Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Seung J. Kim"'
Autor:
Seung J. Kim, Matthew J. Cecchini, Elissa Woo, Nathashi Jayawardena, Daniel T. Passos, Frederick A. Dick, Marco Mura
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Fibrosing interstitial lung diseases (ILDs) encompass a diverse range of scarring disorders that lead to progressive lung failure. Previous gene expression profiling studies focused on idiopathic pulmonary fibrosis (IPF) and bulk tissue samp
Externí odkaz:
https://doaj.org/article/826d764040fa44a7b05c82414f916d94
Autor:
Ah J. Lee, Da E. Nam, Yu J. Choi, Seung W. Noh, Soo H. Nam, Hye J. Lee, Seung J. Kim, Gyun J. Song, Byung‐Ok Choi, Ki W. Chung
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Background Charcot–Marie–Tooth disease type 1A (CMT1A) and hereditary neuropathy with liability to pressure palsies (HNPP) are developed by duplication and deletion of the 17p12 (PMP22) region, respectively. Methods De novo rates were de
Externí odkaz:
https://doaj.org/article/fd6fa10346bf4094aadcbbfb4b7b085a
SummaryIn mammalian cells expression of repetitive genomic sequences is repressed by heterochromatin, underscoring the potential threat of repeat expression to cellular homeostasis. However, the specific consequences of ectopic repeat expression rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::461b6bcc65ab6eb207a161a13b2df242
https://doi.org/10.1101/2023.05.08.539798
https://doi.org/10.1101/2023.05.08.539798
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Paediatrics Publications
The Journal of Biological Chemistry
The Journal of Biological Chemistry
The retinoblastoma tumour suppressor protein (RB) plays an important role in biological processes such as cell cycle control, DNA damage repair, epigenetic regulation, and genome stability. The canonical model of RB regulation is that cyclin-CDKs pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9be0b63c79d03d1f4bc3942d5d930d0
https://ir.lib.uwo.ca/paedpub/1152
https://ir.lib.uwo.ca/paedpub/1152
Publikováno v:
Paediatrics Publications
PD-L1 plays a central role in immune recognition of cancer cells. In this issue of Molecular Cell, Jin et al. (2019) report that a phosphorylated retinoblastoma protein contacts the DNA-binding domain of p65 NF-kB, thereby blocking transcription of P
Autor:
Aren E. Marshall, Ian Welch, Sara Ferwati, Seung J. Kim, William A. MacDonald, Matthew J. Cecchini, Daniel Thompsen Passos, Frederick A. Dick, Mellissa R.W. Mann, Charles A. Ishak, Christopher J. Howlett, Carlee R. White, Seth M. Rubin
Publikováno v:
Molecular cell, vol 64, iss 6
Paediatrics Publications
Paediatrics Publications
Repetitive genomic regions include tandem sequence repeats and interspersed repeats, such as endogenous retroviruses and LINE-1 elements. Repressive heterochromatin domains silence expression of these sequences through mechanisms that remain poorly u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03240ea1e97fba935deb729624292e32
https://escholarship.org/uc/item/93w8n658
https://escholarship.org/uc/item/93w8n658
Autor:
Hwangseo Park, Yong-Sam Kim, Seung J. Kim, Jeong H. Ko, Ju H. Kim, Keum Ran Yu, Byoung Chul Park, Suk-Kyeong Jung
Publikováno v:
Chemical Biology & Drug Design. 78:642-650
Despite a series of persuasive experimental evidence for the involvement of eyes absent protein tyrosine phosphatases in various human cancers, no small-molecule inhibitor has been reported so far. We have identified seven novel inhibitors of eyes ab
Autor:
Kim, Seung J.1,2 (AUTHOR) seung.kim@lhsc.on.ca, Cecchini, Matthew J.3 (AUTHOR), Woo, Elissa3 (AUTHOR), Jayawardena, Nathashi1,2 (AUTHOR), Passos, Daniel T.2,3,4 (AUTHOR), Dick, Frederick A.2,3,4 (AUTHOR), Mura, Marco1,5 (AUTHOR)
Publikováno v:
Scientific Reports. 11/2/2024, Vol. 14 Issue 1, p1-15. 15p.
Publikováno v:
Journal of Korean Society for Atmospheric Environment. 24:16-29
Nitrous acid (HONO) can be produced by heterogenous reactions of nitrogen dioxide on surface materials and direct emission from combustion sources. However, a little is known of indoor HONO levels or the relationship between residential HONO, NO, and