Výsledky vyhledávání - "Seung Baek Han"

Akademický článek

Schizophrenia-related microdeletion causes defective ciliary motility and brain ventricle enlargement via microRNA-dependent mechanisms in mice

Autor: Tae-Yeon Eom, Seung Baek Han, Jieun Kim, Jay A. Blundon, Yong-Dong Wang, Jing Yu, Kara Anderson, Damian B. Kaminski, Sadie Miki Sakurada, Shondra M. Pruett-Miller, Linda Horner, Ben Wagner, Camenzind G. Robinson, Matthew Eicholtz, Derek C. Rose, Stanislav S. Zakharenko

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)

Schizophrenia is associated with brain ventricular enlargement. Here, the authors show in mice that 22q11 deletion, which is associated with schizophrenia, causes ventricular enlargement and motility abnormalities in cilia lining ventricle walls via

Externí odkaz: https://doaj.org/article/015f5351a7344fa99035595c0123d9f5

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Akademický článek

Co-targeting myelin inhibitors and CSPGs markedly enhances regeneration of GDNF-stimulated, but not conditioning-lesioned, sensory axons into the spinal cord

Autor: Jinbin Zhai, Hyukmin Kim, Seung Baek Han, Meredith Manire, Rachel Yoo, Shuhuan Pang, George M Smith, Young-Jin Son

Publikováno v: eLife, Vol 10 (2021)

A major barrier to intraspinal regeneration after dorsal root (DR) injury is the DR entry zone (DREZ), the CNS/PNS interface. DR axons stop regenerating at the DREZ, even if regenerative capacity is increased by a nerve conditioning lesion. This pote

Externí odkaz: https://doaj.org/article/801649fb2cb447c1b57b2b765a724588

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Akademický článek

YAP/TAZ initiate and maintain Schwann cell myelination

Autor: Matthew Grove, Hyukmin Kim, Maryline Santerre, Alexander J Krupka, Seung Baek Han, Jinbin Zhai, Jennifer Y Cho, Raehee Park, Michele Harris, Seonhee Kim, Bassel E Sawaya, Shin H Kang, Mary F Barbe, Seo-Hee Cho, Michel A Lemay, Young-Jin Son

Publikováno v: eLife, Vol 6 (2017)

Nuclear exclusion of the transcriptional regulators and potent oncoproteins, YAP/TAZ, is considered necessary for adult tissue homeostasis. Here we show that nuclear YAP/TAZ are essential regulators of peripheral nerve development and myelin maintena

Externí odkaz: https://doaj.org/article/eae26989c1b34d3cb0582278302e9660

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Innate frequency-discrimination hyperacuity in Williams-Beuren syndrome mice

Autor: Christopher M. Davenport, Brett J.W. Teubner, Seung Baek Han, Mary H. Patton, Tae-Yeon Eom, Dusan Garic, Benjamin J. Lansdell, Abbas Shirinifard, Ti-Cheng Chang, Jonathon Klein, Shondra M. Pruett-Miller, Jay A. Blundon, Stanislav S. Zakharenko

Publikováno v: Cell. 185(21)

Williams-Beuren syndrome (WBS) is a rare disorder caused by hemizygous microdeletion of ∼27 contiguous genes. Despite neurodevelopmental and cognitive deficits, individuals with WBS have spared or enhanced musical and auditory abilities, potentiall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a762c6be3ccc53baf17d20fb6d4762
https://pubmed.ncbi.nlm.nih.gov/36152627

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