jiyoung Moon, Jessa Flores, Kyung Soo Ko, Byoung Doo Rhee, Ippei Shimizu, Tohru Minamino, Jae Du Ha, Jong Yeon Hwang, Seung Joo Yang, Chul-Seung Park, Hyoung Kyu Kim, Jin Han
Publikováno v:
European Heart Journal. 43:1973-1989
Aims Cereblon (CRBN) is a substrate receptor of the E3 ubiquitin ligase complex that was reported to target ion channel proteins. L-type voltage-dependent Ca2+ channel (LTCC) density and dysfunction is a critical player in heart failure with reduced
Autor:
Kyung-Sik Lee, Hye-Seong Park, Guk-Yeol Park, Gi-Chan Lee, Eun-Ji Choi, Jae-in Yu, Seung-Joo Yang, Mihwa Kim, Yoonjoo Choi, Je-Jung Lee, Joon Haeng Rhee, Bum Chan Park, Jae Eun Park
Publikováno v:
Cancer Research. 82:6189-6189
[Purpose] Immunosuppressive tumor microenvironment (TME) is the major hurdle to cancer immunotherapy. Advanced hepatocellular carcinoma (aHCC) is one of the representative cold tumors with immunosuppressive TME and presents obvious correlation betwee
Publikováno v:
Pharmaceuticals, Vol 14, Iss 512, p 512 (2021)
Pharmaceuticals
Volume 14
Issue 6
Pharmaceuticals
Volume 14
Issue 6
Cereblon (CRBN), a primary target of immune-modulatory imide drugs (IMiDs), functions as a substrate receptor in the CUL4-RBX1-DDB1-CRBN (known as CRL4CRBN) E3 ubiquitin ligase complex. Binding of IMiDs to CRBN redirects the CRL4CRBN E3 ubiquitin lig
Autor:
Yun Kyung Kim, Uroos Akber, Chul-Seung Park, Seung-Joo Yang, Seungje Jeon, Sungsu Lim, Sunhwa Bong, Heeji Jo, Zee-Yong Park
Publikováno v:
J Neurosci
Protein aggregation can induce explicit neurotoxic events that trigger a number of presently untreatable neurodegenerative disorders. Chaperones, on the other hand, play a neuroprotective role due to their ability to unfold and refold abnormal protei
Publikováno v:
The FASEB Journal. 33
Publikováno v:
Korean Corporation Management Review. 23:171-197
Autor:
Akber, Uroos, Heeji Jo, Seungje Jeon, Seung-Joo Yang, Sunhwa Bong, Sungsu Lim, Yun Kyung Kim, Zee-Yong Park, Chul-Seung Park
Publikováno v:
Journal of Neuroscience; 6/16/2021, Vol. 41 Issue 24, p5138-5156, 19p
Publikováno v:
The FASEB Journal. 32