Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Seung-Hoi Koo"'
Publikováno v:
Experimental and Molecular Medicine, Vol 56, Iss 7, Pp 1552-1559 (2024)
Abstract It has long been postulated that dietary restriction is beneficial for ensuring longevity and extending the health span of mammals, including humans. In particular, a reduction in protein consumption has been shown to be specifically linked
Externí odkaz:
https://doaj.org/article/ad5ba64cc5204101bb87db8990eceb4a
Autor:
Jaewon Lee, Jihoon Ha, Jun-Hyeong Kim, Dongyeob Seo, Minbeom Kim, Yerin Lee, Seong Shil Park, Dahee Choi, Jin Seok Park, Young Jae Lee, Siyoung Yang, Kyung-Min Yang, Su Myung Jung, Suntaek Hong, Seung-Hoi Koo, Yong-Soo Bae, Seong-Jin Kim, Seok Hee Park
Publikováno v:
Experimental and Molecular Medicine, Vol 55, Iss 6, Pp 1218-1231 (2023)
Abstract The signaling pathways governing acetaminophen (APAP)-induced liver injury have been extensively studied. However, little is known about the ubiquitin-modifying enzymes needed for the regulation of APAP-induced liver injury. Here, we examine
Externí odkaz:
https://doaj.org/article/1c46d3af0ff845178e5fd7a36536788b
Autor:
Hwa Young Lee, Geum-Hwa Lee, Kashi Raj Bhattarai, Byung-Hyun Park, Seung-Hoi Koo, Hyung-Ryong Kim, Han Jung Chae
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/367b59716f1041c9b2a96a97f61cdb9e
Autor:
Myeong-Suk Bahn, Dong-Min Yu, Myoungwoo Lee, Sung-Je Jo, Ji-Won Lee, Ho-Chul Kim, Hyun Lee, Hong Lim Kim, Arum Kim, Jeong-Ho Hong, Jun Seok Kim, Seung-Hoi Koo, Jae-Seon Lee, Young-Gyu Ko
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Bahn et al explore the role of the lipid raft protein Prominin-1 in liver regeneration. They show that Prominin-1 promotes hepatocyte proliferation after acute liver injury by interacting with the signal transducer GP130, confining it to lipid rafts
Externí odkaz:
https://doaj.org/article/44a2b730a3d24d5aa6b5b8449e0f3f16
Autor:
Hyun Lee, Dong-Min Yu, Myeong-Suk Bahn, Young-Jae Kwon, Min Jee Um, Seo Yeon Yoon, Ki-Tae Kim, Myoung-Woo Lee, Sung-Je Jo, Sungsoo Lee, Seung-Hoi Koo, Ki Hoon Jung, Jae-Seon Lee, Young-Gyu Ko
Publikováno v:
Experimental and Molecular Medicine, Vol 54, Iss 8, Pp 1277-1289 (2022)
Liver disease: Preventing progression of fibrosis Progression of liver fibrosis is kept in check by a regulatory protein that switches off a signaling pathway responsible for cell death and subsequent scar tissue formation. Liver fibrosis is a common
Externí odkaz:
https://doaj.org/article/ecd460ab468b4f3c9635a180af15e970
Autor:
Yeeun Choi, Min-Ji Song, Woong-Jae Jung, Haengdueng Jeong, Seokjae Park, Bobae Yang, Eun-Chong Lee, Jung-Sik Joo, Dahee Choi, Seung-Hoi Koo, Eun-Kyoung Kim, Ki Taek Nam, Hyoung-Pyo Kim
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 5, Pp 1761-1787 (2021)
Background & Aims: The liver is the major organ for metabolizing lipids, and malfunction of the liver leads to various diseases. Nonalcoholic fatty liver disease is rapidly becoming a major health concern worldwide and is characterized by abnormal re
Externí odkaz:
https://doaj.org/article/a2fe8b241c40454ab82a0f2c5a7e47ac
Publikováno v:
Diabetes & Metabolism Journal, Vol 44, Iss 4, Pp 498-508 (2020)
Cyclic adenosine monophosphate (cAMP) signaling is critical for regulating metabolic homeostasis in mammals. In particular, transcriptional regulation by cAMP response element-binding protein (CREB) and its coactivator, CREB-regulated transcription c
Externí odkaz:
https://doaj.org/article/6ac98d4a1f4b4e438213d61bb9984528
Autor:
Hye-Sook Han, Sang Gyune Kim, Young Seok Kim, Si-Hyong Jang, Yongmin Kwon, Dahee Choi, Tom Huh, Eunyoung Moon, Eunyong Ahn, Je Kyung Seong, Hee-Seok Kweon, Geum-Sook Hwang, Dae Ho Lee, Kae Won Cho, Seung-Hoi Koo
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101402- (2022)
Objective: Diet-induced obesity is often associated with nonalcoholic fatty liver disease (NAFLD), which instigates severe metabolic disorders, including cirrhosis, hepatocellular carcinoma, and type 2 diabetes. We have shown that hepatic depletion o
Externí odkaz:
https://doaj.org/article/7b787322d9f843c4ad7ec37dc28d4bb7
Autor:
Seung-Hoi Koo
Publikováno v:
Endocrinology and Metabolism, Vol 36, Iss 3, Pp 572-573 (2021)
Externí odkaz:
https://doaj.org/article/061238e233174362b39e7c14a3d600d9
Autor:
Jung-Hoon Pyun, Hyun-Ji Kim, Myong-Ho Jeong, Byeong-Yun Ahn, Tuan Anh Vuong, Dong I. Lee, Seri Choi, Seung-Hoi Koo, Hana Cho, Jong-Sun Kang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The mechanisms that regulate the activity of Ca2 +/calmodulin-dependent protein kinase II (CaMKII) in the context of heart failure are incompletely understood. Here the authors show that protein arginine methyltransferase 1 (PRMT1) prevents cardiac h
Externí odkaz:
https://doaj.org/article/af3a2e76bb0b4a2582ff80e76159a01c