Výsledky vyhledávání - "Seung Hyun Baik"

Akademický článek

The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells

Autor: Shaheen Kabir, Justin Cidado, Courtney Andersen, Cortni Dick, Pei-Chun Lin, Therese Mitros, Hong Ma, Seung Hyun Baik, Matthew A Belmonte, Lisa Drew, Jacob E Corn

Publikováno v: eLife, Vol 8 (2019)

Overexpression of anti-apoptotic proteins MCL1 and Bcl-xL are frequently observed in many cancers. Inhibitors targeting MCL1 are in clinical development, however numerous cancer models are intrinsically resistant to this approach. To discover mechani

Externí odkaz: https://doaj.org/article/255dcd169e574cc1a6d33cba784a1b2d

Zobrazit plný text záznamu

Supratotal Resection of Glioblastoma: Better Survival Outcome than Gross Total Resection

Autor: Seung Hyun Baik, So Yeon Kim, Young Cheol Na, Jin Mo Cho

Publikováno v: Journal of Personalized Medicine. 13:383

Objective: Supratotal resection (SupTR) of glioblastoma allows for a superior long-term disease control and increases overall survival. On the other hand, aggressive conventional approaches, including gross total resections (GTR), are limited by the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ede37cf052638949420662ebbdf67227
https://doi.org/10.3390/jpm13030383

Zobrazit plný text záznamu

Supratotal Resection of Glioblastoma Allows Better Survival Outcomes Than Gross Total Resection

Autor: Seung Hyun Baik, Jin Mo Cho, Young Chul Na, So Yeon Kim

Objective: Supra-total resection (SupTR) of glioblastoma allows superior long-term disease control and increases overall survival. On the other hand, aggressive conventional approaches, including gross total resections (GTR), are limited by the impai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b9683805b381678247d589c75ff922
https://doi.org/10.21203/rs.3.rs-597119/v2

Zobrazit plný text záznamu

The CUL5 ubiquitin ligase complex mediates resistance to CDK9 and MCL1 inhibitors in lung cancer cells

Autor: Matthew A. Belmonte, Hong Ma, Lisa Drew, Seung Hyun Baik, Pei-Chun Lin, Justin Cidado, Courtney L. Andersen, Cortni Dick, Shaheen Kabir, Therese Mitros, Jacob E. Corn

Publikováno v: eLife, 8
eLife, Vol 8 (2019)
eLife

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::670ff4f56c3c1de9afa65a8992a20d29

Zobrazit plný text záznamu

Abstract A1-61: ANT2 shRNA downregulates multiple onco-miRNAs through the targets, TIMP-2, and suppresses cell death in human hepatocellular carcinoma cells

Autor: Seung Hyun Baik, Chul Woo Kim, Jong Kuen Lee

Publikováno v: Cancer Research. 75:A1-61

Micro RNA (miRNAs) are negative regulators of gene expression functioning either as tumor suppressors or oncogenes in cancer. As expression patterns of miRNAs and their role in the pathogenesis of hepatocellular carcinoma (HCC) are still poorly under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0854558de9fa9653759420c647d39d1f
https://doi.org/10.1158/1538-7445.transcagen-a1-61

Zobrazit plný text záznamu

Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon Cancer

Autor: Nancy Krett, Seung Hyun Baik, Arundhati Jana, Faraz Bishehsari, Jonas J. Staudacher, Barbara Jung, Seong Hoon Park, Jessica Bauer, Cemal Yazici, Özkan Özden, Judith C. Sporn

Publikováno v: Scientific Reports

BRCA1-associated RING domain protein 1 (BARD1) stabilizes BRCA1 protein by forming a heterodimeric RING-RING complex and impacts function of BRCA1, including homologous recombination (HR) repair. Although colon cancer cells usually express wild type

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6d371fe9f563a004748328313fd7550
https://pubmed.ncbi.nlm.nih.gov/27197561

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání