Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Seuk-Min Ryu"'
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 231:106333
Publikováno v:
BMB Reports
The evolution of genome editing technology based on CRISPR (clustered regularly interspaced short palindromic repeats) system has led to a paradigm shift in biological research. CRISPR/Cas9-guide RNA complexes enable rapid and efficient genome editin
Autor:
C.-K. Lee, Geung-Joo Lee, Duk Hyoung Kim, Jin-Soo Kim, Sangsu Bae, Sung Jin Chung, Saminathan Subburaj, Seuk-Min Ryu
Publikováno v:
Plant Cell Reports. 35:1535-1544
Site-directed mutagenesis of nitrate reductase genes using direct delivery of purified Cas9 protein preassembled with guide RNA produces mutations efficiently in Petunia × hybrida protoplast system. The clustered, regularly interspaced, short palind
Autor:
Jin-Soo Kim, Seuk Min Ryu, Kyoungmi Kim, Sangtae Kim, Daesik Kim, Gayoung Baek, Kayeong Lim, Eugene Chung, Sung Hyun Kim
Publikováno v:
Nature Biotechnology. 35:435-437
Base editors (BEs) composed of a cytidine deaminase fused to CRISPR-Cas9 convert cytidine to uridine, leading to single-base-pair substitutions in eukaryotic cells. We delivered BE mRNA or ribonucleoproteins targeting the Dmd or Tyr gene via electrop
Autor:
Da Eun Kim, Sangtae Kim, Seuk Min Ryu, Jin-Soo Kim, Hyun Ji Lee, Heon Seok Kim, Eugene Chung, Kyoungmi Kim, Gayoung Baek, Kayeong Lim, Taeyoung Koo
Publikováno v:
Nature biotechnology. 36(6)
Adenine base editors (ABEs) composed of an engineered adenine deaminase and the Streptococcus pyogenes Cas9 nickase enable adenine-to-guanine (A-to-G) single-nucleotide substitutions in a guide RNA (gRNA)-dependent manner. Here we demonstrate applica
Publikováno v:
Nature biotechnology. 35(5)
Cas9-linked deaminases, also called base editors, enable targeted mutation of single nucleotides in eukaryotic genomes. However, their off-target activity is largely unknown. Here we modify digested-genome sequencing (Digenome-seq) to assess the spec
Autor:
Junseok W. Hur, Jin-Soo Kim, Junho K. Hur, Youn Su Lee, Seuk Min Ryu, Kyung Wook Been, Kyoungmi Kim, Gayoung Baek, Sunghyeok Ye
Publikováno v:
Nature Biotechnology. 34:807-808
Autor:
Daesik Kim, Kayeong Lim, Sang-Tae Kim, Sun-heui Yoon, Kyoungmi Kim, Seuk-Min Ryu, Jin-Soo Kim
Publikováno v:
Nature Biotechnology. 35:797-797
Quantitative assessment of gene regulation is critical for mathematical modeling of transcriptional systems for systems biology efforts. Enhancers, also termed cis-regulatory modules (CRMs), are the primary mediators of transcriptional regulation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a0c1945596a030b39074f739b3949bc
https://europepmc.org/articles/PMC3052872/
https://europepmc.org/articles/PMC3052872/