Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Seung Pil Shin"'
Autor:
Soo-Yeon Kim, Whi-An Kwon, Seung-Pil Shin, Ho Kyung Seo, Soo-Jeong Lim, Yuh-Seog Jung, Hyo-Kyung Han, Kyung-Chae Jeong, Sang-Jin Lee
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 49-58 (2018)
In a previous report, 3-aminopropyl functionalized magnesium phyllosilicate (aminoclay) improved adenovirus transduction efficiency by shielding the negative surface charges of adenovirus particles. The present study analyzed the physicochemical char
Externí odkaz:
https://doaj.org/article/32c47b678cf54850954ffbfdb57e60be
Autor:
Sang-Jin Lee, Jeong Won Kang, Seung Hee Lee, Myeong-Cherl Kook, In-Hoo Kim, Seung-Pil Shin, Hark Kyun Kim
Publikováno v:
Cancer gene therapy. 26(5-6)
We conducted a phase 1 trial for single-dose intravenous Ad5CRT, a replication-defective adenovirus vector expressing HSVtk (herpes simplex virus thymidine kinase) modulated by a specific trans-splicing ribozyme that targets human telomerase reverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c846b8ea5440c74bfbacdfba76f57669
https://pubmed.ncbi.nlm.nih.gov/30393375
https://pubmed.ncbi.nlm.nih.gov/30393375
Autor:
Ho Kyung Seo, Soo-Yeon Kim, Seung-Pil Shin, Whi-An Kwon, Soo-Jeong Lim, Yuh-Seog Jung, Hyo-Kyung Han, Kyung-Chae Jeong, Sang-Jin Lee
Publikováno v:
Drug Delivery
Drug Delivery, Vol 25, Iss 1, Pp 49-58 (2018)
Drug Delivery, Vol 25, Iss 1, Pp 49-58 (2018)
In a previous report, 3-aminopropyl functionalized magnesium phyllosilicate (aminoclay) improved adenovirus transduction efficiency by shielding the negative surface charges of adenovirus particles. The present study analyzed the physicochemical char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de7ba8bc70e8909bb779314301ada27
https://pubmed.ncbi.nlm.nih.gov/29224371
https://pubmed.ncbi.nlm.nih.gov/29224371
Autor:
Kyung-Chae Jeong, Jeong Bin Seo, In-Hoo Kim, Sang Don Lee, Ho Kyung Seo, Jae-Kook Nam, Seung-Pil Shin, Sang-Jin Lee
Publikováno v:
Oncotarget
// Ho Kyung Seo 1 , Jeong Bin Seo 2 , Jae-Kook Nam 3 , Kyung-Chae Jeong 4 , Seung-Pil Shin 3 , In-Hoo Kim 5 , Sang Don Lee 2 and Sang-Jin Lee 3 1 Center for Prostate Cancer, Gyeonggi-do, Biomedical Research Institute, Pusan National University and Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513709230ccd53376eb359f112f9fcef
https://doi.org/10.18632/oncotarget.2151
https://doi.org/10.18632/oncotarget.2151
Autor:
Hye Hyun Seo, Seung Pil Shin, Hyung Bae Park, Sang-Jin Lee, Jae Hun Shin, In Hoo Kim, Hyeon Seok Eom, Dong Pyo Lim, Yong-Soo Bae, Kyungho Choi
Publikováno v:
Molecular Therapy. 21(3):688-695
Adenoviruses harboring the herpes simplex virus thymidine kinase (HSVtk) gene under the regulation of a trans-splicing ribozyme targeting human telomerase reverse transcriptase (hTERT-TR) show marked and specific antitumor activity. In addition to in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::687d6af36b4bdf57849ed05ebb1d4e63
Autor:
Chung-Soo Park, Sang-Jin Lee, Kyung-Tae Kim, In-Hoo Kim, Jin-Sook Jeong, Seok-Jun Kim, Yun-Hee Kim, Seung-Pil Shin, Hye-Hyun Seo, Daehong Kim
Publikováno v:
Cancer Letters. 320:72-80
This study attempts to combine two findings toward developing a rational strategy for improved therapy for glioma. One of the findings, made in this pre-clinical study, is that an hTERT-targeting ribozyme-controlled HSVtk gene (hTERT.Rz.HSVtk) exerts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::157eb1577cf2dafa212bdf024e81a00e
https://doi.org/10.1016/j.canlet.2012.01.029
https://doi.org/10.1016/j.canlet.2012.01.029
Autor:
Seung Pil Shin, Ye Hyeon Ahn, Kyung-Hee Chun, Ji Young Shin, Jaewhan Song, Sang-Jin Lee, Kang Duck Lee, Hwajung Yi
Publikováno v:
Clinical & Experimental Metastasis. 29:359-369
Aberrant activation of Signal Transducer and Activator of Transcription 3 (STAT3) signaling has been shown to be associated with uncontrolled cell proliferation and suppression of host-immune surveillance. Conversely, silencing STAT3 can have the dua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a555ec8a9a88fe9affb1df4a4572552
https://doi.org/10.1007/s10585-012-9458-4
https://doi.org/10.1007/s10585-012-9458-4
Autor:
Sang-Jin Lee, Seung Pil Shin, Chang Hwan Ryu, John H. Lee, Kyungho Choi, Yuh S. Jung, Na Rae Jung, Ah Ra Goh, Hyeon Seok Eom
Publikováno v:
Cancer letters. 356(2 Pt)
An adenovirus harboring the HSV thymidine kinase (HSVtk) gene under the regulation of a trans-splicing ribozyme that targets telomerase is cytotoxic to cancer cells because it inhibits DNA replication (Ad5mTR). Furthermore, it induces anti-tumor immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd930e922e18e4f25d597b92279a7334
https://pubmed.ncbi.nlm.nih.gov/25449436
https://pubmed.ncbi.nlm.nih.gov/25449436
Autor:
Mi Young Koo, Jiyoung Park, Sei Yoon Joo, Hyunbo Shim, Sue Goo Rhee, Jung Mi Lim, Dongmin Kang, Seung Pil Shin, Hyun Ae Woo, Junho Chung
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 111(17)
Signal transducer and activator of transcription 3 (STAT3) is a multifunctional protein that participates in signaling pathways initiated by various growth factors and cytokines. It exists in multiple forms including those phosphorylated on Tyr(705)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2f0b64f58e0d414dc847e505ec9370f
https://pubmed.ncbi.nlm.nih.gov/24733900
https://pubmed.ncbi.nlm.nih.gov/24733900
Autor:
Seung-Pil Shin, Hye-Hyun Seo, Kyung-Chae Jeong, In-Hoo Kim, Weon Seo Park, Min-Ju Ji, Kyung-Tae Kim, Kyung-Ohk Ahn, Sang-Jin Lee, Ho Kyung Seo
Publikováno v:
The Journal of urology. 191(2)
c-MYC is a promising target for cancer therapy but its use is restricted by unwanted, devastating side effects. We explored whether intravesical instillation of the c-MYC inhibitor KSI-3716 could suppress tumor growth in murine orthotopic bladder xen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8607187e9288caef94f7586fbd884003
https://pubmed.ncbi.nlm.nih.gov/23872029
https://pubmed.ncbi.nlm.nih.gov/23872029