Zobrazeno 1 - 10
of 200
pro vyhledávání: '"Seung Goo Kang"'
Autor:
Dong-Hyun Kim, Kyeong-Jin Lee, JinJoo Park, Susan Chi, Jaekyu Han, Yewon Bang, Sun-Mi Kim, Seung Goo Kang, Sang-Hoon Cha, Yong-Hyun Han
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115587- (2023)
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by progressive inflammation and fibrosis around intrahepatic and extrahepatic bile ducts leading to severe hepatic cirrhosis and high mortality. Although there
Externí odkaz:
https://doaj.org/article/345c4fb9891b45f9a684528372adcdf1
Autor:
Jun Xie, Ying Du, Dewang Liu, Jianfeng Wu, Kang Yang, Xiaoyu He, Jiayi Zhao, Peicheng Hong, Kunyu Liao, Huanrong Zhang, Yazhen Hong, John R. Teijaro, Seung Goo Kang, Changchun Xiao, Wen-Hsien Liu
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112968- (2023)
Summary: The miR-17∼92 family microRNAs (miRNAs) play a key role in germinal center (GC) reaction through promoting T follicular helper (TFH) cell differentiation. It remains unclear whether they also have intrinsic functions in B cell differentiat
Externí odkaz:
https://doaj.org/article/4840eac0546146ffbc02268b340bfaf1
Autor:
Huijeong Ahn, Byung-Cheol Han, Jeongeun Kim, Seung Goo Kang, Pyeung-Hyeun Kim, Kyoung Hwa Jang, Seung Ho So, Seung-Ho Lee, Geun-Shik Lee
Publikováno v:
Journal of Ginseng Research, Vol 43, Iss 2, Pp 291-299 (2019)
Background: Ginsenosides of Korean Red Ginseng extracts (RGE) and its saponin components suppress secretion of inflammasome-mediating cytokines, whereas the nonsaponin fraction (NS) of RGE oppositely stimulates cytokine secretion. Although direct exp
Externí odkaz:
https://doaj.org/article/2937e806f6c748519042e85886271c81
Autor:
Minsik Park, Seunghwan Choi, Suji Kim, Joohwan Kim, Dong-Keon Lee, Wonjin Park, Taesam Kim, Jiwon Jung, Jong Yun Hwang, Moo-Ho Won, Sungwoo Ryoo, Seung Goo Kang, Kwon-Soo Ha, Young-Guen Kwon, Young-Myeong Kim
Publikováno v:
Experimental and Molecular Medicine, Vol 51, Iss 2, Pp 1-12 (2019)
Vascular disease: Small RNA as a possible culprit The overexpression of a microRNA molecule adversely affects the functioning of vascular smooth muscle cells (VSMCs) and may contribute to the development of artherosclerosis and preeclampsia. The inte
Externí odkaz:
https://doaj.org/article/2d17cb41f5d04569afe414a75c64d301
Autor:
Yunseo Woo, Hyo-Ji Lee, Jeongyeon Kim, Seung Goo Kang, Sungjin Moon, Jeong A. Han, Young Mee Jung, Yu-Jin Jung
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Although many cancer patients are administered radiotherapy for their treatment, the interaction between tumor cells and macrophages in the tumor microenvironment attenuates the curative effects of radiotherapy. The enhanced activation of mTOR signal
Externí odkaz:
https://doaj.org/article/c39a908673e44b8cb5890fa3fad9c857
Autor:
Yura Choi, Shambhunath Bose, Jaegu Seo, Joo-Hyun Shin, Dokyung Lee, Yesol Kim, Seung Goo Kang, Hojun Kim
Publikováno v:
Microorganisms, Vol 9, Iss 10, p 2039 (2021)
Akkermansia muciniphila (A. muciniphila) is a promising probiotic candidate owing to its health-promoting properties. A previous study reported that the pasteurized form of A. muciniphila strains isolated from human stool samples had a beneficial imp
Externí odkaz:
https://doaj.org/article/c4c5931f0f584fa59b66f2dca9c828dd
Autor:
Huijeong Ahn, Gilyoung Lee, Jeongeun Kim, Jeongho Park, Seung Goo Kang, Sung-Il Yoon, Eunsong Lee, Geun-Shik Lee
Publikováno v:
Cells, Vol 10, Iss 7, p 1660 (2021)
Lipocalin-2 (LCN2), a small secretory glycoprotein, is upregulated by toll-like receptor (TLR) signaling in various cells and tissues. LCN2 inhibits bacterial growth by iron sequestration and regulates the innate immune system. Inflammasome activates
Externí odkaz:
https://doaj.org/article/2b425300529248edb93cbf01c3aa698b
Autor:
Huijeong Ahn, Eunsaem Jeon, Jin-Chul Kim, Seung Goo Kang, Sung-il Yoon, Hyun-Jeong Ko, Pyeung-Hyeun Kim, Geun-Shik Lee
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Lentinan extracted from shiitake (Lentinula edodes) is a β-glucan that has been reported as an intravenous anti-tumor polysaccharide via enhancement of the host immune system. In this study, we determined the effect of lentinan on inflammas
Externí odkaz:
https://doaj.org/article/636dd45c6b704796b8c914b24c25d3aa
Autor:
Jeonghyun Lee, Kyong-Oh Shin, Yesol Kim, Jaewon Cho, Hyung W. Lim, Sung-Il Yoon, Geun-Shik Lee, Hyun-Jeong Ko, Pyeung-Hyeun Kim, Yoshikazu Uchida, Kyungho Park, Seung Goo Kang
Publikováno v:
Cells, Vol 9, Iss 6, p 1561 (2020)
The effector function of tumor-infiltrated CD4+ T cells is readily suppressed by many types of immune regulators in the tumor microenvironment, which is one of the major mechanisms of immune tolerance against cancer. Cathelicidin-related antimicrobia
Externí odkaz:
https://doaj.org/article/792589cfda1e409c94fa9496130a61d6
Autor:
Hyun Yong Jin, Hiroyo Oda, Pengda Chen, Chao Yang, Xiaojuan Zhou, Seung Goo Kang, Elizabeth Valentine, Jennifer M Kefauver, Lujian Liao, Yaoyang Zhang, Alicia Gonzalez-Martin, Jovan Shepherd, Gareth J Morgan, Tony S Mondala, Steven R Head, Pyeung-Hyeun Kim, Nengming Xiao, Guo Fu, Wen-Hsien Liu, Jiahuai Han, James R Williamson, Changchun Xiao
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006623 (2017)
MicroRNAs (miRNAs) are thought to exert their functions by modulating the expression of hundreds of target genes and each to a small degree, but it remains unclear how small changes in hundreds of target genes are translated into the specific functio
Externí odkaz:
https://doaj.org/article/da03b2d0e94946c4a74481fd851729b1