Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Seung Y, Chu"'
Autor:
Christine Bonzon, Rumana Rashid, Irene Leung, Nicole Rodriguez, Alex Nisthal, Ruschelle Love, Sung-Hyung Lee, Panida Lertkiatmongkol, Sher Karki, Kendra N Avery, Norman J Barlow, Seung Y Chu, Gregory L Moore, John R Desjarlais
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/0bbc3f9cd59949e18f47f70a8c932be8
Autor:
Seung Y. Chu, Erik Pong, Christine Bonzon, Ning Yu, Chaim O. Jacob, Samantha A. Chalmers, Chaim Putterman, David E. Szymkowski, William Stohl
Publikováno v:
Journal of Translational Autoimmunity, Vol 4, Iss , Pp 100075- (2021)
Engagement of Fcγ receptor IIb (FcγRIIb) suppresses B cell activation and represents a promising target for therapy in autoimmunity. Obexelimab is a non-depleting anti-human CD19 mAb with an Fc region engineered to have high affinity for human Fcγ
Externí odkaz:
https://doaj.org/article/91722979a7e84632bcf95a6a9239fd8d
Autor:
Eugene A. Zhukovsky, John R. Desjarlais, Roland Repp, Patrick F. Joyce, Igor Vostiar, John O. Richards, Seung Y. Chu, Sher Karki, Matthias Peipp, Erik Pong, Matthew J. Bernett, Holly M. Horton
Supplementary Figure 1 from Potent In vitro and In vivo Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2413da5ba7c94cdaf17aec8c62e5aace
https://doi.org/10.1158/0008-5472.22375889
https://doi.org/10.1158/0008-5472.22375889
Autor:
Eugene A. Zhukovsky, John R. Desjarlais, Roland Repp, Patrick F. Joyce, Igor Vostiar, John O. Richards, Seung Y. Chu, Sher Karki, Matthias Peipp, Erik Pong, Matthew J. Bernett, Holly M. Horton
Supplementary Figure 2 from Potent In vitro and In vivo Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11125e1a698038f30d8ba2f8c030c832
https://doi.org/10.1158/0008-5472.22375886.v1
https://doi.org/10.1158/0008-5472.22375886.v1
Autor:
Eugene A. Zhukovsky, John R. Desjarlais, Roland Repp, Patrick F. Joyce, Igor Vostiar, John O. Richards, Seung Y. Chu, Sher Karki, Matthias Peipp, Erik Pong, Matthew J. Bernett, Holly M. Horton
Supplementary Figure Legends 1-3 from Potent In vitro and In vivo Activity of an Fc-Engineered Anti-CD19 Monoclonal Antibody against Lymphoma and Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c922c9b540c134dfce296948c2e7cc7
https://doi.org/10.1158/0008-5472.22375880
https://doi.org/10.1158/0008-5472.22375880
Autor:
Matthew A. Dragovich, Viralkumar Davra, Matthew S. Faber, Yoon Kyung Kim, Alex Nisthal, Veronica G. Zeng, Jonathan Jacinto, Juan E. Diaz, Thuy Truong, Jing Qi, Kendra N. Avery, Rumana Rashid, Sung-Hyung Lee, Seung Y. Chu, Christine Bonzon, Ruschelle Love, Matthew J. Bernett, James A. Ernst, Rena Bahjat, Norman J. Barlow, John R. Desjarlais, Michael Hedvat, Gregory L. Moore
Publikováno v:
Cancer Research. 83:2983-2983
T cells in the tumor micro-environment require TCR/MHC engagement and co-stimulatory receptor engagement to achieve optimal activation. Solid tumor cells lack expression of CD28 ligands, so we hypothesized that activation of CD28 signaling at the T c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d43bd9a9426cbc7ff5f24bbbfc11dd3d
https://doi.org/10.1158/1538-7445.am2023-2983
https://doi.org/10.1158/1538-7445.am2023-2983
Autor:
Alex Nisthal, Sung-Hyung Lee, Christine Bonzon, Ruschelle Love, Kendra N. Avery, Rumana Rashid, Panida Lertkiatmongkol, Nicole Rodriguez, Hanh Nguyen, Araz Eivazi, Sher Karki, Norm Barlow, Seung Y. Chu, Greg L. Moore, John R. Desjarlais
Publikováno v:
Cancer Research. 82:3515-3515
Interleukin-18 (IL18) is a proinflammatory cytokine that modulates both innate and adaptive immune responses. After processing of the inactive precursor within monocytes and macrophages, mature IL18 can promote the expansion, survival, and cytotoxici
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3a8831daf4864aeb32271492b54b19a
https://doi.org/10.1158/1538-7445.am2022-3515
https://doi.org/10.1158/1538-7445.am2022-3515
Autor:
Seung Y, Chu, Erik, Pong, Christine, Bonzon, Ning, Yu, Chaim O, Jacob, Samantha A, Chalmers, Chaim, Putterman, David E, Szymkowski, William, Stohl
Publikováno v:
Journal of Translational Autoimmunity
Engagement of Fcγ receptor IIb (FcγRIIb) suppresses B cell activation and represents a promising target for therapy in autoimmunity. Obexelimab is a non-depleting anti-human CD19 mAb with an Fc region engineered to have high affinity for human Fcγ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ef4e64a84708c78741f10b1ba46b4f4
https://pubmed.ncbi.nlm.nih.gov/33409482
https://pubmed.ncbi.nlm.nih.gov/33409482
Autor:
Umesh Muchhal, Christine Bonzon, John R. Desjarlais, Ke Liu, Rajat Varma, Nicole Rodriguez, Connie Ardila, Matthew J. Bernett, Rumana Rashid, Seung Y. Chu, Nargess Hassanzadeh-Kiabi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Interleukin-12 (IL12) is a proinflammatory cytokine produced by activated antigen-presenting cells that induces differentiation of Th1 cells and increased proliferation and cytotoxicity of T and NK cells. Stimulation of these cells by IL12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5051d0f78045aca825d98ef4bff0cc
https://doi.org/10.1136/jitc-2020-sitc2020.0564
https://doi.org/10.1136/jitc-2020-sitc2020.0564
Autor:
Christine Bonzon, James Ernst, John R. Desjarlais, Lukasz J. Ochyl, Gregory T. Moore, Rumana Rashid, Seung Y. Chu, Alex Nisthal, Kendra N. Avery, Erik Weiking Pong, Suzanne Schubbert
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background TGFβ production by solid tumors and their microenvironment is a major mechanism used by tumors to avoid immunosurveillance. Blockade of TGFβ has been shown to promote an anti-tumor response; however, systemic blockade of TGFβ has also b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05345db9ad5db71bec4181f3c17bb30f
https://doi.org/10.1136/jitc-2020-sitc2020.0714
https://doi.org/10.1136/jitc-2020-sitc2020.0714