Zobrazeno 1 - 10
of 137
pro vyhledávání: '"Seung Bae Rho"'
Publikováno v:
Biomolecules & Therapeutics. 31:330-339
Publikováno v:
Cells, Vol 11, Iss 3, p 363 (2022)
High-grade ovarian cancer (HGOC) is the most lethal gynecological cancer, with high metastasis and recurrence. Cancer stem cells (CSCs) are responsible for its apoptosis resistance, cancer metastasis, and recurrence. Thus, targeting CSCs would be a p
Externí odkaz:
https://doaj.org/article/c84018caf4f043ddb9394dcaade97080
Publikováno v:
Biomolecules & Therapeutics. 30:593-602
The human papillomavirus (HPV)-18 E7 (E7) oncoprotein is a major transforming protein that is thought to be involved in the development of cervical cancer. It is well-known that E7 stimulates tumour development by inactivating pRb. However, this alon
Autor:
Hyun Ji Kim, Boram Kim, Hyung Jung Byun, Lu Yu, Tuan Minh Nguyen, Thi Ha Nguyen, Phuong Anh Do, Eun Ji Kim, Kyung Ah Cheong, Kyung Sung Kim, Hiệu Huy Phùng, Mostafizur Rahman, Ji Yun Jang, Seung Bae Rho, Gyeoung Jin Kang, Mi Kyung Park, Ho Lee, Kyeong Lee, Jungsook Cho, Hyo Kyung Han, Sang Geon Kim, Ai Young Lee, Chang Hoon Lee
Publikováno v:
Antioxidants, Vol 10, Iss 12, p 1924 (2021)
ARG2 has been reported to inhibit autophagy in vascular endothelial cells and keratinocytes. However, studies of its mechanism of action, its role in skin fibroblasts, and the possibility of promoting autophagy and inhibiting cellular senescence thro
Externí odkaz:
https://doaj.org/article/8ebf8c9c694b4d3e82405d79dd9abe68
Autor:
Je-Ho Lee, Seung-Hoon Lee, Jinhee Park, Sun-Hee Oh, Dojin Kim, Kyusam Choi, Seung Bae Rho, Kwangbae Kim, Kyoungsook Park
The stability of wild-type p53 is critical for its apoptotic function. In some cancers, wild-type p53 is inactivated by interaction with viral and cellular proteins, and restoration of its activity has therapeutic potential. Here, we identify homeobo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::493bf6ae8a1c76f3571e38d6d87fac22
https://doi.org/10.1158/0008-5472.c.6493068
https://doi.org/10.1158/0008-5472.c.6493068
Autor:
Je-Ho Lee, Seung-Hoon Lee, Jinhee Park, Sun-Hee Oh, Dojin Kim, Kyusam Choi, Seung Bae Rho, Kwangbae Kim, Kyoungsook Park
Supplementary Figures 1-4, with Legends from Homeobox Msx1 Interacts with p53 Tumor Suppressor and Inhibits Tumor Growth by Inducing Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d13d7e2d94bce4ceb202d368c3d2ac6a
https://doi.org/10.1158/0008-5472.22333060
https://doi.org/10.1158/0008-5472.22333060
Autor:
Enkhmend, Enkhtaivan, Hyun Ji, Kim, Boram, Kim, Hyung Jung, Byun, Lu, Yu, Tuan Minh, Nguyen, Thi Ha, Nguyen, Phuong Anh, Do, Eun Ji, Kim, Kyung Sung, Kim, Hiệu Phùng, Huy, Mostafizur, Rahman, Ji Yun, Jang, Seung Bae, Rho, Ho, Lee, Gyeoung Jin, Kang, Mi Kyung, Park, Nan-Hyung, Kim, Chang Ick, Choi, Kyeong, Lee, Hyo Kyung, Han, Jungsook, Cho, Ai Young, Lee, Chang Hoon, Lee
Publikováno v:
Biomolecules & Therapeutics. 30:203-211
Melanogenesis is the production of melanin from tyrosine by a series of enzyme-catalyzed reactions, in which tyrosinase and DOPA oxidase play key roles. The melanin content in the skin determines skin pigmentation. Abnormalities in skin pigmentation
Autor:
Myung Jin Son, Seung Bae Rho, Kwangbae Kim, Mijung Oh, Chaeyeon Son, Sang Yong Song, Kyoungsook Park
Publikováno v:
Cells, Vol 9, Iss 8, p 1854 (2020)
Previously, we demonstrated that the homeoprotein Msx1 interaction with p53 inhibited tumor growth by inducing apoptosis. However, Msx1 can exert its tumor suppressive effect through the inhibition of angiogenesis since growth of the tumor relies on
Externí odkaz:
https://doaj.org/article/eb2be3755ed54ba9aa8819a3aaaeab09
Publikováno v:
Biomolecules & Therapeutics
Metformin is an anti-diabetic drug and has anticancer effects on various cancers. Several studies have suggested that metformin reduces cell proliferation and stimulates cell-cycle arrest and apoptosis. However, the definitive molecular mechanism of
Publikováno v:
Biomolecules & Therapeutics
The imprinted tumour suppressor NOEY2 is downregulated in various cancer types, including ovarian cancers. Recent data suggest that NOEY2 plays an essential role in regulating the cell cycle, angiogenesis and autophagy in tumorigenesis. However, its